6-Chloro-1-tetralone
- CAS No.
- 26673-31-4
- Chemical Name:
- 6-Chloro-1-tetralone
- Synonyms
- 6-chloro-3,4-dihydronaphthalen-1(2H)-one;6-Chloro-3,4-dihydro-2H-naphthalen-1-one;6-chloro-3;5-CHLORO-1-INDOMONE;5-CHLORO-L-INDOMONE;6-Chloro-α-Tetralone;6-Chloro-1-tetralone;6-CHLORO-TETRAL-1-ON;6-Chloro-tetral-1-one;6-chlorotetralin-1-one
- CBNumber:
- CB0766902
- Molecular Formula:
- C10H9ClO
- Molecular Weight:
- 180.63
- MOL File:
- 26673-31-4.mol
- Modify Date:
- 2024/3/19 13:53:49
| Melting point | 53 °C |
|---|---|
| Boiling point | 150°C/0.7mmHg(lit.) |
| Density | 1.248±0.06 g/cm3(Predicted) |
| refractive index | 1.59 |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| form | powder to lump |
| color | White to Yellow to Orange |
| CAS DataBase Reference | 26673-31-4 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P301+P312+P330 | |||||||||
| HS Code | 2914390090 | |||||||||
| NFPA 704 |
|
6-Chloro-1-tetralone price More Price(3)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | JRD0960 | 6-Chloro-3,4-dihydronaphthalen-1(2H)-one | 26673-31-4 | 1G | ₹29887.83 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C2917 | 6-Chloro-1-tetralone min. 96.0 % | 26673-31-4 | 1G | ₹4500 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C2917 | 6-Chloro-1-tetralone min. 96.0 % | 26673-31-4 | 5G | ₹17000 | 2022-05-26 | Buy |
6-Chloro-1-tetralone Chemical Properties,Uses,Production
Uses
6-Chloro-1-tetralone is a novel and potent intermediate used for synthesis of pharmaceutical compounds.
Synthesis
A solution of sodium nitrite (173 mg, 2.51 mmol) in water (5 mL) at 0 °C (ice-bath) was added to a magnetically stirred suspension of 6-Amino-1-tetralone (360 mg, 2.23 mmol) in aqueous hydrochloric acid (10 mL, 6 M) at 0 °C. This reaction mixture was added dropwise to a solution of copper(I) chloride (267 mg, 2.70 mmol) in concentrated hydrochloric acid (5 mL) at 0 °C. It was allowed to warm up to room 100 temperature and stirred for a further 2 h after which it was neutralised with solid sodium carbonate, extracted with ethyl acetate (3 × 20 mL) and concentrated in vacuo to give slightly yellow oil. This material was subjected to flash chromatography (50% chloroform in hexane) and concentration of the appropriate fractions afforded 6-chloro-1-tetralone (180 mg, 45%) as a waxy solid.
6-Chloro-1-tetralone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| BTC pharm India | +918790379245 | AndhraPradesh, India | 1269 | 58 | Inquiry |
| GLR Innovations | +91 9891111994 | New Delhi, India | 4542 | 58 | Inquiry |
| SIRI LIFE SCIENCES | +91-9000234689 +91-9000234689 | Hyderabad, India | 177 | 58 | Inquiry |
| Dr. Jagath Reddy's Heterocyclics | +91-4065572151 +91-4023773841 | Telangana, India | 162 | 58 | Inquiry |
| CiVentiChem Private Limited | +91-40-23197766 +91-8897000471 | Telangana, India | 126 | 58 | Inquiry |
| Vivera Labs | 91-9912882943 | Hyderabad, India | 24 | 58 | Inquiry |
| Siri Life Sciences Pvt Ltd | +91 9000234689 | Andhra Pradesh, India | 134 | 58 | Inquiry |
| VASIN BIO LIFE SCIENCES PVT LTD | 9491644688 | Hyderabad, India | 2096 | 58 | Inquiry |
| Dr Chindepalli | 91-7036227677 | Hyderabad, India | 486 | 58 | Inquiry |
| Clearsynth Labs | 91-22-45045900 | Maharashtra, India | 3889 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| BTC pharm India | 58 |
| GLR Innovations | 58 |
| SIRI LIFE SCIENCES | 58 |
| Dr. Jagath Reddy's Heterocyclics | 58 |
| CiVentiChem Private Limited | 58 |
| Vivera Labs | 58 |
| Siri Life Sciences Pvt Ltd | 58 |
| VASIN BIO LIFE SCIENCES PVT LTD | 58 |
| Dr Chindepalli | 58 |
| Clearsynth Labs | 58 |
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