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Fosinopril sodium

Fosinopril sodium Structure
CAS No.
88889-14-9
Chemical Name:
Fosinopril sodium
Synonyms
MONOPRIL;DYNACIL;ELIDIUR;FOSINORM;Acecor-d5;Staril-d5;TENSOZIDE;Eosinopril;SQ 28555-d5;Secorvas-d5
CBNumber:
CB5110597
Molecular Formula:
C30H46NNaO7P
Molecular Weight:
586.65
MOL File:
88889-14-9.mol
Modify Date:
2023/6/8 9:02:51
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Fosinopril sodium Properties

Melting point 196-198°C
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility H2O: >20mg/mL
form powder
color white to off-white
CAS DataBase Reference 88889-14-9(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08
Signal word  Warning
Hazard statements  H319-H361d
Precautionary statements  P202-P264-P280-P305+P351+P338-P308+P313-P337+P313
WGK Germany  3
HS Code  2933995300
NFPA 704
0
2 0

Fosinopril sodium price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) F1308 Fosinopril sodium ≥98% (HPLC), powder 88889-14-9 5MG ₹12849.28 2022-06-14 Buy
Sigma-Aldrich(India) PHR3356 Fosinopril sodium certified reference material, pharmaceutical secondary standard 88889-14-9 500MG ₹22700.03 2022-06-14 Buy
Sigma-Aldrich(India) F1308 Fosinopril sodium ≥98% (HPLC), powder 88889-14-9 25MG ₹50780.08 2022-06-14 Buy
Product number Packaging Price Buy
F1308 5MG ₹12849.28 Buy
PHR3356 500MG ₹22700.03 Buy
F1308 25MG ₹50780.08 Buy

Fosinopril sodium Chemical Properties,Uses,Production

Description

Fosinopril sodium, an ester prodrug of fosinoprilat, is the first of a new generation of phosphinic acid ACE inhibitors indicated for the once-daily treatment of hypertension. Unlike captopril and lisinopril, it is reportedly effective in increasing the left ventricular peak filling rates and peak ejection rates in hypertensive patients at rest. Another advantage is that fosinopril sodium is metabolized equally by renal and hepatic routes, thereby avoiding the requirement to modify dosage in patients with renal insufficiency.

Chemical Properties

White to Off-White Crystalline Solid

Uses

Fosinopril sodium is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.

Definition

ChEBI: The sodium salt of fosinopril. It is used for the treatment of hypertension and heart failure. A pro-drug, its phosphinate ester group is hydrolysed in vivo to give the corresponding phosphininc acid, fosinoprilat, which is the active metaboli e.

General Description

Fosinopril sodium, (4S)-4-cyclohexyl-1-[[[(RS)-1-hydroxy-2-methylpropoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline sodium salt (Monopril),is a phosphorus-containing ACE inhibitor. It is inactive butserves as a prodrug, being completely hydrolyzed by intestinaland liver enzymes to the active diacid fosinoprilat.

Fosinopril sodium Preparation Products And Raw materials

Raw materials

trans-4-Cyclohexyl-L-proline 2-Ethylhexanoic acid Triethylamine Topotecan

Preparation Products

Fosinopril

Fosinopril sodium Suppliers

Global( 276)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Hetero Drugs Limited +91-4023704923 +91-4023704923 Telangana, India 296 58 Inquiry
Alfa Omega Pharma +91-8050045945 +91-9972665399 Maharashtra, India 126 58 Inquiry
Nivon Specialties (India) 91-9323789882 Maharashtra, India 154 58 Inquiry
CLEANCHEM LABORATORIES LLP +91 98921 69560 New Delhi, India 326 58 Inquiry
Medkem Laboratories 91-40-23700606 Andhra Pradesh, India 297 58 Inquiry
Ayon PharmaChem 91-22-28638348 Maharashtra, India 303 58 Inquiry
Euroasia Trans Continental +91 22 56349035-36 New Delhi, India 519 47 Inquiry
Clearsynth Labs 91-22-45045900 Maharashtra, India 3889 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Supplier Advantage
Hetero Drugs Limited 58
Alfa Omega Pharma 58
Nivon Specialties (India) 58
CLEANCHEM LABORATORIES LLP 58
Medkem Laboratories 58
Ayon PharmaChem 58
Euroasia Trans Continental 47
Clearsynth Labs 58
SynZeal Research Pvt Ltd 58
Triveni chemicals 58

