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N-Acetyl-L-proline

CAS No.: 68-95-1

Chemical Name:: N-Acetyl-L-proline

Synonyms: AC-PRO-OH;NSC 280718;AC-PROLINE;N-AC-L-PRO;N-Ac-Pro-OH;Ac-L-Pro-Oh;N-Acetyl-Pro;AC-PYRD(2)-OH;Acetylproline;N-ACETYL-L-PRO

CBNumber:: CB0481658

Molecular Formula:: C7H11NO3

Molecular Weight:: 157.17

MOL File:: 68-95-1.mol

MSDS File:: SDS

Modify Date:: 2024/6/4 15:29:52

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N-Acetyl-L-proline Properties

Melting point	115-117 °C
alpha	-86 º (c=1 EtOH)
Boiling point	366.2±35.0 °C(Predicted)
Density	1.274±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform (Slightly), Methanol (Slightly), Water (Slightly)
pka	3.69±0.20(Predicted)
form	Powder
color	White to off-white
BRN	83200
InChI	InChI=1S/C7H11NO3/c1-5(9)8-4-2-3-6(8)7(10)11/h6H,2-4H2,1H3,(H,10,11)/t6-/m0/s1
InChIKey	GNMSLDIYJOSUSW-LURJTMIESA-N
SMILES	C(O)(=O)[C@@H]1CCCN1C(C)=O
CAS DataBase Reference	68-95-1(CAS DataBase Reference)
NIST Chemistry Reference	L-proline, 1-acetyl-(68-95-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P280-P301+P312-P302+P352-P305+P351+P338

Hazard Codes

Safety Statements

24/25

WGK Germany

HazardClass

IRRITANT

HS Code

29339900

NFPA 704

	1
0		0

N-Acetyl-L-proline price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	A0783	N-Acetyl-L-proline	68-95-1	1G	₹3810.4	2022-06-14	Buy
Sigma-Aldrich(India)	A0783	N-Acetyl-L-proline	68-95-1	5G	₹11658.53	2022-06-14	Buy
SRL	90430	N-Acetyl-L-Proline extrapure, 98%	68-95-1	5Gms	₹1560	2022-05-26	Buy
SRL	90430	N-Acetyl-L-Proline extrapure, 98%	68-95-1	25Gms	₹5880	2022-05-26	Buy
SRL	90430	N-Acetyl-L-Proline extrapure, 98%	68-95-1	100Gms	₹15640	2022-05-26	Buy

Product number	Packaging	Price	Buy
A0783	1G	₹3810.4	Buy
A0783	5G	₹11658.53	Buy
90430	5Gms	₹1560	Buy
90430	25Gms	₹5880	Buy
90430	100Gms	₹15640	Buy

N-Acetyl-L-proline Chemical Properties,Uses,Production

Chemical Properties

white to off-white powder

Uses

N-Acetyl-L-proline is an aminoacid used in the synthesis of pharmaceutical compounds useful in preventing and treating disorders and syndromes associated with the nervous, vascular, musculoskeletal, o r cutaneous systems.

Biochem/physiol Actions

N-acetyl-L-proline is an analog of the COOH-terminal dipeptide portion of preferred substrates of angiotensin-converting enzyme (ACE). It may be used in studies of the binding of substrates and inhibitors by ACE and to differentiate the specificities of various aminoacylases.

References

[1] Jingxuan Qiu. “Solubility Behavior and Polymorphism of N-Acetyl-l-proline in 16 Individual Solvents from 283.15 to 323.15 K.” Journal of Chemical & Engineering Data 66 3 (2021): 1533–1542.

Description

N-Acetyl-L-proline (NALP) is an N-acetyl derivative of L-proline, which has wide application in medicine and is commonly utilized as a biologically active supplement. It can also act as an intermediate for synthesizing pharmaceuticals for preventing and treating some disorders and syndromes associated with the nervous, vascular, musculoskeletal, or cutaneous systems. In laboratories, it could play the role of a simple model for the secondary structure of proline-containing peptides. NALP can be acetylated from L-proline via a standard method, in the environment of acetic acid, or by the action of acetic anhydride on aqueous solutions of the products of the alkaline hydrolysis of gelatin followed by extraction. However, these methods may result in the production of many byproducts[1].

