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CODEINE PHOSPHATE

CODEINE PHOSPHATE Structure
CAS No.
41444-62-6
Chemical Name:
CODEINE PHOSPHATE
Synonyms
CODEINE PHOSPHATE;CODEINEPHOSPHATE,USP;Codeine (phosphate hydrate);Codein phosphate hemihydrate;Codeine Phosphate (CII), USP;CODEINE PHOSPHATE HEMIHYDRATE;Codeine Phosphate CII (100 mg);N-METHYLNORCODEINE HEMIHYDRATE;CODEINIUM PHOSPHATE HEMIHYDRATE;Codeine·phosphoric acid·0.5hydrate
CBNumber:
CB0417831
Molecular Formula:
C18H24NO7P
Molecular Weight:
397.36
MOL File:
41444-62-6.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:02:58
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CODEINE PHOSPHATE Properties

solubility Freely soluble in water, slightly soluble or very slightly soluble in ethanol (96 per cent).
form A crystalline solid
BCS Class 3
CAS DataBase Reference 41444-62-6

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS06
Signal word  Danger
Hazard statements  H301-H361-H334-H317
Precautionary statements  P201-P202-P281-P308+P313-P405-P501-P261-P285-P304+P341-P342+P311-P501-P261-P272-P280-P302+P352-P333+P313-P321-P363-P501-P264-P270-P301+P310-P321-P330-P405-P501
HS Code  2939110000
NFPA 704
0
2 0

CODEINE PHOSPHATE Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder or small, colourless crystals.

Uses

Antitussive; analgesic (narcotic).

Clinical Use

Codeine is used extensively to treat moderate to mild pain. Codeine is a weak μ agonist, but approximately 10% of an oral dose (30–60 mg) is metabolized to morphine, which contributes significantly to its analgesic effect. The plasma half-life of codeine after oral dose is 3.5 hours. The dose of codeine needed to produce analgesia after parenteral dose causes releases of histamine sufficient to produce hypotension, pruritus, and other allergic responses. Thus, administration of codeine by parenteral route is not recommended.

CODEINE PHOSPHATE Preparation Products And Raw materials

Raw materials

Trimethylphenylammonium chloride Sodium hydroxide MORPHINE

Preparation Products

41444-62-6(CODEINE PHOSPHATE)Related Search:

NOSCAPINE HYDROCHLORIDE S-Carboxymethyl-L-cysteine CODEINE CODEINE PHOSPHATE PHOLCODINE IMP. B (PHARMEUROPA) AS PHOSPHATE HEMIHYDRATE: CODEINE PHOSPHATE HEMIHYDRATE[CONTROLLED SUBSTANCE]
CODEINE PHOSPHATE, DIHYDRATE) Codeine phosphate (6CI, 7CI),Codeine phosphate (1:1) HYDROCODONE HYDROGEN TARTRATE 2.5-HYDRATEIMP. C (EP) AS PHOSPHATE HEMIHYDRATE:CODEINE PHOSPHATE HEMIHYDRATE[CONTROLLED SUBSTANCE] CODEINE PHOSPHATE, SEQUIHYDRATE) ETHYLMORPHINE HYDROCHLORIDE IMP. C (EP) AS PHOSPHATE HEMIHYDRATE: CODEINE PHOSPHATE HEMIHYDRATE [CONTROLLED SUBSTANCE]
CODEINE PHOSPHATE HEMIHYDRATE [CONTROLLED SUBSTANCE] MORPHINE HYDROCHLORIDE IMP. A (EP) AS PHOSPHATE HEMIHYDRATE: CODEINE PHOSPHATE HEMIHYDRATE[CONTROLLED SUBSTANCE] MORPHINE SULPHATE IMP. A (EP) AS PHOSPHATE HEMIHYDRATE: CODEINE PHOSPHATE HEMIHYDRATE[CONTROLLED SUBSTANCE] acecobarb migraleve
6-O-METHYLCODEINE PHOSPHATE Codeine phosphate sesquihydrate
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CODEINE PHOSPHATE CODEINE PHOSPHATE HEMIHYDRATE CODEINIUM PHOSPHATE HEMIHYDRATE METHYLMORPHINE PHOSPHATE HEMIHYDRATE N-METHYLNORCODEINE HEMIHYDRATE MORPHINE-3-METHYL ETHER HEMIHYDRATE Morphinan-6-ol, 7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-, (5.alpha.,6.alpha.)-, phosphate (salt), hydrate (2:2:1) CODEINEPHOSPHATE,USP Codein phosphate hemihydrate Codeine·phosphoric acid·0.5hydrate Codeine Phosphate CII (100 mg) Codeine Phosphate (CII), USP Codeine (phosphate hydrate) Dihydrocodeine Hydrogen Tartrate Impurity A as Phosphate Hemihydrate Morphine Hydrochloride Impurity A as Phosphate Hemihydrate Pholcodine Monohydrate Impurity B as Phosphate Hemihydrate Dihydrocodeine Hydrogen Tartrate EP Impurity A as Phosphate Hemihydrate 41444-62-6 C18H21NO3H2OH3O4P API