N-ACETYLTRYPTAMINE
- CAS No.
- 1016-47-3
- Chemical Name:
- N-ACETYLTRYPTAMINE
- Synonyms
- Acetotryptamide;N-ACETYLTRYPTAMINE;Nb-Acetyltryptamine;N-(2-(1H-Indol-3-yl);N10-Acetyltryptamine;TRYPTAMINE, N-ACETYL-;N-Acetyltryptamine >N-Acetyltryptamine;3-(2-Acetamidoethyl)indole;3-(2-N-ACETYLAMINOETHYL)INDOLE
- CBNumber:
- CB0329617
- Molecular Formula:
- C12H14N2O
- Molecular Weight:
- 202.25
- MOL File:
- 1016-47-3.mol
- Modify Date:
- 2023/9/20 16:43:00
| Melting point | 74.0 to 78.0 °C |
|---|---|
| Boiling point | 200°C/0.2mmHg(lit.) |
| Density | 1.164±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | alcohol: soluble |
| form | powder |
| pka | 16.48±0.46(Predicted) |
| color | White to Light yellow to Light orange |
| λmax | 290nm(MeOH)(lit.) |
| CAS DataBase Reference | 1016-47-3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|---|---|
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P501-P264-P280-P303+P361+P353-P301+P330+P331-P363-P304+P340+P310-P305+P351+P338+P310-P405 |
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| HS Code | 2933.99.8290 |
N-ACETYLTRYPTAMINE price More Price(2)
N-ACETYLTRYPTAMINE Chemical Properties,Uses,Production
Description
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.
Uses
N-acetyl Tryptamine is a structural analog of melatonin (5-methoxy-N-acetyltryptamine; ) that binds the melatonin MT2 receptor (Ki = 41 nM). It acts as a melatonin receptor antagonist in frog skin and chicken retina and as a partial agonist in rabbit retina. N-acetyl Tryptamine is also a reaction product of assays for serotonin N-acetyltransferase, the penultimate enzyme in the melatonin biosynthetic pathway.
Definition
ChEBI: A tryptamine compound having an acetyl substituent attached to the side-chain amino function.
Enzyme inhibitor
This partial receptor agonist (FW = 202.26 g/mol; CAS 1016-47-3; Soluble to 100 mM in DMSO) is a melatonin (or 5-methoxy-N-acetyltryptamine) mimic and is more potent than melatonin in inhibiting dopamine release fom presynaptic melatonin receptor site of rabbit retina labeled in vitro with [3H]dopamine.
References
Moro, Graziano, Coussio, Phytochern., 14,827 (1975)
N-ACETYLTRYPTAMINE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Alfa Chemistry | United States | 2344 | 58 | Inquiry | |
| Aston Chemical | 13000000000 | United States | 1634 | 58 | Inquiry |
| Alfa Chemistry | United States | 24072 | 58 | Inquiry | |
| Shanghai Qyubiotech Co., Ltd. | +86-086-021-37596619 +8618019359838 | China | 300 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
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