Tryptophol
- CAS No.
- 526-55-6
- Chemical Name:
- Tryptophol
- Synonyms
- 2-(1H-INDOL-3-YL)ETHAN-1-OL;3-(2-HYDROXYETHYL)INDOLE;INDOLE-3-ETHANOL;IEA;Indoleethanol;3-INDOLEETHANOL;B-3-INDOLYLETHANOL;BETA-3-INDOLYLETHANOL;DK803;NSC 3884
- CBNumber:
- CB0782869
- Molecular Formula:
- C10H11NO
- Molecular Weight:
- 161.2
- MOL File:
- 526-55-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/12/18 13:37:16
Melting point | 56-59 °C(lit.) |
---|---|
Boiling point | 174 °C (2.02527 mmHg) |
Density | 1.0840 (rough estimate) |
refractive index | 1.5200 (estimate) |
Flash point | 255 °C |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | methanol: 0.1 g/mL, clear |
pka | 15.16±0.10(Predicted) |
form | Crystalline Mass, Crystals, Flakes or Powder |
color | Off-white to brown |
Water Solubility | 10 g/L (20 ºC) |
Merck | 14,9798 |
BRN | 125553 |
InChIKey | MBBOMCVGYCRMEA-UHFFFAOYSA-N |
LogP | 1.280 (est) |
CAS DataBase Reference | 526-55-6(CAS DataBase Reference) |
NIST Chemistry Reference | 1H-indole-3-ethanol(526-55-6) |
EPA Substance Registry System | 1H-Indole-3-ethanol (526-55-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P271-P280 | |||||||||
Hazard Codes | Xi | |||||||||
Safety Statements | 24/25 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | KL3685000 | |||||||||
F | 8 | |||||||||
Hazard Note | Irritant | |||||||||
TSCA | Yes | |||||||||
HS Code | 29339990 | |||||||||
Toxicity | LD50 intraperitoneal in mouse: 351mg/kg | |||||||||
NFPA 704 |
|
Tryptophol price More Price(4)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | T90301 | 3-(2-Hydroxyethyl)indole 97% | 526-55-6 | 5G | ₹5434.15 | 2022-06-14 | Buy |
TCI Chemicals (India) | I0030 | 3-Indoleethanol min. 98.0 % | 526-55-6 | 1G | ₹2000 | 2022-05-26 | Buy |
TCI Chemicals (India) | I0030 | 3-Indoleethanol min. 98.0 % | 526-55-6 | 5G | ₹4500 | 2022-05-26 | Buy |
TCI Chemicals (India) | I0030 | 3-Indoleethanol min. 98.0 % | 526-55-6 | 25G | ₹18300 | 2022-05-26 | Buy |
Tryptophol Chemical Properties,Uses,Production
Chemical Properties
3-(2-Hydroxyethyl)indole [526-55-6], tryptophol, C10H11NO, Mr 161.20, mp 59 ℃, bp 174 ℃, (2 kPa) forms colorless prisms or flakes that are readily soluble in methanol, ethanol, diethyl ether, chloroform, and acetone, soluble in benzene, and slightly soluble in water. It is produced by reacting methyl-1H-indole-3-acetate with lithium aluminum hydride, or through reduction of methyl-1H-indole-3-glyoxylate with sodium borohydride. The antihypertensive Indoramin is produced from tryptophol.
Uses
Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.
Definition
ChEBI: An indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2.
Purification Methods
Crystallise it from diethyl ether/pet ether, *C6H6, *C6H6/pet ether. The picrate has m 100-101o (from *C6H6). [Beilstein 21 I 218, 21 II 49, 21 III/IV 788, 21/3 V 61.]
Tryptophol Preparation Products And Raw materials
Raw materials
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Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6700 | 30 | Inquiry |
CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6257 | 58 | Inquiry |
A.J Chemicals | 91-9810153283 | New Delhi, India | 6100 | 58 | Inquiry |
TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6768 | 58 | Inquiry |
SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6514 | 58 | Inquiry |
Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6739 | 58 | Inquiry |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | China | 8806 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +8617531153977 | China | 5856 | 58 | Inquiry |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | China | 5889 | 58 | Inquiry |
Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | China | 29793 | 60 | Inquiry |
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