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L-5-Hydroxytryptophan

L-5-Hydroxytryptophan Structure
CAS No.
4350-09-8
Chemical Name:
L-5-Hydroxytryptophan
Synonyms
5-HTP;OXITRIPTAN;(S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid;L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID;L-5-HTP;Griffonia seed;5-hydroxy-l-tryptopha;5-Hydroxy-L-tryptophane;L-HTP;quietim
CBNumber:
CB9110025
Molecular Formula:
C11H12N2O3
Molecular Weight:
220.22
MOL File:
4350-09-8.mol
MSDS File:
SDS
Modify Date:
2024/11/13 18:13:23

L-5-Hydroxytryptophan Properties

Melting point 270 °C (dec.) (lit.)
alpha -32.5 º (c=1,H2O on dry basis)
Boiling point 361.16°C (rough estimate)
Density 0.902 g/mL at 25 °C (lit.)
refractive index n20/D 1.4850(lit.)
Flash point 175 °F
storage temp. 2-8°C
solubility H2O: 10 mg/mL
form solid
pka 2.22±0.10(Predicted)
color white
optical activity [α]22/D 30°, c = 1 in H2O
Water Solubility Slightly soluble
Merck 14,4847
BRN 88200
LogP -0.140 (est)
CAS DataBase Reference 4350-09-8(CAS DataBase Reference)
EPA Substance Registry System L-5-Hydroxytryptophan (4350-09-8)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H301
Precautionary statements  P301+P330+P331+P310
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38-65-20/21/22-20/21
Safety Statements  36-26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  YN7110000
3-10
TSCA  Yes
HazardClass  6.1
PackingGroup  III
HS Code  29339990
NFPA 704
1
2 0

L-5-Hydroxytryptophan price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) H9772 5-Hydroxy-L-tryptophan powder 4350-09-8 100MG ₹3464 2022-06-14 Buy
Sigma-Aldrich(India) H9772 5-Hydroxy-L-tryptophan powder 4350-09-8 250MG ₹4113.5 2022-06-14 Buy
Sigma-Aldrich(India) H9772 5-Hydroxy-L-tryptophan powder 4350-09-8 1G ₹7923.9 2022-06-14 Buy
Sigma-Aldrich(India) PHR2597 5-Hydroxy-L-tryptophan Pharmaceutical Secondary Standard; Certified Reference Material 4350-09-8 100MG ₹22764.98 2022-06-14 Buy
Sigma-Aldrich(India) H9772 5-Hydroxy-L-tryptophan powder 4350-09-8 5G ₹28025.93 2022-06-14 Buy
Product number Packaging Price Buy
H9772 100MG ₹3464 Buy
H9772 250MG ₹4113.5 Buy
H9772 1G ₹7923.9 Buy
PHR2597 100MG ₹22764.98 Buy
H9772 5G ₹28025.93 Buy

L-5-Hydroxytryptophan Chemical Properties,Uses,Production

Chemical Properties

white to pale grey powder

Uses

A labelled metabolite of Tryptophan

General Description

Colorless to pale pink crystals.

Air & Water Reactions

L-5-Hydroxytryptophan is sensitive to air. Slightly water soluble .

Reactivity Profile

L-5-Hydroxytryptophan reacts with bases. .

Fire Hazard

Flash point data for L-5-Hydroxytryptophan are not available, however, L-5-Hydroxytryptophan is probably combustible.

Trade name

Levothym (Promonta Lundbeck, Germany), Lévotonine (Panpharma, France), Oxyfan (Coli, Italy), Tript-OH (Sigma- Tai, Italy).

Purification Methods

Likely impurities are 5-hydroxy-D-tryptophan and 5-benzyloxytryptophan. Crystallise 5-hydroxy-L-tryptophan under nitrogen from water by adding EtOH. Store it under nitrogen. Also dissolve it in the minimum volume of hot H2O (~0.7g in 4mL) under nitrogen (charcoal) and allowed it to crystallise at 5o. The picrolonate crystallises from H2O with m 184-186o(dec). [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2732-2737 1961, Morris & Armstrong J Org Chem 22 306 1957, Beilstein 22/14 V 278.]

