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Tryptophol

Tryptophol Structure
CAS No.
526-55-6
Chemical Name:
Tryptophol
Synonyms
2-(1H-INDOL-3-YL)ETHAN-1-OL;3-(2-HYDROXYETHYL)INDOLE;INDOLE-3-ETHANOL;IEA;Indoleethanol;3-INDOLEETHANOL;B-3-INDOLYLETHANOL;BETA-3-INDOLYLETHANOL;DK803;NSC 3884
CBNumber:
CB0782869
Molecular Formula:
C10H11NO
Molecular Weight:
161.2
MOL File:
526-55-6.mol
MSDS File:
SDS
Modify Date:
2024/6/3 15:34:43

Tryptophol Properties

Melting point 56-59 °C(lit.)
Boiling point 174 °C (2.02527 mmHg)
Density 1.0840 (rough estimate)
refractive index 1.5200 (estimate)
Flash point 255 °C
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility methanol: 0.1 g/mL, clear
pka 15.16±0.10(Predicted)
form Crystalline Mass, Crystals, Flakes or Powder
color Off-white to brown
Water Solubility 10 g/L (20 ºC)
Merck 14,9798
BRN 125553
InChIKey MBBOMCVGYCRMEA-UHFFFAOYSA-N
LogP 1.280 (est)
CAS DataBase Reference 526-55-6(CAS DataBase Reference)
NIST Chemistry Reference 1H-indole-3-ethanol(526-55-6)
EPA Substance Registry System 1H-Indole-3-ethanol (526-55-6)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Hazard Codes  Xi
Safety Statements  24/25
WGK Germany  3
RTECS  KL3685000
8
Hazard Note  Irritant
TSCA  Yes
HS Code  29339990
Toxicity LD50 intraperitoneal in mouse: 351mg/kg
NFPA 704
1
1 0

Tryptophol price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T90301 3-(2-Hydroxyethyl)indole 97% 526-55-6 5G ₹5434.15 2022-06-14 Buy
TCI Chemicals (India) I0030 3-Indoleethanol min. 98.0 % 526-55-6 1G ₹2000 2022-05-26 Buy
TCI Chemicals (India) I0030 3-Indoleethanol min. 98.0 % 526-55-6 5G ₹4500 2022-05-26 Buy
TCI Chemicals (India) I0030 3-Indoleethanol min. 98.0 % 526-55-6 25G ₹18300 2022-05-26 Buy
Product number Packaging Price Buy
T90301 5G ₹5434.15 Buy
I0030 1G ₹2000 Buy
I0030 5G ₹4500 Buy
I0030 25G ₹18300 Buy

Tryptophol Chemical Properties,Uses,Production

Chemical Properties

3-(2-Hydroxyethyl)indole [526-55-6], tryptophol, C10H11NO, Mr 161.20, mp 59 ℃, bp 174 ℃, (2 kPa) forms colorless prisms or flakes that are readily soluble in methanol, ethanol, diethyl ether, chloroform, and acetone, soluble in benzene, and slightly soluble in water. It is produced by reacting methyl-1H-indole-3-acetate with lithium aluminum hydride, or through reduction of methyl-1H-indole-3-glyoxylate with sodium borohydride. The antihypertensive Indoramin is produced from tryptophol.

Uses

Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.

Definition

ChEBI: An indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2.

Purification Methods

Crystallise it from diethyl ether/pet ether, *C6H6, *C6H6/pet ether. The picrate has m 100-101o (from *C6H6). [Beilstein 21 I 218, 21 II 49, 21 III/IV 788, 21/3 V 61.]

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B-3-INDOLEETHANOL 3-(BETA-HYDROXYETHYL)INDOLE 2-(1H-INDOL-3-YL)-ETHANOL 2-(3-INDOLE)ETHANOL RARECHEM AH BS 0132 TIMTEC-BB SBB003950 TRYPTOTHOL TRYPTOPHOL 'TRYPTOPHOL' 1H-Indole-3-ethanol 2-(3-Indolylethanol 3-indolyl-ethano 3-Indolylethanol 3-(2-Hydroxyethyl)indole 97% Color alcohol NSC 3884 3-(2-Hydroxyethyl)indole Vetec(TM) reagent grade, 97% 3-Indoleethanol 3-(2-Hydroxyethyl)indole beta-3-Indolylethanol 2-(1H-Indol-3-yl)ethan-1-ol beta-(3-Indole)ethanol dl-Tryptophanol Ethanol, 2-indol-3-yl- Ethanol, 3-indolyl- 3-β-hydroxyethyl in-dole β-indolylethylalcohol 3-(2-Hydroxyethyl)indole~2-(3-Indolyl)ethanol beta-indol-3-ylethanol Tryptophol (Indole-3-ethanol) TRYPTOPHOL ULTRA-PURE 99.5% Tryptophol,97% 3-(2-HYDROXYETHYL)INDOLE (TRYPTOPHOL) Tryptophol, 3-Indoleethanol TRYPTOPHOL(IEt) 3-(2-Hydroxyethyl)-1H-indole Tryptophol, 2-(1H-Indol-3-yl)ethan-1-ol Tryptophol, 97% 5GR Indole-3-ethanol (Tryptophol),beta-3-Indolylethanol 3-Indoleethanol> ryptophol Tryptopho ?-indol-3-ylethanol INDOLE-3-ETHANOL B-3-INDOLYLETHANOL BETA-3-INDOLYLETHANOL 3-INDOLEETHANOL 2-(1H-INDOL-3-YL)ETHAN-1-OL 3-(2-HYDROXYETHYL)INDOLE IEA Indoleethanol Tryptophol (6CI) DK803 3-Indoleethanol , Tryptophol 526-55-6 Indoles Simple Indoles Heterocyclic Building Blocks Building Blocks Heterocyclic Compounds Indoles