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TPCK

TPCK Structure
CAS No.
402-71-1
Chemical Name:
TPCK
Synonyms
TPCK;L-TPCK;TOS-PHE-CMK;Tos-L-Phe-CMK;TPCK USP/EP/BP;(-)-p-toluenesulfonamid;Tos-L-Phe-Chloromethane;TOS-PHE-CHLOROMETHYLKETONE;N-TOSYL-PHE-CHLOROMETHYLKETONE;Tosylphenylalanylchloromethane
CBNumber:
CB0354828
Molecular Formula:
C17H18ClNO3S
Molecular Weight:
351.85
MOL File:
402-71-1.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:46

TPCK Properties

Melting point 106-108 °C(lit.)
Boiling point 509.9±60.0 °C(Predicted)
Density 1.1350 (rough estimate)
refractive index 1.6100 (estimate)
storage temp. -20°C
solubility DMSO: >10 mg/mL stable for several months at 4°C.
form powder
pka 8.71±0.50(Predicted)
color white
BRN 2895215
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
CAS DataBase Reference 402-71-1
EPA Substance Registry System Benzenesulfonamide, N-[(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl]-4-methyl- (402-71-1)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P280-P302+P352-P305+P351+P338+P310
Hazard Codes  Xi
Risk Statements  37/38-41
Safety Statements  26-36
RIDADR  UN 3335
WGK Germany  3
RTECS  XT5613500
10-19-21
TSCA  Yes
HS Code  29350090
NFPA 704
0
3 0

TPCK price More Price(5)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T4376 N-p-Tosyl-L-phenylalanine chloromethyl ketone ≥97% (TLC), powder 402-71-1 100MG ₹3723.8 2022-06-14 Buy
Sigma-Aldrich(India) T4376 N-p-Tosyl-L-phenylalanine chloromethyl ketone ≥97% (TLC), powder 402-71-1 250MG ₹7328.53 2022-06-14 Buy
Sigma-Aldrich(India) T4376 N-p-Tosyl-L-phenylalanine chloromethyl ketone ≥97% (TLC), powder 402-71-1 1G ₹18478.28 2022-06-14 Buy
Sigma-Aldrich(India) T4376 N-p-Tosyl-L-phenylalanine chloromethyl ketone ≥97% (TLC), powder 402-71-1 5G ₹73122.88 2022-06-14 Buy
Sigma-Aldrich(India) 616387 Nα-Tosyl-Phe Chloromethyl Ketone Irreversible inhibitor of chymotrypsin. 402-71-1 250MG ₹5880 2022-06-14 Buy
Product number Packaging Price Buy
T4376 100MG ₹3723.8 Buy
T4376 250MG ₹7328.53 Buy
T4376 1G ₹18478.28 Buy
T4376 5G ₹73122.88 Buy
616387 250MG ₹5880 Buy

TPCK Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Definition

ChEBI: The N-tosyl derivative of L-phenylalanyl chloromethyl ketone.

Safety Profile

Experimental reproductive effects. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx, SOx, and Cl-.

