ChemicalBook > Product Catalog >Chemical Reagents >Organic reagents >Silane >N-(Trimethylsilyl)acetamide
N-(Trimethylsilyl)acetamide
- CAS No.
- 13435-12-6
- Chemical Name:
- N-(Trimethylsilyl)acetamide
- Synonyms
- TMSA;DK063;TMS ACETAMIDE;trimethylsilyl;N-TMS-acetamide;N-(Trimethylsilyl);TRIMETHYLSILYLACETAMIDE;N-TRIMETHYLSILYLACETAMIDE;n-(trimethylsilyl)-acetamid;(acetylamino)trimethylsilane
- CBNumber:
- CB7667530
- Molecular Formula:
- C5H13NOSi
- Molecular Weight:
- 131.25
- MOL File:
- 13435-12-6.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/4/26 17:21:34
| Melting point | 46-49 °C(lit.) |
|---|---|
| Boiling point | 84 °C18 mm Hg(lit.) |
| Density | 0.859±0.06 g/cm3(Predicted) |
| Flash point | 135 °F |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform, DMSO, Methanol |
| pka | 18.23±0.46(Predicted) |
| form | Crystalline Mass |
| color | White to yellow |
| Water Solubility | reacts |
| Sensitive | Moisture Sensitive |
| Hydrolytic Sensitivity | 7: reacts slowly with moisture/water |
| BRN | 741928 |
| Stability | Moisture Sensitive |
| CAS DataBase Reference | 13435-12-6(CAS DataBase Reference) |
| EPA Substance Registry System | Acetamide, N-(trimethylsilyl)- (13435-12-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi-F,Xi,F | |||||||||
| Risk Statements | 36/37/38-11 | |||||||||
| Safety Statements | 37/39-26 | |||||||||
| RIDADR | 1325 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | AD0250000 | |||||||||
| F | 10-21 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 4.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29319090 | |||||||||
| NFPA 704 |
|
N-(Trimethylsilyl)acetamide price More Price(2)
N-(Trimethylsilyl)acetamide Chemical Properties,Uses,Production
Chemical Properties
WHITE TO YELLOWISH CRYSTALLINE MASS
Uses
N-Trimethylsilylacetamide is a silylating agent used in organic synthesis. N-Trimethylsilylacetamide is used in the preparation of the antibacterial agent Cefdinir (C242670).
General Description
The efficiency of N-(Trimethylsilyl)acetamide (TMS acetamide) as allyl group scavenger and its compatibility with Fluorenylmethyloxycarbonyl chloride (Fmoc) protecting groups were studied.
Purification Methods
Distil the amide repeatedly in an inert atmosphere with all operations to be performed in an anhydrous atmosphere. In the presence of moisture, trimethylsilanol (b 31-34o/26mm) is formed and is a likely impurity (check by NMR). [Birkofer et al. Chem Ber 96 1473 1963, Beilstein 4 IV 4011.]
N-(Trimethylsilyl)acetamide Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 181)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| HiMedia Laboratories | 91-22-61471919 | Maharashtra, India | 1843 | 58 | Inquiry |
| Hubei Changfu Chemical Co., Ltd. | +86-027-84396550 +8617721064038 | China | 411 | 58 | Inquiry |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | China | 16209 | 58 | Inquiry |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21675 | 55 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32760 | 60 | Inquiry |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49391 | 58 | Inquiry |
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N-(TRIMETHYLSILYL)ACETAMIDE FOR SYNTHESI
N-(Trimethylsilyl)acetamide,97%
N-(Trimethylsilyl)
(acetylamino)trimethylsilane
n-(trimethylsilyl)-acetamid
N-TRIMETHYLSILYLACETAMIDE
TRIMETHYLSILYLACETAMIDE
TMSA
TMS ACETAMIDE
N-TrimethylsilylacetamideA.R.
trimethylsilyl
N-TRIMETHYLSILYL ACETAMIDE(TMSA)
N-TMS-acetamide
Acetamide, N-(trimethylsilyl)-
N-Trimethylsilylacetamide >
13435-12-6 N-(Trimethylsilyl)acetamide
DK063
13435-12-6
C5H13NOSi
CH3CONHSiCH33
Derivatization Reagents
Fluka Reagents
Organic Building Blocks
Si (Classes of Silicon Compounds)
Silylation (GC Derivatizing Reagents)
Silylacetamides
Acyclic
Alkenes
Analytical Chromatography Product Catalog
Building Blocks
Trimethylsilylation (GC Derivatizing Reagents)
Si-N Compounds
GC Derivatizing Reagents
Silicon Compounds (for Synthesis)
Aliphatics
Miscellaneous Reagents
Analytical Chemistry
GC Derivatizing Reagents
Si (Classes of Silicon Compounds)
Silicon Compounds (for Synthesis)
Silylacetamides
Silylation (GC Derivatizing Reagents)
Si-N Compounds
Synthetic Organic Chemistry
Trimethylsilylation (GC Derivatizing Reagents)