L-5-Hydroxytryptophan Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 475)Suppliers
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Ambe Phytoextracts Private Limited +91-1143764376 +91-1143764376 New Delhi, India 37 58 Inquiry
Chemical Resources +91-1725022460 +91-1725022460 Haryana, India 17 58 Inquiry
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Otto Chemie Pvt. Ltd. +91 9820041841 Mumbai, India 5870 58 Inquiry
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Triveni chemicals 08048762458 New Delhi, India 6088 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Central Drug House(P) Ltd. 91-11-49404040 New Delhi, India 6157 58 Inquiry
L-5-HYDROXYTRYPTOPHAN HYDRATE L-5-HYDROXYTRYPTOPHAN 2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPIONIC ACID (-)-5-HYDROXY-L-TRYPTOPHAN 5-HYDROXY-L-TRP-OH pretonine L-5-Hydroxytryptophan, 99% 5GR L-5-HTP, L-2-Amino-3-(5-hydroxyindolyl)propionic acid 5-Hydroxy-L-tryphophane 5-Hydroxy-L-tryptophan 98% (calc. on dried substance) 5-Hydroxy-L-tryptophan(5-HTP) 5-Hydroxy-L-tryptophan99% L-Trp(5-OH)-OH 5-Hydroxy-L-tryptophan, Free Acid L-Tryptophan, 5-hydroxy- l-2-amino-3-[3-(5-hydroxyindole)]propionic acid 5-HYDROXY-1-TRYTOPHAN 5-Hydroxyl-L-tryptophan. quietim 5-HYDROXY-L-TRYPTOPHAN 99,0 % min H-L-Trp(5-OH)-OH 5-HTP Griffonia Seed L-2-Amino-3-(5-hydroxyindolyl)propionic acid, L-5-HTP 5-HYDROXY-L-TRYPTOPHAN 99% 5-HTP HPLC L-2-Amino-3-(5-hydroxyindolyl)propionic acid L-5-HTP 5-HTP 5-Hydroxy-L-tryptophan, Dihydrate 5-HYDROXY-TRP-OH C5-HYDROXY-L-TRYPTOPHAN H-5-HYDROXY-TRP-OH H-TRP(5-OH)-OH (S)-2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)-PROPIONIC ACID (2S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid Levothym L-5-Hydroxytryptophan,99% L-5-Hydroxytryptopha (S)-5-Hydroxytryptophan 5-Hydroxytryptophan(5-HTP,Oxitriptan) (S)-2-AMino-3-(5-hydroxy-1H-indol-3-yl)-propionic acid, C5-Hydroxy-L-tryptophan, 5-HTP, Oxitriptan 5-Hydroxy-L-tryptophan-d 3 L-5-Hydroxytryptophan, 99% 1GR L-oxitriptan L-5-Hydroxytryptophan USP/EP/BP N-Acetyltryptophan EP Impurity D laevo-oxitriptan 5-Hydroxy L-trpytophan, 99% TIANFU-CHEM CAS NO.4350-09-8 Polyurethane foams 5-Hydroxy-L-Tryptophan extrapure, 99% 5-Hydroxy-L-tryptophan (1329913) L-HTP Tryptophan Impurity 9(Tryptophan EP Impurity D) L-5-Hydroxytryptophan (Synonyms: L-5-HTP Ghana seed extract L-5-Hydroxytryptophan (L-5-HTP L-5-Hydroxytryptophan(Tryptophan EP Impurity D) HPLC>=98% 5-Hydroxy-L-tryptophan> (S)-2-Amino-3-(5-hydroxy-1H-indol-3 L-5-HTP