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ChemicalBook > Product Catalog >API >Antineoplastic agents >Natural sources of antineoplastic >epothilone E

epothilone E

epothilone E Structure
CAS No.
201049-37-8
Chemical Name:
epothilone E
Synonyms
epothilone E;epothilone E USP/EP/BP;[4S,7R,8S,9S,13R,14S,16S(E)]-13,14-Epoxy-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[2-[2-(hydroxymethyl)thiazol-4-yl]-1-methylvinyl]-1-oxacyclohexadecane-2,6-dione;(1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-14-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-5,7,9,9-tetramethyl-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione;4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-, (1S,3S,7S,10R,11S,12S,16R)-
CBNumber:
CB11311786
Molecular Formula:
C26H39NO7S
Molecular Weight:
509.66
MOL File:
201049-37-8.mol
Modify Date:
2023/7/14 17:47:59
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epothilone E Properties

Boiling point 715.5±60.0 °C(Predicted)
Density 1.187±0.06 g/cm3(Predicted)
pka 13.15±0.10(Predicted)

epothilone E Chemical Properties,Uses,Production

Uses

Epothilone E is a related compound of Epothilones, which are a novel class of antineoplastic agents with antitubulin activity. In addition, Epothilones utilize a similar mechanism of action to that of taxanes and are less susceptible to multidrug resistance caused by P-glycoprotein. Studies showed that Epothilones exhibit antitumor activity against human cancer cells that are taxane-resistant.

epothilone E Preparation Products And Raw materials

Raw materials

Preparation Products

epothilone E Suppliers

Global( 16)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25655 58 Inquiry
cjbscvictory 13348960310 13348960310 China 10011 58 Inquiry
https://hanhongsci.com/ 021-54306202 18917919676 China 29990 58 Inquiry
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 18162595016 China 9131 58 Inquiry
Hubei Weideli Chemical Reagent Co.，Ltd. 027-59222918 13385289472 China 4563 58 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
CarboMer, Inc. 858 552 0992 United States 4027 67 Inquiry
Shanghai Linka Biotechnology Co., Ltd. 15901858719 China 311 55 Inquiry
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 China 56068 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
Dideu Industries Group Limited 58
cjbscvictory 58
https://hanhongsci.com/ 58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd 58
Hubei Weideli Chemical Reagent Co.，Ltd. 58
TargetMol Chemicals Inc. 58
CarboMer, Inc. 67
Shanghai Linka Biotechnology Co., Ltd. 55
Shenzhen Polymeri Biochemical Technology Co., Ltd. 58

201049-37-8(epothilone E)Related Search:

(-)-Huperzine A Ribonucleic acid florfenicol(Water soluble) Florfenicol Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9-tetramethyl-16-(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-, (4S,7R,8S,9S,13Z,16S)-
Epothilone A Epothilone D
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epothilone E [4S,7R,8S,9S,13R,14S,16S(E)]-13,14-Epoxy-4,8-dihydroxy-5,5,7,9-tetramethyl-16-[2-[2-(hydroxymethyl)thiazol-4-yl]-1-methylvinyl]-1-oxacyclohexadecane-2,6-dione (1R,5S,6S,7R,10S,14S,16S)-6,10-dihydroxy-14-[(E)-1-[2-(hydroxymethyl)-1,3-thiazol-4-yl]prop-1-en-2-yl]-5,7,9,9-tetramethyl-13,17-dioxabicyclo[14.1.0]heptadecane-8,12-dione 4,17-Dioxabicyclo[14.1.0]heptadecane-5,9-dione, 7,11-dihydroxy-3-[(1E)-2-[2-(hydroxymethyl)-4-thiazolyl]-1-methylethenyl]-8,8,10,12-tetramethyl-, (1S,3S,7S,10R,11S,12S,16R)- epothilone E USP/EP/BP 201049-37-8