PD-L1 inhibitor 1

PD-L1 inhibitor 1 Structure
CAS No.
1675203-84-5
Chemical Name:
PD-L1 inhibitor 1
Synonyms
BMS-202;CS-2416;PD1 inhibitor 2;PD 1 inhibitor 2;PD-1 inhibitor 2;PD-L1 inhibitor 2;PD-L1 inhibitor 1;PD1-PDL1 inhibitor 2;PD-1/PD-L1 inhibitor 2(BMS-202);BMS202 (PD-1/PD-L1 inhibitor 2)
CBNumber:
CB13043328
Molecular Formula:
C25H29N3O3
Molecular Weight:
419.52
MOL File:
1675203-84-5.mol
Modify Date:
2023/6/8 9:02:36

PD-L1 inhibitor 1 Properties

Boiling point 611.4±55.0 °C(Predicted)
Density 1.133±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility Soluble in DMSO (up to at least 25 mg/ml) or in Ethanol (up to at least 25 mg/ml)
pka 16.06±0.46(Predicted)
form solid
color White
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
NFPA 704
0
2 0

PD-L1 inhibitor 1 Chemical Properties,Uses,Production

Description

The programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) interaction plays a dominant role in the suppression of T cell responses, especially in a tumor microenvironment, protecting tumor cells from lysis. PD-1/PD-L1 inhibitor 2 is reported to prevent the interaction of PD-L1 with PD-1 with an IC50 value of 18 nM.

PD-L1 inhibitor 1 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 94)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Fuxin Pharmaceutical +86-021-021-50872116 +8613122107989 China 10297 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6393 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
RR Scientific LLC +86-13917743231 United States 878 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry

PD-L1 inhibitor 1 Spectrum

PD-L1 inhibitor 1 PD1-PDL1 inhibitor 2 N-[2-[[[2-Methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]-3-pyridinyl]methyl]amino]ethyl]acetamide BMS-202 Acetamide, N-[2-[[[2-methoxy-6-[(2-methyl[1,1'-biphenyl]-3-yl)methoxy]-3-pyridinyl]methyl]amino]ethyl]- PD 1 inhibitor 2 PD1 inhibitor 2 PD-1 inhibitor 2 PD-L1 inhibitor 2 PD-L1 INHIBITOR 2;PD-1 INHIBITOR 2;PD1 INHIBITOR 2;PD 1 INHIBITOR 2;BMS 202;BMS202 PD-1/PD-L1 inhibitor 2(BMS-202) CS-2416 N-{2-[({2-methoxy-6-[(2-methyl-3-phenylphenyl)methoxy]pyridin-3-yl}methyl)amino]ethyl}acetamide PD1 INHIBITOR 2;PD 1 INHIBITOR 2;BMS202;BMS 202 BMS202 (PD-1/PD-L1 inhibitor 2) N-(2-(((2-Methoxy-6-((2-methyl-[1,1'-biphenyl]-3-yl)methoxy)pyridin-3-yl)methyl)amino)ethyl)acetamide 1675203-84-5