TPCK Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 137)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6778 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6124 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Alfa Aesar 1 800 209 7001 Maharashtra, India 6913 58 Inquiry
career henan chemical co +86-0371-86658258 15093356674; China 29914 58 Inquiry
Chongqing Chemdad Co., Ltd +86-023-6139-8061 +86-86-13650506873 China 39916 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 26925 58 Inquiry
BOC Sciences 16314854226; +16314854226 United States 19743 58 Inquiry
Dayang Chem (Hangzhou) Co.,Ltd. 571-88938639 +8617705817739 China 52861 58 Inquiry
Nextpeptide Inc +86-0571-81612335 +8613336028439 China 19915 58 Inquiry
L-1-TOSYLAMIDE-2-PHENYLETHYL-CHLOROMETHYL KETONE L-1-P-TOSYLAMINO-2-PHENYLETHYL CHLOROMETHYL KETONE L-1-CHLORO-3-(4-TOSYLAMIDO)-4-PHENYL-2-BUTANONE L-1-CHLORO-3-TOSYLAMIDO-4-PHENYL-2-BUTANONE L-1-4'-TOSYLAMINO-2-PHENYLETHYL CHLOROMETHYL KETONE N-TOSYL-L-PHENYLALANINE CHLOROMETHYL KETONE N-TOSYL-PHE-CHLOROMETHYLKETONE N-TOSYLAMIDE PHENETHYL CHLOROMETHYLKETONE P-TOLUENESULFONYL-L-PHENYLALANINE CHLOROMETHYL KETONE N-ALPHA-TOSYL-PHE CHLOROMETHYL KETONE N-ALPHA-P-TOSYL-L-PHENYLALANINE CHLOROMETHYIKETONE (S)-1-CHLORO-3-TOSYLAMIDO-4-PHENYL-2-BUTANONE (S)-1-CHLORO-4-PHENYL-3-TOSYLAMIDO-2-BUTANONE TOS-PHE-CHLOROMETHYLKETONE TOS-PHE-CMK TOSYL-L-PHENYLALANINE CHLOROMETHYL KETONE TOSYL-L-PHENYLALANYL-CHLOROMETHANE TPCK (-)-p-toluenesulfonamid l-1-tosylamido-2-phenylethylchloromethylketone N-Tosyl-L-phenylalanine Chloromethyl Ketone(TPCK) L-1-CHLORO-3-TOSYLAMIDO-4-PHENYL-2-BUTANONE RESEARCH GRADE TPCK (N-TOSYL-L-PHENYLALANINE CHLOROMETH YL KETONE) \ PROTEASE INHIBITOR N-p-Tosyl-L-phenylalanine chloromethyl ketone,(S)-1-Chloro-3-tosylamido-4-phenyl-2-butanone, (S)-1-Chloro-4-phenyl-3-tosylamido-2-butanone, TPCK, Tosyl-L-phenylalanyl-chloromethane N-(p-Toluenesulfonyl)-L-phenylalanyl ChloroMethyl Ketone (S)-N-(4-Chloro-3-oxo-1-phenyl-2-butyl)-p-toluenesulfonamide N-Tosyl-L-phenylalanyl Chloromethyl Ketone TPCK N-α-Tosyl-L-phenylalanylchloromethane TPCK (Tosyl Phenylalanyl ChloroMethyl ketone Chloro-3-tosylaMido-4-phenyl-2-butanone research grade N- (p-toluenesulfonyl) -L- phenylalanyl chloride ketone (TPCK) alpha-N-Tosyl-L-phenylalanine chloromethyl ketone N-alpha-Tosyl-L-phenylalanylchloromethane Tosylphenylalanylchloromethane N-p-Tosyl-L-phenylalanine chloromethyl ketone (TPCK) N-(p-Toluenesulfonyl)-L-phenylalanine chloromethyl ketone L-1-4'-Tosylamino-2-phenylethylechloromethyleketone N-tosyl-L-phenylalanyl chloromethyl ketone Tos-L-Phe-CMK Tosyl-L-Phenylalanine chloromethylketone≥ 98% (TLC) (S)-1-Chloro-3-tosylamido-4-phenyl-2-butanone, (S)-1-Chloro-4-phenyl-3-tosylamido-2-butanone, Tosyl-L-phenylalanyl-chloromethane, TPCK N-[(S)-α-(Chloroacetyl)phenethyl]-4-methylbenzenesulfonamide N-p-Tosyl-L-phenylalanyl chloromethane N-p-Tosyl-L-phenylalanyl chloromethyl ketone Tos-L-Phe-Chloromethane L-1-4'-Tosylamino-2-phenylethyl chloromethyl ketoneTPCK l-n-(alpha-(chloroacetyl)phenethyl)-p-toluenesulfonamide tosylphenylalanylchloromethylketone L-chloromethyl (2-phenyl-1-(p-toluenesulphonylamino)ethyl) ketone L-1-P-TOSYLAMINO-2-PHENYLETHYL CHLORO-METHYL KETONE, 99+% L-1-4'-Tosylamino-2-phenylethyl chloromethyl ketone, 99+% Chloro-3-tosylamido-4-phenyl-2-butanone Benzenesulfonamide, N-(1S)-3-chloro-2-oxo-1-(phenylmethyl)propyl-4-methyl- n-p-tosyl-l-phenylalanine chloromethyl ketone L-1-4-Tosylamido-2-phenylethyl chloromethyl ketone. L-1-PARA-TOSYLAMINO-2-PHENYLETHYLCHLOROMETHYLKETONE L-1-TOSYLAMIDO-2-PHENYLETHYLCHLOROETHYLKETONE NALPHA-(4-Toluenesulfonyl)-L-phenylalanine chloromethyl ketone TOSYL-L-PHENYLALANINE-CHLOROMETHYL KETONE (TPCK)