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Tryptamine

Tryptamine Structure
CAS No.
61-54-1
Chemical Name:
Tryptamine
Synonyms
L-TRYPTAMINE;1H-INDOLE-3-ETHANAMINE;TRYPTAMINE CAS 61-54-1;2-(1H-INDOL-3-YL)ETHANAMINE;2-(1H-indol-3-yl)ethan-1-aMine hydrochloride;TRIPTAMINE;3-(2-AMINOETHYL)INDOLE;b mk-2;Tryptamin;ryptamine
CBNumber:
CB8192006
Molecular Formula:
C10H12N2
Molecular Weight:
160.22
MOL File:
61-54-1.mol
MSDS File:
SDS
Modify Date:
2024/8/2 20:38:39

Tryptamine Properties

Melting point 113-116 °C (lit.)
Boiling point 137 °C/0.15 mmHg (lit.)
Density 0.9787 (rough estimate)
refractive index 1.6210 (estimate)
Flash point 185 °C
storage temp. 2-8°C
solubility water: soluble1g/L at 20°C
pka 10.2(at 25℃)
form crystalline
color white
PH 11.07 (10g/l, H2O, 24.7℃)
Water Solubility negligible
Sensitive Air Sensitive
Merck 14,9796
BRN 125513
CAS DataBase Reference 61-54-1(CAS DataBase Reference)
NIST Chemistry Reference 1H-Indole-3-ethanamine(61-54-1)
EPA Substance Registry System Tryptamine (61-54-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H317-H318
Precautionary statements  P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  20/21/22-36/37/38-41-37/38-22
Safety Statements  24/25-36/37/39-36-26
WGK Germany  3
RTECS  NL4020000
8-23
HazardClass  IRRITANT
HS Code  28259080
HS Code  29339990
NFPA 704
1
2 0

Tryptamine price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 193747 Tryptamine ≥97% 61-54-1 10G ₹2392.33 2022-06-14 Buy
Sigma-Aldrich(India) 76706 Tryptamine analytical standard 61-54-1 100MG ₹5780.55 2022-06-14 Buy
Sigma-Aldrich(India) 193747 Tryptamine ≥97% 61-54-1 50G ₹8724.95 2022-06-14 Buy
TCI Chemicals (India) T0890 Tryptamine 61-54-1 25G ₹5400 2022-05-26 Buy
ottokemi T 2456 Tryptamine, 99% 61-54-1 250mg ₹1404 2022-05-26 Buy
Product number Packaging Price Buy
193747 10G ₹2392.33 Buy
76706 100MG ₹5780.55 Buy
193747 50G ₹8724.95 Buy
T0890 25G ₹5400 Buy
T 2456 250mg ₹1404 Buy

Tryptamine Chemical Properties,Uses,Production

Description

Tryptamine is an indole alkaloid and intermediate in the biosynthesis of serotonin and the phytohormone melatonin in plants. It increases the levels of the terpenoid indole alkaloids ajmalicine, strictosidine, and catharanthine in cultures of C. roseus. Tryptamine is also a product of tryptophan metabolism in mammals. Tryptamine derivatives have been synthetically produced as hallucinogenic drugs of abuse that act on the serotonergic system.

Chemical Properties

Tryptamine is a biogenic imine derived from the decarboxylation of tryptophan. It is a white to orange crystalline Powder, melting point 118°C (decomposition at 145-146°C). Soluble in ethanol and acetone, almost insoluble in ether, benzene, chloroform and water.

Uses

Tryptamine is a monoamine alkaloid found in plants. Tryptamine is commonly used in the preparation of biologically active compounds such as neurotransmitters and psychedelics.

Definition

ChEBI: Tryptamine is an aminoalkylindole consisting of indole having a 2-aminoethyl group at the 3-position. It has a role as a human metabolite, a plant metabolite and a mouse metabolite. It is an aminoalkylindole, an indole alkaloid, an aralkylamino compound and a member of tryptamines. It is a conjugate base of a tryptaminium.

Preparation

Tryptamine, a monoamine alkaloid containing an indole ring structure is derived by the decarboxylation of amino acid tryptophan.
synthesis of tryptamine
The synthesis of tryptamines is typically conducted following a classic route starting with a Mannich reaction of an indole heterocycle, followed by quaternization of the amine, nucleophilic substitution with highly toxic cyanide and final reduction.

General Description

Tryptamines which are usually found in plants, fungi, animals, etc. are categorized under the monoamine alkaloids class of compounds.

Purification Methods

Crystallise tryptamine from *benzene, Et2O (m 114o) or pet ether (m 118o). It has UV: 222n 276, 282 and 291nm (EtOH) and max 226, 275, 281 and 290nm (HCl). [Beilstein 22 II 346, 22 III/IV 4319, 22/10 V 45.]

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