N-Acetyl-L-proline Preparation Products And Raw materials

Raw materials

Preparation Products

N-Acetyl-L-proline Suppliers

Global( 351)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ADVENT CHEMBIO PRIVATE LIMITED	+91-9821524116 +91-9821524116	Mumbai, India	353	58	Inquiry
TEADUS PHARMA PRIVATE LIMITED	+91-9740077663 +91-9740077663	Telangana, India	242	58	Inquiry
SV CHEM INTERMEDITES PRIVATE LIMITED	+91-9940629423 +91-9940629423	Tamil Nadu, India	202	58	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
Arnavi Laboratory	+91-7780703633 +91-7780703633	Telangana, India	83	58	Inquiry
ALS INDIA LIFE SCIENCES	+91-8977036379 +91-8977036379	Hyderabad, India	1879	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
Gm-chemsys	+91 9989450512	New Delhi, India	42	50	Inquiry
Santo Righello Pvt. Ltd	91-9885571757	Hyderabad, India	919	58	Inquiry
Anand Agencies	91-20-24454597	Maharashtra, India	2337	58	Inquiry

Supplier	Advantage
ADVENT CHEMBIO PRIVATE LIMITED	58
TEADUS PHARMA PRIVATE LIMITED	58
SV CHEM INTERMEDITES PRIVATE LIMITED	58
JSK Chemicals	58
Arnavi Laboratory	58
ALS INDIA LIFE SCIENCES	58
CHEMSWORTH	30
Gm-chemsys	50
Santo Righello Pvt. Ltd	58
Anand Agencies	58

68-95-1(N-Acetyl-L-proline)Related Search:

N-Acetyl-L-cysteine L-Proline cis-4-Hydroxy-L-proline Acetylacetone Acetyl chloride

D-Proline L-PROLINE-(4-3H(N)) N-Acetyl-L-valine AC-TYR-NH2 N-ALPHA-ACETYL-D-PROLINE,N-ACETYL-D-PROLINE,ACETYL-D-PROLINE

Fosinopril sodium 4β-Cyclohexyl-1-[[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline,(4S)-4-Cyclohexyl-1-[2-[hydroxy(4-phenylbutyl)phosphinyl]acetyl]-L-proline Disodium Salt Fosinopril N-ALPHA-ACETYL-L-PROLINE AMIDE,ACETYL-L-PROLINE AMIDE N6-Trifluoroacetyl-L-lysyl-L-proline

1-ACETYLPYRROLIDINE 1-[(7-Methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-proline tert-Butyl Ester,7-Methoxycoumarin-4-Acetyl-L-proline tert-Butyl Ester (4S)-4-Cyclohexyl-1-[2-[hydroxy(4-phenyl-d5-butyl)phosphinyl]acetyl]-L-proline Sodium Salt

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N-AN-Acetyl-L-prolineN-Acetyl-L-prolinecetyl-L-proline (2S)-1-acetyl-2-pyrrolidinecarboxylate (S)-N-Acetylproline L-N-Acetylproline NSC 280718 N-Ac-Pro-OH ASINEX-REAG BAS 16579166 ACETYL-L-PROLINE AC-PYRD(2)-OH AC-PROLINE AC-PRO-OH N-ALPHA-ACETYL-L-PROLINE N-ALPHA-ACETYL-L-PYRROLIDINE-2-CARBOXYLIC ACID N-ACETYL-L-PRO N-ACETYL-L-PROLINE N-AC-L-PRO (S)-1-ACETYL-PYRROLIDINE-2-CARBOXYLIC ACID 1-Acetylproline Acetylproline L-Proline, 1-acetyl- Proline, 1-acetyl-, L- 1-acetyl-L-proline Ac-L-Pro-Oh L-Proline, 1-acetyl- (9CI) (S)-Acetyl-pyrrolidine-2-carboxylic acid Acetyl-L-proline99% N-ACETYL-L-PROLINE (N-AC-L-PRO) N-alpha-Actetyl-L-proline N-Acethyl-L-proline (+/-)-(3-Methoxy-4-hydroxyphenyl)-2-isopropylaminoethanol hydrochloride Benzenemethanol, 4-hydroxy-3-methoxy-a-[[(1-methylethyl)amino]methyl]-, hydrochloride Vanillyl alcohol, a-[(isopropylamino)methyl]-, hydrochloride (2S)-1-Acetylpyrrolidine-2α-carboxylic acid N-Acetyl-L-proline,99% N-ACETYL-L-PROLINE (USP) Ac-Pro-OH ,≥99% (S)-(-)-N-Acetylproline N-Acetyl-L-proline, 99% 1GR l-proline n-acetyl N-Acetyl-L-proline USP/EP/BP N-Acetyl-L-Proline extrapure, 98% N-Acetyl-Pro 68-95-1 C7H10NO3 CARBOXYLIC ACID Modified Amino Acids Biochemicals and Reagents BioChemical A - H Amino Acids and Peptides A - H Amino Acids Modified Amino Acids Amino Acid Derivatives Amino Acids chiral N-Acetyl-Amino acid series amino