L-xylose
- CAS No.
- 609-06-3
- Chemical Name:
- L-xylose
- Synonyms
- XYLOSE;L-(-)-XYLOSE;(2S,3R,4S)-2,3,4,5-Tetrahydroxypentanal;L-XYL;L-XYLOSE;XYLOSE, L;L-Xylose,99%;laevo-xylose;L-Xylose (9CI);L(-)XYLOSE 99%
- CBNumber:
- CB0357344
- Molecular Formula:
- C5H10O5
- Molecular Weight:
- 150.13
- MOL File:
- 609-06-3.mol
- Modify Date:
- 2023/5/25 18:00:56
| Melting point | 150-152 °C(lit.) |
|---|---|
| Boiling point | 191.65°C (rough estimate) |
| Density | 1.525 |
| refractive index | -20 ° (C=10, H2O) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | H2O: 0.1 g/mL, clear, colorless |
| pka | 12.46±0.20(Predicted) |
| form | Crystalline Powder |
| color | White to off-white |
| optical activity | [α]24/D 18.7°, c = 4 in H2O |
| Water Solubility | within almost transparency |
| Sensitive | Hygroscopic |
| BRN | 1723080 |
| InChIKey | SRBFZHDQGSBBOR-VVZXFQNISA-N |
| LogP | -2.390 (est) |
| CAS DataBase Reference | 609-06-3(CAS DataBase Reference) |
| EPA Substance Registry System | L-Xylose (609-06-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29400000 | |||||||||
| NFPA 704 |
|
L-xylose price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 851590 | L-(−)-Xylose, mixture of anomers ≥99% | 609-06-3 | 5G | ₹2143.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 851590 | L-(−)-Xylose, mixture of anomers ≥99% | 609-06-3 | 25G | ₹11030.68 | 2022-06-14 | Buy |
| TCI Chemicals (India) | X0021 | L-(-)-Xylose | 609-06-3 | 5G | ₹2100 | 2022-05-26 | Buy |
| TCI Chemicals (India) | X0021 | L-(-)-Xylose | 609-06-3 | 25G | ₹10000 | 2022-05-26 | Buy |
| ottokemi | X 1296 | L-Xylose 99% | 609-06-3 | 1gm | ₹1602 | 2022-05-26 | Buy |
L-xylose Chemical Properties,Uses,Production
Chemical Properties
L-Xylose is a white fine crystalline powder. It is an aldopentose that has a molecular formula C5H10O5 and a molar mass of 150.13 g/mol. The structure of L-xylose is presented in Figure 1. The optical rotations of D- and L-xylose are α20D = -18.6° and α20D = +18.6°, respectively (Fischer and Ruff, 1900). L-Xylose can exist in open chain form, as a pyranose or as a furanose. The relative concentrations of different stereoisomers have not been specified for L-xylose. However, for D-xylose the distribution of different forms in water are: 36.5% α-pyranose, 6% β-pyranose and less than 1 % in open chain and furanose form (Pastinen, 2000). Most likely L-xylose acts similarly to its enantiomer, and thus pyranose rings are predominant.
Figure 1. Structure of L-xylose A) as a Fischer projection, B) as a ball and stick model in acyclic form and C) as a ball and stick model in pyranose ring form.
Uses
L-Xylose is used in the synthesis of L-Xylose derivatives as selective sodium-dependent glucose cotransporter 2 (SGLT2) inhibitors for the treatment of type 2 diabetes.
Definition
ChEBI: Aldehydo-L-xylose is a xylose of ring-opened form having L-configuration.
Application
l-Xylose is a suitable starting material for the production of L-ribonucleosides. L- Xylose can be converted into an L-ribose derivative via oxidation and reduction steps. This product is then glycosylated to give L-ribonucleosides: L-uridine, L-cytidine, L- adenosine and L-guanosine (Moyroud and Strazewski, 1999; Chelain et al., 1995).
L-Xylose can also be used as a starting material for the production of polyhydroxypyrrolidines and related analogues. These compounds have many biological activities. They are shown to have anti-HIV effects, inhibit tumor growth, and also act as ?- and ?-glucosidase inhibitors, which is of relevance for the development of diabetes drugs (Behr and Guillerm, 2007).
Preparation
L-Xylose can be produced from L-xylulose by isomerization. This can be achieved either enzymatically or chemically under alkaline conditions. The equilibrium of the reaction between D-xylose and D-xylulose in an aqueous solution has been determined at pH 6.8-7.4 and at 25 °C to be 85:15 in favor of D-xylose (Tewari et al., 1985).
L-xylose Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Otto Chemie Pvt. Ltd. | +91 9820041841 | Mumbai, India | 5873 | 58 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Souvenier Chemicals | 08048372762Ext 645 | Mumbai, India | 396 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
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