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AMG 9810

AMG 9810 Structure
CAS No.
545395-94-6
Chemical Name:
AMG 9810
Synonyms
9810;CS-2548;AMG 9810;AMG 9810;AMG-9810;AMG 9810 >=98% (HPLC), powder;(2E)-N-(2，3-Dihydro-1，4-benzodi;3-[4-(TERT-BUTYL)PHENYL]-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ACRYLAMIDE;3-(4-tert-Butyl-phenyl)-N-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-acrylamide;(2E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enamide;(2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide
CBNumber:
CB0306302
Molecular Formula:
C21H23NO3
Molecular Weight:
337.41
MOL File:
545395-94-6.mol
MSDS File:
SDS
Modify Date:
2023/6/30 15:45:59
Request For Quotation

AMG 9810 Properties

Boiling point 512.5±50.0 °C(Predicted)
Density 1.175±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO: >5mg/mL
pka 12.22±0.20(Predicted)
form powder
color white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H413
Precautionary statements  P264-P270-P273-P301+P312-P501
Hazard Codes  Xn
Risk Statements  22
WGK Germany  3
NFPA 704
0
2 0

AMG 9810 price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) A2731 AMG 9810 ≥98% (HPLC), powder 545395-94-6 10MG ₹19809.75 2022-06-14 Buy
Sigma-Aldrich(India) A2731 AMG 9810 ≥98% (HPLC), powder 545395-94-6 50MG ₹78665.28 2022-06-14 Buy
Product number Packaging Price Buy
A2731 10MG ₹19809.75 Buy
A2731 50MG ₹78665.28 Buy

AMG 9810 Chemical Properties,Uses,Production

Description

AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat, respectively). Additionally, it has been shown to compete with other modes of TRPV1 activation, including protons (IC50s = 92.7 and 294 nM for human and rat, respectively), heat (IC50s = 15.8 and 21 nM for human and rat, respectively), and the endogenous ligands: anandamide, N-arachidonyl dopamine (IC50s = 8.5 and 260 nM for human and rat, respectively), and oleoyldopamine. In a rat model of inflammatory pain induced by intraplantar injection of complete Freund’s adjuvant, 30-100 mg/kg AMG 9810 reverses thermal and mechanical hyperalgesia.

Uses

AMG 9810 is a competitive antagonist of capsaicin activation of the vanilloid receptor 1 (TRPV1) (IC50s = 24.5 and 85.6 nM for human and rat, respectively). Additionally, it has been shown to compete with other modes of TRPV1 activation, including protons (IC50s = 92.7 and 294 nM for human and rat, respectively), heat (IC50s = 15.8 and 21 nM for human and rat, respectively), and the endogenous ligands: anandamide, N-arachidonyl dopamine (IC50s = 8.5 and 260 nM for human and rat, respectively), and oleoyldopamine. In a rat model of inflammatory pain induced by intraplantar injection of complete Freund’s adjuvant, 30-100 mg/kg AMG 9810 reverses thermal and mechanical hyperalgesia.[Cayman Chemical]

AMG 9810 Preparation Products And Raw materials

Raw materials

Preparation Products

AMG 9810 Suppliers

Global( 82)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 China 11681 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +undefined18621343501 China 33350 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034 China 9357 58 Inquiry
Supplier Advantage
A.J Chemicals 58
ATK CHEMICAL COMPANY LIMITED 60
Chongqing Chemdad Co., Ltd 58
career henan chemical co 58
InvivoChem 58
TargetMol Chemicals Inc. 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Shanghai Acmec Biochemical Technology Co., Ltd. 58
Aladdin Scientific 58
Zhengzhou convergence chemical co., LTD 58

AMG 9810 Spectrum

AMG 9810(545395-94-6)1HNMR

545395-94-6(AMG 9810)Related Search:

PSY-279 IBTU JYL-273 BCTC Acrylamide
(E)-N-(3-METHOXY-PHENYL)-3-PHENYL-ACRYLAMIDE AMG 9810 4-TERT-BUTYLSTYRENE 3-(4-TERT-BUTYL-PHENYL)-PROPENAL
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3-[4-(TERT-BUTYL)PHENYL]-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)ACRYLAMIDE AMG 9810 (2E)-N-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-[4-(1,1-DIMETHYLETHYL)PHENYL]-2-PROPENAMIDE (2E)-N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-dimethylethyl)phenyl]-2-propanamide 2-PropenaMide, N-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-(1,1-diMethylethyl)phenyl]-, (2E)- CS-2548 AMG 9810;AMG-9810 3-(4-tert-Butyl-phenyl)-N-(2,3-dihydro-benzo[1,4]dioxin-6-yl)-acrylamide 9810 AMG 9810 >=98% (HPLC), powder (2E)-3-(4-tert-butylphenyl)-N-(2,3-dihydro-1,4-benzodioxin-6-yl)prop-2-enamide Transient receptor potential channels,inhibit,Inhibitor,AMG-9810,AMG9810,AMG 9810,TRP Channel (2E)-N-(2，3-Dihydro-1，4-benzodi 545395-94-6 Vanilloid/TRPV channel