BMS-986205
![BMS-986205 Structure](CAS/20180808/GIF/1923833-60-6.gif)
- CAS No.
- 1923833-60-6
- Chemical Name:
- BMS-986205
- Synonyms
- Linrodostat;CS-2743;F001287;F-001287;BMS-986205;BMS 986205;BMS986205;Linrodostat(BMS-986205);BMS-986205(Linrodostat);LINRODOSTAT;BMS 986205;BMS986205;(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
- CBNumber:
- CB03339862
- Molecular Formula:
- C24H24ClFN2O
- Molecular Weight:
- 410.91
- MOL File:
- 1923833-60-6.mol
- Modify Date:
- 2024/7/2 8:54:58
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
---|---|
Signal word | Warning |
Hazard statements | H302-H315-H319-H335 |
Precautionary statements | P261-P305+P351+P338 |
BMS-986205 Chemical Properties,Uses,Production
Description
BMS-986205, also known as Linrodostat, ONO-7701 and F001287, a potent and selective, orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities.
Biological Activity
Linrodostat (BMS-986205, ONO-7701) is an irreversible inhibitor of IDO1 with an IC50 of 1.7 nM. It inhibits kynurenine production with IC50 values of 1.7, 1.1 and > 2000 in human HeLa, HEK293 expressing human IDO-1 and tryptophan-2, 3-dioxygenase cell-based assays.
BMS-986205 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 100)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30250 | 58 | Inquiry |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | China | 10522 | 58 | Inquiry |
Hangzhou Proserre Chemical Co.,Ltd. | +86-571-86088112 | China | 1077 | 58 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
LEAP CHEM CO., LTD. | +86-852-30606658 | China | 24738 | 58 | Inquiry |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | China | 49739 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | China | 3581 | 58 | Inquiry |
1923833-60-6(BMS-986205)Related Search:
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Q-VD-OPh hydrate
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BMS-986205
LINRODOSTAT;BMS 986205;BMS986205
BMS 986205;BMS986205
BMS-986205(Linrodostat)
CS-2743
(2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamid
Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methyl-, cis-(αR)-
Linrodostat
(R)-N-(4-Chlorophenyl)-2-(cis-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide
Linrodostat(BMS-986205)
cis-(αR)-N-(4-Chlorophenyl)-4-(6-fluoro-4-quinolinyl)-α-methylcyclohexaneacetamide
cis-(alphaR)-N-(4-Chlorophenyl)-4-(6-fluoro-quinolin-4-yl)-alpha-methylcyclohexaneacetamide
F001287
F-001287
1923833-60-6
923833-60-6
C24H24ClFN2O
API