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Sodium bis(trimethylsilyl)amide

CAS No.: 1070-89-9

Chemical Name:: Sodium bis(trimethylsilyl)amide

Synonyms: NAHMDS;SODIUM HEXAMETHYLDISILAZANE;SODIUM HEXAMETHYLDISILAZIDE;Sodium Bis(trimethylsilyl)amide, 1M THF;HMDS Na;N-SODIOHEXAMETHYLDISILAZANE;Sodiobis(trimethylsilyl)amine;sodium bis(trimethylsilyl)amide solution;HMN NA SALT;sodiumbis(tri

CBNumber:: CB8382263

Molecular Formula:: C6H18NNaSi2

Molecular Weight:: 183.37

MOL File:: 1070-89-9.mol

MSDS File:: SDS

Modify Date:: 2024/7/29 15:17:36

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Sodium bis(trimethylsilyl)amide Properties

Melting point	171-175 °C (lit.)
Boiling point	67°C
Density	0.904 g/mL at 25 °C
Flash point	43 °F
storage temp.	2-8°C
solubility	Soluble in hexane, toluene, ether,terahydrofuran, benzene and toluene.
form	Liquid
Specific Gravity	0.9
color	Clear orange to brown
Water Solubility	reacts
Hydrolytic Sensitivity	8: reacts rapidly with moisture, water, protic solvents
Sensitive	Moisture Sensitive
BRN	3629917
Exposure limits	ACGIH: TWA 50 ppm; STEL 100 ppm (Skin) OSHA: TWA 200 ppm(590 mg/m3) NIOSH: IDLH 2000 ppm; TWA 200 ppm(590 mg/m3); STEL 250 ppm(735 mg/m3)
CAS DataBase Reference	1070-89-9(CAS DataBase Reference)
EPA Substance Registry System	Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, sodium salt (1070-89-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363

Hazard Codes

C,F

Risk Statements

14-34-19-11-67-65-63-48/20-14/15-40-37

Safety Statements

26-45-62-36/37/39-33-16-43-8

RIDADR

UN 3263 8/PG 2

WGK Germany

10-21

TSCA

Yes

HazardClass

4.3

PackingGroup

III

HS Code

29319090

NFPA 704

	3
3		2
	W

Sodium bis(trimethylsilyl)amide price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	80631	Sodium bis(trimethylsilyl)amide solution 40% in THF	1070-89-9	500ML	₹12355.7	2022-06-14	Buy
Sigma-Aldrich(India)	245585	Sodium bis(trimethylsilyl)amide solution 1.0?M in THF	1070-89-9	100ML	₹2874.9	2022-06-14	Buy
Sigma-Aldrich(India)	368059	Sodium bis(trimethylsilyl)amide solution 0.6?M in toluene	1070-89-9	100ML	₹6251	2022-06-14	Buy
Sigma-Aldrich(India)	771546	Sodium bis(trimethylsilyl)amide solution 0.5?M in methyl tert-butyl ether	1070-89-9	100ML	₹6490.4	2022-06-14	Buy
Sigma-Aldrich(India)	245585	Sodium bis(trimethylsilyl)amide solution 1.0?M in THF	1070-89-9	4X25ML	₹12103	2022-06-14	Buy

Product number	Packaging	Price	Buy
80631	500ML	₹12355.7	Buy
245585	100ML	₹2874.9	Buy
368059	100ML	₹6251	Buy
771546	100ML	₹6490.4	Buy
245585	4X25ML	₹12103	Buy

Sodium bis(trimethylsilyl)amide Chemical Properties,Uses,Production

Chemical Properties

Slightly yellow to light beige crystalline powder

Physical properties

mp 171–175 °C; bp 170 °C/2 mmHg.

Uses

Sodium bis(trimethylsilyl)amide is a synthetically useful reagent in that it combines both high basicity and nucleophilicity, each of which may be exploited for useful organic transformations such as selective formation of enolates, preparation of Wittig reagents, formation of acyl anion equivalents, and the generation of carbenoid species. As a nucleophile, it has been used as a nitrogen source for the preparation of primary amines.It is useful as a sterically hindered base and as a nucleophile.

General Description

Sodium bis(trimethylsilyl)amide solution (NaHMDS) is widely used as a strong base in organic synthesis for deprotonation reactions and base-catalyzed reactions. It is also involved in the generation of enolates, Wittig reagents and carbenes.

Purification Methods

It can be sublimed at 170o/2mm (bath temperature 220-250o) onto a cold finger, and can be recrystallised from *C6H6 (its solubility is: 10g in 100mL at 60o). It is slightly soluble in Et2O and is decomposed by H2O. [Wannagat & Niederprüm Chem Ber 94 1540 1961.]It is available commercially under N2 in Sure/Seal bottles in tetrahydrofuran (various concentrations) and at ~0.6M in toluene. [Beilstein 4 IV 4014.]

Sodium bis(trimethylsilyl)amide Preparation Products And Raw materials

Raw materials

Toluene Sodium Tetrahydrofuran Hexamethyldisilazane

Preparation Products

TERT-BUTYL 4-FORMYLPYRIDIN-3-YLCARBAMATE NONAMETHYLTRISILAZANE TRIS[N,N-BIS(TRIMETHYLSILYL)AMIDE]CERIUM(III)

Sodium bis(trimethylsilyl)amide Suppliers

Global( 400)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
GLR Innovations	+91 9891111994	New Delhi, India	4542	58	Inquiry
SURVIVAL TECHNOLOGIES LIMITED	+91 8108285261	Gujarat, India	294	58	Inquiry
VASISTA LIFE SCIENCES PRIVATE LIMITED	+91-04029554774 +91-9010855544	Hyderabad, India	153	58	Inquiry
Oceanic Pharmachem Pvt Ltd	+91-91-2242128600 +91-2242128600	Maharashtra, India	33	58	Inquiry
JLS Laboratories Pvt Limited	+91 8790545679	Hyderabad, India	62	58	Inquiry
AMINO ORGANICS	+919866989891	Hyderabad, India	275	58	Inquiry
JSK Chemicals	+919879767970	Gujarat, India	3756	58	Inquiry
BASF India Limited	+91-2262785600 +91-2262785600	Maharashtra, India	209	58	Inquiry
Organo Metallics	+91-9391016448 +91-9705345345	Telangana, India	32	58	Inquiry
Suparna Chemicals Ltd	+91-2222027446 +91-9820623254	Maharashtra, India	19	58	Inquiry

Supplier	Advantage
GLR Innovations	58
SURVIVAL TECHNOLOGIES LIMITED	58
VASISTA LIFE SCIENCES PRIVATE LIMITED	58
Oceanic Pharmachem Pvt Ltd	58
JLS Laboratories Pvt Limited	58
AMINO ORGANICS	58
JSK Chemicals	58
BASF India Limited	58
Organo Metallics	58
Suparna Chemicals Ltd	58

Sodium bis(trimethylsilyl)amide Spectrum

Sodium bis(trimethylsilyl)amide(1070-89-9)IR1 Sodium bis(trimethylsilyl)amide(1070-89-9)IR2 Sodium bis(trimethylsilyl)amide(1070-89-9)Raman

1070-89-9(Sodium bis(trimethylsilyl)amide)Related Search:

Release agent No.8 Methanesiliconic acid sodium salt Sodium amide Hexamethyldisilazane Fomesafen

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Rink Amide Linker Sodium benzoate Sodium acetate Sodium bicarbonate Hexamethyldisiloxane

Bis(triphenylphosphinepalladium) acetate Potassium bis(trimethylsilyl)amide Bis(triphenylphosphine)nickel(II)chloride

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