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cis-4-Hydroxy-L-proline

CAS No.: 618-27-9

Chemical Name:: cis-4-Hydroxy-L-proline

Synonyms: (2S,4S)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID;H-CIS-HYP-OH;CIS-4-HYDROXYPROLINE;CIS-HYP-OH;cis-Hydroxy-L-proline;(4S)-4-hydroxypyrrolidine-2-carboxylic acid;CHYP;cis L;cis-L-Hyp-OH;H-L-CIS-HYP-OH

CBNumber:: CB6158895

Molecular Formula:: C5H9NO3

Molecular Weight:: 131.13

MOL File:: 618-27-9.mol

MSDS File:: SDS

Modify Date:: 2023/11/24 16:35:22

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cis-4-Hydroxy-L-proline Properties

Melting point	257 °C (dec.) (lit.)
alpha	-59 º (c=2, H2O)
Boiling point	242.42°C (rough estimate)
Density	1.3121 (rough estimate)
refractive index	-59 ° (C=2, H2O)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	soluble
form	Powder
pka	2.14±0.40(Predicted)
color	White to beige
Water Solubility	soluble
Merck	14,4840
BRN	81440
InChIKey	PMMYEEVYMWASQN-IMJSIDKUSA-N
CAS DataBase Reference	618-27-9(CAS DataBase Reference)
EPA Substance Registry System	L-Proline, 4-hydroxy-, (4S)- (618-27-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

24/25-36/37/39-27-26

WGK Germany

TSCA

Yes

HS Code

29339900

NFPA 704

	1
1		0

cis-4-Hydroxy-L-proline price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	H1637	cis-4-Hydroxy-L-proline collagen synthesis inhibitor	618-27-9	50MG	₹6397.58	2022-06-14	Buy
Sigma-Aldrich(India)	H1637	cis-4-Hydroxy-L-proline collagen synthesis inhibitor	618-27-9	250MG	₹17384.95	2022-06-14	Buy
Sigma-Aldrich(India)	H1637	cis-4-Hydroxy-L-proline collagen synthesis inhibitor	618-27-9	1G	₹57675.6	2022-06-14	Buy
TCI Chemicals (India)	H1169	cis-4-Hydroxy-L-proline	618-27-9	100MG	₹5700	2022-05-26	Buy
TCI Chemicals (India)	H1169	cis-4-Hydroxy-L-proline	618-27-9	1G	₹6900	2022-05-26	Buy

Product number	Packaging	Price	Buy
H1637	50MG	₹6397.58	Buy
H1637	250MG	₹17384.95	Buy
H1637	1G	₹57675.6	Buy
H1169	100MG	₹5700	Buy
H1169	1G	₹6900	Buy

cis-4-Hydroxy-L-proline Chemical Properties,Uses,Production

Chemical Properties

White to beige powder

Uses

cis-4-Hydroxy-L-proline (CHP) is a proline analog that inhibits collagen synthesis and has been used as an anticancer compound. CHP blocked myotube formation and expression of sarcomeric myosin heavy chain in C2C12 murine skeletal muscle cells. CHP inhibited proliferation of murine Panc02 pancreatic carcinoma cell line3 and rat pancreatic carcinoma cell line DSL6A. cis-4-Hydroxy-L-proline and other hydrosyl-L-prolines are important intermediates for chiral synthesis of potential drugs.

Definition

ChEBI: L-Proline in which a hydrogen at the 4-position of the pyrrolidine ring is substituted by a hydroxy group (S-configuration).

cis-4-Hydroxy-L-proline Preparation Products And Raw materials

Raw materials

L-Proline, 4-hydroxy-, ethyl ester, (4S)- (9CI) 1,2-Pyrrolidinedicarboxylic acid, 4-(formyloxy)-, 2-methyl 1-(phenylmethyl) ester, (2S-cis)- (9CI) N-Boc-cis-4-Hydroxy-L-proline （2s，4r）-1，2-dicarbobenzyloxy-4-hydroxypyrrolidine N-Cbz-Hydroxy-L-proline

Z-CIS-HYP-OH （2s，4s）-dibenzyl 4-hydroxypyrrolidine-1，2-dicarboxylate Z-HYP-OME L-Hydroxyproline

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Preparation Products

Fomc-cis-L-hydroxyproline-OH 4-HYDROXY-1-(TOLUENE-4-SULFONYL)-PYRROLIDINE-2-CARBOXYLIC ACID

cis-4-Hydroxy-L-proline Suppliers

Global( 339)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Suven Pharmaceuticals Limited	+91-91-40-23541142 +91-4023541142	Telangana, India	218	58	Inquiry
ARRKEM LIFE SCIENCES PRIVATE LIMITED	+91-8148739767 +91-8148739767	Telangana, India	260	58	Inquiry
Tulasi Labs	+91-8106722317 +91-8106722317	Telangana, India	44	58	Inquiry
Clearsynth Labs	91-22-45045900	Maharashtra, India	3889	58	Inquiry
Maas Pharma Chemicals	+91-9958666224	Delhi, India	1607	58	Inquiry
CHEMSWORTH	+91-261-2397244	New Delhi, India	6707	30	Inquiry
A.J Chemicals	91-9810153283	New Delhi, India	6124	58	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
TCI Chemicals (India) Pvt. Ltd.	1800 425 7889	New Delhi, India	6778	58	Inquiry
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	China	29798	60	Inquiry

