DULCIN
- CAS No.
- 150-69-6
- Chemical Name:
- DULCIN
- Synonyms
- 1-(4-Ethoxyphenyl)urea;Dulcine;Valzin;Sucrol;DULCIN;Dulein;NSC 1839;Suesstoff;D-DULCINE;GLYCOSINE
- CBNumber:
- CB0363233
- Molecular Formula:
- C9H12N2O2
- Molecular Weight:
- 180.2
- MOL File:
- 150-69-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/10/27 15:37:12
| Melting point | 160-161℃ |
|---|---|
| Boiling point | 313.03°C (rough estimate) |
| Density | 1.199 |
| refractive index | 1.5373 (estimate) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| Water Solubility | 1.21g/L(21 ºC) |
| λmax | 289nm(EtOH)(lit.) |
| Merck | 14,3464 |
| LogP | 1.005 (est) |
| CAS DataBase Reference | 150-69-6 |
| IARC | 3 (Vol. 12, Sup 7) 1987 |
| EPA Substance Registry System | Dulcin (150-69-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| RTECS | YT2275000 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2924190090 | |||||||||
| NFPA 704 |
|
DULCIN price More Price(2)
DULCIN Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
Dulcin is a non-nutritive sweetener. Dulcin is a sweet analgesic for use in medical procedures or treatments.
Production Methods
4-Ethoxyphenylurea, dulcin, is produced from the addition of potassium cyanate to p-phenetidine hydrochloride in aqueous solution at room temperature or from mixing urea and p-phenetidine hydrochloride to a mixture of hydrochloric acid and glacial acetic acid.
General Description
White crystals.
Air & Water Reactions
Partially decomposes on heating in water; hydrolyzes in 0.1 N acetic acid. Slightly water soluble .
Reactivity Profile
DULCIN is an example of an amide. Amides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).
Safety Profile
Human poison by ingestion. Moderately toxic experimentally by ingestion. Human systemic effects by ingestion: somnolence, hallucinations, distorted perceptions, and changes in motor activity. In adults 20 to 40 g produces dizziness, nausea, methemoglobinemia, cyanosis, and hypotension. Questionable carcinogen with experimental tumorigenic data. When heated to decomposition it emits toxic fumes of NOx.
DULCIN Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SL Drugs and Pharmaceuticals Pvt. Ltd. | +91 (40) 6661-1133 | New Delhi, India | 2688 | 50 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | China | 2169 | 58 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30253 | 58 | Inquiry |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | China | 34571 | 58 | Inquiry |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23556 | 58 | Inquiry |
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