L-5-Hydroxytryptophan
- CAS No.
- 4350-09-8
- Chemical Name:
- L-5-Hydroxytryptophan
- Synonyms
- 5-HTP;OXITRIPTAN;(S)-2-Amino-3-(5-hydroxy-1H-indol-3-yl)propanoic acid;L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID;L-5-HTP;Griffonia seed;5-hydroxy-l-tryptopha;5-Hydroxy-L-tryptophane;L-HTP;quietim
- CBNumber:
- CB9110025
- Molecular Formula:
- C11H12N2O3
- Molecular Weight:
- 220.22
- MOL File:
- 4350-09-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/11/13 18:13:23
Melting point | 270 °C (dec.) (lit.) |
---|---|
alpha | -32.5 º (c=1,H2O on dry basis) |
Boiling point | 361.16°C (rough estimate) |
Density | 0.902 g/mL at 25 °C (lit.) |
refractive index |
n |
Flash point | 175 °F |
storage temp. | 2-8°C |
solubility | H2O: 10 mg/mL |
form | solid |
pka | 2.22±0.10(Predicted) |
color | white |
optical activity | [α]22/D 30°, c = 1 in H2O |
Water Solubility | Slightly soluble |
Merck | 14,4847 |
BRN | 88200 |
LogP | -0.140 (est) |
CAS DataBase Reference | 4350-09-8(CAS DataBase Reference) |
EPA Substance Registry System | L-5-Hydroxytryptophan (4350-09-8) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS06 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H301 | |||||||||
Precautionary statements | P301+P330+P331+P310 | |||||||||
Hazard Codes | Xn,Xi | |||||||||
Risk Statements | 22-36/37/38-65-20/21/22-20/21 | |||||||||
Safety Statements | 36-26 | |||||||||
RIDADR | UN 2811 6.1/PG 3 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | YN7110000 | |||||||||
F | 3-10 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1 | |||||||||
PackingGroup | III | |||||||||
HS Code | 29339990 | |||||||||
NFPA 704 |
|
L-5-Hydroxytryptophan price More Price(14)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | H9772 | 5-Hydroxy-L-tryptophan powder | 4350-09-8 | 100MG | ₹3464 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H9772 | 5-Hydroxy-L-tryptophan powder | 4350-09-8 | 250MG | ₹4113.5 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H9772 | 5-Hydroxy-L-tryptophan powder | 4350-09-8 | 1G | ₹7923.9 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR2597 | 5-Hydroxy-L-tryptophan Pharmaceutical Secondary Standard; Certified Reference Material | 4350-09-8 | 100MG | ₹22764.98 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | H9772 | 5-Hydroxy-L-tryptophan powder | 4350-09-8 | 5G | ₹28025.93 | 2022-06-14 | Buy |
L-5-Hydroxytryptophan Chemical Properties,Uses,Production
Chemical Properties
white to pale grey powder
Uses
A labelled metabolite of Tryptophan
General Description
Colorless to pale pink crystals.
Air & Water Reactions
L-5-Hydroxytryptophan is sensitive to air. Slightly water soluble .
Reactivity Profile
L-5-Hydroxytryptophan reacts with bases. .
Fire Hazard
Flash point data for L-5-Hydroxytryptophan are not available, however, L-5-Hydroxytryptophan is probably combustible.
Trade name
Levothym (Promonta Lundbeck, Germany), Lévotonine (Panpharma, France), Oxyfan (Coli, Italy), Tript-OH (Sigma- Tai, Italy).
Purification Methods
Likely impurities are 5-hydroxy-D-tryptophan and 5-benzyloxytryptophan. Crystallise 5-hydroxy-L-tryptophan under nitrogen from water by adding EtOH. Store it under nitrogen. Also dissolve it in the minimum volume of hot H2O (~0.7g in 4mL) under nitrogen (charcoal) and allowed it to crystallise at 5o. The picrolonate crystallises from H2O with m 184-186o(dec). [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2732-2737 1961, Morris & Armstrong J Org Chem 22 306 1957, Beilstein 22/14 V 278.]
L-5-Hydroxytryptophan Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Ambe Phytoextracts Private Limited | +91-1143764376 +91-1143764376 | New Delhi, India | 37 | 58 | Inquiry |
Chemical Resources | +91-1725022460 +91-1725022460 | Haryana, India | 17 | 58 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5870 | 58 | Inquiry |
Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4315 | 58 | Inquiry |
Triveni chemicals | 08048762458 | New Delhi, India | 6088 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6157 | 58 | Inquiry |
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