Supplier	Advantage
Suven Pharmaceuticals Limited	58
ARRKEM LIFE SCIENCES PRIVATE LIMITED	58
Tulasi Labs	58
Clearsynth Labs	58
Maas Pharma Chemicals	58
CHEMSWORTH	30
A.J Chemicals	58
CLEARSYNTH LABS LTD.	58
TCI Chemicals (India) Pvt. Ltd.	58
Capot Chemical Co.,Ltd.	60

cis-4-Hydroxy-L-proline Spectrum

cis-4-Hydroxy-L-proline(618-27-9)MS cis-4-Hydroxy-L-proline(618-27-9)¹HNMR cis-4-Hydroxy-L-proline(618-27-9)¹³CNMR cis-4-Hydroxy-L-proline(618-27-9)IR1 cis-4-Hydroxy-L-proline(618-27-9)IR2 cis-4-Hydroxy-L-proline(618-27-9)Raman

618-27-9(cis-4-Hydroxy-L-proline)Related Search:

CIS-4-HYDROXY-L-PROLINE METHYL ESTER HCL,CIS-4-HYDROXY-L-PROLINE METHYL ESTER HYDROCHLORIDE D-Proline L-PROLINE-(4-3H(N)) L-Proline CHLOROPHOSPHONAZO III

cis-4-Hydroxy-D-proline hydrochloride,CIS-4-HYDROXY-D-PROLINE HCL CIS-4-HYDROXY-D-PROLINE (4S)-4-hydroxy-L-proline hydrochloride cis-4-Hydroxycyclohexanecarboxylic acid Cyclohexanecarboxylic acid, 4-hydroxy-, Methyl ester, cis-

cis-4-Methoxy-cyclohexylamine hydrochloride cis-4-AMinocyclohexaneMethanol hydrochloride 4-(Dimethylamino)cyclohexanol CIS-4-HYDROXY-D-PROLINE METHYL ESTER L-Hydroxyproline

N-Boc-cis-4-Hydroxy-L-proline methyl ester N-ALPHA-BUTOXYCARBONYL-CIS-4-HYDROXY-L-PROLINE,N-BOC-CIS-4-HYDROXY-L-PROLINE,N-T-BOC-CIS-4-HYDROXY-L-PROLINE,BOC-CIS-4-HYDROXY-L-PROLINE N-Cbz-Hydroxy-L-proline

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(S)-Allo-hydroxyproline cis-4-Hydroxy-L-proline collagen synthesis inhibitor L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLIC ACID L-ALLO-4-HYDROXY-2-PYRROLIDINECARBOXYLLIC ACID L-ALLO-HYDROXYPROLINE CIS-4-HYDROXY-L-PROLINE CIS-L-4-HYDROXYPROLINE CIS-HYDROXYPROLINE CHYP HYDROXY-L-PROLINE [ALLO] H-PRO(CIS-4-OH)-OH H-L-CIS-HYP-OH cis-4-Hydroxy-L-proline, 97.0%(T) cis-L-4-Hydroxyproline≥ 99% (NMR) cis-L-Hyp-OH cis-4-Hydroxy-L-proline Hydrochloride,99%e.e. cis-4-Hydroxy-L-proline Vetec(TM) reagent grade, 98% CIS-4-HYDROXY-L-PROLINE HYDROLORIDE L-CIS-4-HYDROXYPROLINE L-CIS-HYDROXYPROLINE (2S,4S)-(-)-4-HYDROXY-2-PYRROLINECARBOXYLIC ACID ALLO-4-HYDROXY-L-PROLINE cis-4-L-Hydroxyproline (2S,4S)-(-)-4-Hydroxypyrrolidin-2-ylcarboxylic acid CIS-4-HYDROXY-L-PROLINE NATURAL ISOMER -ALLO-HYDROXYPROLINE 4-CIS-HYDROXYPROLINE L-CIS-HYDROXYPROLINE, (2S,4S)-(-)-4-HYDROXY-2-PYRROLINECARBOXYLIC ACID (2S,4S)-4-HYDROXY-L-PROLINE (2S)-4α-Hydroxy-2α-pyrrolidinecarboxylic acid (4S)-4-Hydroxy-L-proline cis-4-Hydroxy-L-proline,99% Cis-4-Hydroxy-L-proline methyl ester (2S,4S)-4-hydroxypyrrolidine-2-carboxylic acid hydrochloride Cis-4-hydroxy-L-proline Hyadrochloride (2S,4S)-4-Hydroxyproline (2S,4S)-(-)-4-Hydroxypyrrolidine-2-carboxylic acid 97% cis-4-Hydroxy-L-proline USP/EP/BP L-Proline, 4-hydroxy-, (4S)- cis-4-Hydroxy-L cis-4-Hydroxy-L-proline> cis L CIS-HYP-OH H-CIS-HYP-OH (4S)-4-hydroxypyrrolidine-2-carboxylic acid (2S,4S)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID CIS-4-HYDROXYPROLINE cis-Hydroxy-L-proline proline,collagen,Inhibitor,cis4HydroxyLproline,tumor,cis 4 Hydroxy L proline,inhibit,Endogenous Metabolite,fibroblast Coclaurine Impurity 4 618-27-9 618-21-7 Specialty Synthesis Proline Derivatives Peptide Synthesis Unnatural Amino Acid Derivatives Amino Acids Biochemistry