88889-14-9(Fosinopril sodium)Related Search:

Sodium carbonate N-ACETYL-L-TYROSINE ETHYL ESTER L-PROLINE-(4-3H(N)) Methanol Diclofenac sodium
Kresoxim-methyl Sodium bicarbonate Methyl acetate Methyl acrylate Sodium hydroxide
Sodium formate Sodium chloride Paraquat dichloride Methylparaben Fosinopril
Sodium acetate Sodium gluconate cis-4-Hydroxy-L-proline
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sodiuM (2S,4S)-4-cyclohexyl-1-(2-((2-Methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylate Sodium (2S,4S)-4-cyclohexyl-1-(2-((2-methyl-1-(propionyloxy)propoxy)-(4-phenylbutyl)phosphoryl)ac MONOPRIL SQ 28555-d5 Staril-d5 Fosinopril sodiuM API Fosinopril-d7 sodiuM salt Acecor-d5 Eosinopril-d5 Monopril-d5 Secorvas-d5 (4S)-4-cyclohexyl-1-[2-[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline,sodium salt (1:1) (2S,4S)-4-Cyclohexyl-1-(2-{[2-methyl-1-(propanoyloxy)propoxy](4-phenylbutyl)phosphoryl}acetyl)pyrrolidine-2-carboxylic acid sodium 4-cyclohexyl-1-[2-[[2-methyl-1-(1-oxopropoxy)propoxy]-(4-phenylbutyl)phosphoryl]-1-oxoethyl]-2-pyrrolidinecarboxylate Fosinopril sodium (Monopril) Sodium (2S,4S)-4-cyclohexyl-1-(2-((2-methyl-1-(propionyloxy)propoxy)-(4-phenylbutyl)phosphoryl TENSOZIDE FOSINOPRIL-D5 SODIUM SALT FOSINOPRIL NA FOSINOPRIL SODIUM FOSINOPRIL SODIUM SALT FOSINORM DYNACIL ELIDIUR (4S)-4-CYCLOHEXYL-1-[[(R)-[(1S)-2-METHYL-1-(1-OXOPROPOXY)PROPOXY](4-PHENYLBUTYL)PHOSPHINYL]ACETYL]-L-PROLINE (4s)-4-cyclohexyl-1-{[(rs)-2-methyl-1-(propionyloxy)propoxy]-(4-phenylbutyl)phosphinylacetyl}-l-proline sodium salt Fosinopril Sodium (200 mg) (4S)-4-Cyclohexyl-1-[[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline SodiuM Salt Eosinopril (4S)-4-Cyclohexyl-1-[[(R)-[(1S)-2-Methyl-1-(1-oxopropoxy)propoxy](4-(phenyl-d5)butyl)phosphinyl]acetyl]-L-proline SodiuM Salt Forsinopril sodium salt 4β-Cyclohexyl-1-[[[(S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline sodium salt Dynacil, Elidiur, Fosinorm, Monopril, Staril, Tensozide, (4S)-4-Cyclohexyl-1-[[(R)-[(1S)-2-methyl-1-(1-oxopropoxy)propoxy](4-phenylbutyl)phosphinyl]acetyl]-L-proline FOSINPRIL SODIUM fosinopril impurity 1 Fosinopril sodium CRS Fosinopril sodium USP/EP/BP Fosinopril sodiumr Sodium (2S,4S)-4-cyclohexyl-1-(2-((R)-((S)-2-methyl-1-(propionyloxy)propoxy)(4-phenylbutyl)phosphoryl)acetyl)pyrrolidine-2-carboxylate Fosinopril Sodium (SQ28555) Fosinopril sodiumQ: What is Fosinopril sodium Q: What is the CAS Number of Fosinopril sodium Q: What is the storage condition of Fosinopril sodium Q: What are the applications of Fosinopril sodium 88889-14-9 C30H45NO7PNa C30H45NNaO7P C30H46NO7PNa 58564 Cardiovascular APIs Intermediates & Fine Chemicals Pharmaceuticals Aromatics Chiral Reagents Phosphorylating and Phosphitylating Agents Isotope Labelled Compounds API