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2-Morpholinoethyl isocyanide

2-Morpholinoethyl isocyanide Structure
CAS No.
78375-48-1
Chemical Name:
2-Morpholinoethyl isocyanide
Synonyms
MEI;SKL087;2-Morpholinoethyl is;Morpholino ethyl isocyanide;2-MORPHOLINOETHYL ISOCYANIDE;2-Morpholino-ethyl-isocyanate;4-(2-ISOCYANOETHYL)MORPHOLINE;Morpholinyl-4-ethylisocyanid-2;4-(2-Isocyanatoethyl)morpholine;MEI 2-MORPHOLINOETHYL ISOCYANIDE
CBNumber:
CB0321752
Molecular Formula:
C7H12N2O
Molecular Weight:
140.19
MOL File:
78375-48-1.mol
MSDS File:
SDS
Modify Date:
2025/1/27 9:38:02

2-Morpholinoethyl isocyanide Properties

Boiling point 72-73 °C0.7 mm Hg(lit.)
Density 1.017 g/mL at 20 °C(lit.)
refractive index n20/D 1.469
Flash point 110 ºC
storage temp. -20°C
form liquid
BRN 4666990
CAS DataBase Reference 78375-48-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301+H311+H331-H315-H319-H335
Precautionary statements  P261-P280-P301+P310-P302+P352+P312-P304+P340+P311-P305+P351+P338
Hazard Codes  T
Risk Statements  23/24/25-36/37/38
Safety Statements  26-36/37-45
RIDADR  UN 2810 6.1/PG 3
WGK Germany  3
10-21
HazardClass  6.1(b)
PackingGroup  III

2-Morpholinoethyl isocyanide price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 69893 2-Morpholinoethyl isocyanide ≥98.0% (GC) 78375-48-1 50ML ₹6873.88 2022-06-14 Buy
Sigma-Aldrich(India) 69893 2-Morpholinoethyl isocyanide ≥98.0% (GC) 78375-48-1 10ML ₹10110.55 2022-06-14 Buy
Product number Packaging Price Buy
69893 50ML ₹6873.88 Buy
69893 10ML ₹10110.55 Buy

2-Morpholinoethyl isocyanide Chemical Properties,Uses,Production

Uses

2-Morpholinoethyl isocyanide can be used for the synthesis of:

  • Nitrogen acyclic carbene (NAC) complexes to be used as catalysts for the synthesis of phenol and hydration of alkynes.
  • Variety of imidazo[1,2-a]pyridines and α-acylaminoamides by Ugi condensation reaction.
  • 2-Aminobenzoxazoles and 3-aminobenzoxazines having important therapeutic activities.

It can also be used as a ligand in bis-cyclometalated iridium complexes for the organic light emitting diodes (OLEDs).

Synthesis

2-Morpholinoethyl isocyanide is prepared by the reaction of 2-morpholinoethylamine with Formic Acid in boiling toluene with a water separator, to yield the formamide which is treated either with Phosgene and Triethylamine in CH2Cl2 or with Phosphorus Oxychloride and Diisopropylamine. The use of diisopropylamine as base is favored as yields are improved, typically to 68%. Trichloroacetic Anhydride has also been used as an alternative for COCl2, giving a yield of 74%.

2-Morpholinoethyl isocyanide Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 71)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CONIER CHEM AND PHARMA LIMITED +8618523575427 China 49732 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. +86-0571-88938639 +8617705817739 China 52849 58 Inquiry
Henan Alfa Chemical Co., Ltd +8615838112936 China 13194 58 Inquiry
PT CHEM GROUP LIMITED +86-85511178; +86-85511178; China 35425 58 Inquiry
LEAPCHEM CO., LTD. +86-852-30606658 China 43340 58 Inquiry
Aladdin Scientific United States 57505 58 Inquiry
Amadis Chemical Company Limited 571-89925085 China 131957 58 Inquiry
Shanghai Chaoyan Biotechnology Co., Ltd. 021-50840550 CHINA 6210 58 Inquiry
Shanghai Jingke Chemical Technology Co., Ltd. 021-54997581 13524423207 CHINA 6972 58 Inquiry
Shanghai Yuda Industrial Co., Ltd. 021-64133189 13788995069 CHINA 6105 58 Inquiry
Morpholino ethyl isocyanide Morpholine, 4-(2-isocyanoethyl)- MEI 2-MORPHOLINOETHYL ISOCYANIDE Morpholinyl-4-ethylisocyanid-2 4-(2-Isocyanatoethyl)morpholine 2-Morpholinoethyl is 2-Morpholinoethyl isocyanide >=98.0% (GC) 2-MORPHOLINOETHYL ISOCYANIDE 1-N-(2-ISOCYANOETHYL)-MORPHOLINE 4-(2-ISOCYANOETHYL)MORPHOLINE 2-Morpholino-ethyl-isocyanate SKL087 MEI 78375-48-1 Building Blocks Heterocyclic Building Blocks Morpholines Nitro / Nitriles