Chinese english Japanese Germany Korea
ChemicalBook > Product Catalog >API >Antibiotics >Other antibiotic Drugs >BORRELIDIN

BORRELIDIN

BORRELIDIN Structure
CAS No.
7184-60-3
Chemical Name:
BORRELIDIN
Synonyms
Aids128115;BORRELIDIN;NSC 216128;Aids-128115;BORRELIDINE;TREPONEMYCIN;Antispirochetin;Quinquangulin K 182;Quinquangulin K 031;BORRELIDIN USP/EP/BP
CBNumber:
CB1134351
Molecular Formula:
C28H43NO6
Molecular Weight:
489.64
MOL File:
7184-60-3.mol
Modify Date:
2025/1/27 9:38:02
Request For Quotation

BORRELIDIN Properties

Melting point 143-145℃
Boiling point 584.45°C (rough estimate)
Density 1.1362 (rough estimate)
refractive index 1.6290 (estimate)
storage temp. −20°C
solubility DMSO: 1 mg/mL
form White to off-white powder.
pka 4.56±0.40(Predicted)
color Off-white
biological source Streptomyces parvulus
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P271-P280
Safety Statements  24/25
WGK Germany  3
RTECS  ED8750000
HS Code  29419090
NFPA 704
0
2 0

BORRELIDIN price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) B3061 Borrelidin from Streptomyces parvulus, ≥98% (HPLC) 7184-60-3 1MG ₹65686.1 2022-06-14 Buy
Product number Packaging Price Buy
B3061 1MG ₹65686.1 Buy

BORRELIDIN Chemical Properties,Uses,Production

Uses

Borrelidin is an unusual nitrile-containing metabolite isolated from Streptomyces. Originally discovered as active against Borrelia species, borrelidin has since found a role as a selective inhibitor of bacterial and eukaryal threonyl-tRNA synthetase. More recent research has found that borrelidin is a very potent angiogenesis inhibitor and induces apoptosis of the capillary tube-forming cells. Borrelidin is an important lead for antimalarial discovery, displaying activity against drug-resistant Plasmodia.

Definition

ChEBI: A macrolide that is isolated from several Streptomyces species and displays antibiotic, antineoplastic and antimalarial properties.

General Description

Chemical structure: macrolide

BORRELIDIN Preparation Products And Raw materials

Raw materials

Cyclopentanecarboxylic acid, 2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11, 13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-, 2-(trimethylsilyl)ethyl ester, (1R,2R)- 1,2-Cyclopentanedicarboxylic acid, 1,2-dimethyl ester, (1R,2R)- 1-Pentanol, 5-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-2,4-dimethyl-, (2S,4R)- (1R,2R)-1,2-Cyclopentanedimethanol 1,2-Cyclopentanedicarboxylic acid, 4-oxo-, 1,2-diMethyl ester, (1R,2R)-

Preparation Products

BORRELIDIN Suppliers

Global( 90)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
BOC Sciences +1-631-485-4226 United States 19552 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29808 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32200 58 Inquiry
Shaanxi Dideu Medichem Co. Ltd +86-029-89586680 +86-18192503167 China 7859 58 Inquiry
TargetMol Chemicals Inc. United States 38636 58 Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd. +86-18621343501; +undefined18621343501 China 33338 58 Inquiry
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd +8618791163155 China 3558 58 Inquiry
SHANGHAI KEAN TECHNOLOGY CO., LTD. +8613817748580 China 40066 58 Inquiry
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 China 9803 58 Inquiry
Supplier Advantage
CLEARSYNTH LABS LTD. 58
BOC Sciences 58
career henan chemical co 58
TargetMol Chemicals Inc. 58
Shaanxi Dideu Medichem Co. Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Acmec Biochemical Technology Co., Ltd. 58
Shaanxi Cuikang Pharmaceutical Technology Co., Ltd 58
SHANGHAI KEAN TECHNOLOGY CO., LTD. 58
Shanghai EFE Biological Technology Co., Ltd. 58

7184-60-3(BORRELIDIN)Related Search:

Bortezomib 17-AAG Alsterpaullone FASCAPLYSIN CHLORIDE Streptozotocin
BORRELIDIN Dodecanenitrile LinoleicAcid 2-(1-Hydroxyethyl)acrylonitrile UNDECANENITRILE
chevron_left

1of2

chevron_right
2-(7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADECA-4,6-DIEN-2-YL)-CYCLOPENTANECARBOXYLIC ACID BORRELIDIN BORRELIDINE 2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)cyclopentane-1-carboxylic acid Aids128115 Aids-128115 Cyclopentanecarboxylic acid, 2-(7-cyano-8, 16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4, 6-dien-2-yl)- Quinquangulin K 031 Quinquangulin K 182 NSC 216128 TREPONEMYCIN TreponeMycin, U 78548, C2989 Borrelidin, froM StreptoMyces sp. NSC 216128 Borrelidin Treponemycin (1R,2R)-2-((2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)cyclopentanecarboxylic acid Borrelidin, 99%, from Streptomyces sp. Cyclopentanecarboxylic acid, 2-[(2S,4E,6Z,8R,9S,11R,13S,15S,16S)-7-cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl]-, (1R,2R)- BORRELIDIN USP/EP/BP Antispirochetin Borrelidin, threonyl-tRNA synthetase inhibitor 7184-60-3 C28H43NO6 Antibiotics Antibiotics A to Z Antibiotics A-F BioChemical