Cedrol
- CAS No.
- 77-53-2
- Chemical Name:
- Cedrol
- Synonyms
- CEDROL CRYSTALS;alpha-Cedrol;(+)-CEDROL;CEDRENOL B;Cedrol crystal;(1S,2R,5S,7R,8R)-2,6,6,8-TETRAMETHYLTRICYCLO[5.3.1.01.5]UNDECAN-8-OL;1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-, (3R,3aS,6R,7R,8aS)-;CEDROL;Cedrol >Cedran-8-ol
- CBNumber:
- CB1165544
- Molecular Formula:
- C15H26O
- Molecular Weight:
- 222.37
- MOL File:
- 77-53-2.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/2 8:55:00
| Melting point | 55-59 °C(lit.) |
|---|---|
| Boiling point | 273 °C(lit.) |
| alpha | D28 +9.9° (c = 5 in chloroform) |
| Density | 0.9479 |
| refractive index | n20/D1.509-1.515 |
| FEMA | 4503 | (+)-CEDROL |
| Flash point | 200 °F |
| storage temp. | 2-8°C |
| solubility | Soluble in DMSO (10 mg/ml) |
| pka | 15.35±0.60(Predicted) |
| form | Solid |
| color | White |
| Odor | at 100.00 %. cedarwood woody dry sweet soft |
| Odor Type | woody |
| optical activity | [α]20/D +10.5±1°, c = 5% in chloroform |
| JECFA Number | 2030 |
| Merck | 14,1911 |
| BRN | 2206347 |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
| LogP | 4.33 |
| CAS DataBase Reference | 77-53-2(CAS DataBase Reference) |
| NIST Chemistry Reference | Cedrol(77-53-2) |
| EPA Substance Registry System | 1H-3a,7-Methanoazulen-6-ol, octahydro-3,6,8,8-tetramethyl-, (3R,3aS,6R,7R,8aS)- (77-53-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | PB7728666 | |||||||||
| HS Code | 29062990 | |||||||||
| Toxicity | LD50 skin in rabbit: > 5gm/kg | |||||||||
| NFPA 704 |
|
Cedrol price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | CRM40903 | (+)-Cedrol solution certified reference material, 2000?μg/mL in methanol, ampule of 1?mL | 77-53-2 | 1ML | ₹9323.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 22135 | (+)-Cedrol ≥99.0% (sum of enantiomers, GC) | 77-53-2 | 5G | ₹13098.25 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C2854 | Cedrol min. 98.0 % | 77-53-2 | 5G | ₹6400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C2854 | Cedrol min. 98.0 % | 77-53-2 | 25G | ₹14800 | 2022-05-26 | Buy |
Cedrol Chemical Properties,Uses,Production
Chemical Properties
Colorless crystals; cedarwood odor. soluble in 11 parts of 95% alcohol. Combustible.
Occurrence
Found in the wood of several conifers, particularly cypresses and cedars, including Cedrus atlantica, Cupressus sempervirens, Juniperus virginiana (Fenarolfs Handbook of Flavor Ingredients, 1971).
Uses
(+)-Cedrol can be used as a starting material for the preparation of cedryl acetate by acetylation using acetic anhydride in the presence of an acid catalyst. It can also be incorporated as a precursor for the total synthesis of rare illicium sesquiterpene (+)-pseudoanisatin via selective C-H bond functionalization.
Preparation
From cedarwood by fractional distillation followed by recrystallization from suitable solvents of appropriate solid fractions.
Definition
A tertiary terpene alcohol.
General Description
(+)-Cedrol is a crystalline hydrated product of α-cedrene, which is a sesquiterpene found in cedar-wood oil. It can be used as a fragrance ingredient in cosmetics, shampoos, and soaps as well as in non-cosmetic products such as cleaners and detergents. (±) Cedrol can be synthesized by intramolecular Diels-Alder reaction of alkyl cyclopentadiene.
Purification Methods
Purify cedrol by recrystallisation from aqueous MeOH. It is estimated colorimetrically with H3PO4 in EtOH followed by vanillin and HCl [Hayward & Seymour Anal Chem 20 572 1948]. The 3,5-dinitrobenzoyl derivative has m 92-93o. [Stork & Clarke J Am Chem Soc 83 3114 1961, Beilstein 6 III 424.]
Cedrol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| HRV Global Life Sciences | +91-9820219686 +91-9820219686 | Telangana, India | 379 | 58 | Inquiry |
| Aamirav Ingredients And Specialties Pvt Ltd | +91-2224980102 +91-9820077171 | Maharashtra, India | 138 | 58 | Inquiry |
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| Arpan Aromatics | 08048372666Ext 828 | Ahmedabad, India | 138 | 58 | Inquiry |
| HRV Global Life Sciences Private Limited | 91-40-23554991 | Hyderabad, India | 190 | 58 | Inquiry |
| Akshaya Laboratories Pvt. Ltd | -64642624 | Hyderabad, India | 125 | 58 | Inquiry |
| Karnataka Aromas | 08068970631Ext 815 | Karnataka, India | 104 | 58 | Inquiry |
| Phytocompounds | 91-80-40209999 | Karnataka, India | 35 | 58 | Inquiry |
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