Cefdinir
![Cefdinir Structure](CAS/GIF/91832-40-5.gif)
- CAS No.
- 91832-40-5
- Chemical Name:
- Cefdinir
- Synonyms
- Omnicef;Cefzon;CFDN;Omnice;FK-482;CI 983;Novacef;CEFDINIR;cefdinyl;bmy28488
- CBNumber:
- CB7483101
- Molecular Formula:
- C14H13N5O5S2
- Molecular Weight:
- 395.41
- MOL File:
- 91832-40-5.mol
- Modify Date:
- 2024/8/5 12:01:54
Melting point | >180°C dec. |
---|---|
Density | 1.89±0.1 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
solubility | dilute HCl: slightly soluble |
pka | 9.70(at 25℃) |
form | solid |
color | Pale Yellow to Light Yellow |
Water Solubility | Soluble in water |
λmax | 295nm(DMSO)(lit.) |
Merck | 14,1920 |
BCS Class | 4 |
InChIKey | RTXOFQZKPXMALH-GHXIOONMSA-N |
SMILES | N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\O)=O)C1=O)SCC(C=C)=C2C(O)=O |
CAS DataBase Reference | 91832-40-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS08 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Danger | |||||||||
Hazard statements | H317-H334 | |||||||||
Precautionary statements | P261-P272-P280-P284-P302+P352+P333+P313+P363-P304+P340+P342+P311-P501 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | XI0367250 | |||||||||
HS Code | 2941906000 | |||||||||
Toxicity | LD50 orl-rat: >5600 mg/kg IYKEDH 23,93,1992 | |||||||||
NFPA 704 |
|
Cefdinir price More Price(3)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | C7118 | Cefdinir ≥97.0% (HPLC) | 91832-40-5 | 1G | ₹10413.65 | 2022-06-14 | Buy |
TCI Chemicals (India) | C3111 | Cefdinir | 91832-40-5 | 1G | ₹7600 | 2022-05-26 | Buy |
TCI Chemicals (India) | C3111 | Cefdinir | 91832-40-5 | 5G | ₹14800 | 2022-05-26 | Buy |
Cefdinir Chemical Properties,Uses,Production
Description
Cefdinir is an orally active, beta-lactamase stable cephalosporin with a broad spectrum of activity. Compared to other oral cephalosporins, cefdinir is more potent against Gram-positive bacteria, especially Staphylococci. Its activity against Gram-negative bacteria such as E.coli,K. pneumoniae and P.mirabilis is similar to cefixime, but superior to cefaclor and cephalexin.
Chemical Properties
Pale Yellow Solid
Uses
A Cephalosporin antibiotic structurally similar to Cefixime
Definition
ChEBI: A cephalosporin compound having 7beta-2-(2-amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino- and 3-vinyl side groups.
Antimicrobial activity
An oral cephalosporin similar in structure to cefixime, but
with a slightly modified side chain at the 7-amino position.
Activity is similar to that of cefixime, but it is more active,
especially against staphylococci. It is not hydrolyzed
by staphylococcal or the common plasmid-mediated
enterobacterial β-lactamases. An enhancing effect on phagocytosis
has been demonstrated in vitro.
Oral absorption is about 35%. A 200 mg oral dose achieves
a plasma concentration of 1 mg/L after c. 3 h. Absorption is
reduced after a fatty meal. Concentrations equal to or higher
than corresponding plasma levels were present in blister fluid
6–12 h after administration of an oral dose. The plasma halflife
is 1.5 h. Protein binding is 60–70%. A total of 12–20%
of the dose was excreted in the urine within 12 h, the renal
elimination declining with increasing dose. The elimination
half-life and peak plasma concentration are increased in renal
failure. About 60% of the drug is removed by hemodialysis.
Side effects and uses are those common to oral
cephalosporins.
Safety Profile
Moderately toxic by ingestion andintravenous routes. Low toxicity by intraperitoneal andsubcutaneous routes. Experimental reproductive effects.When heated to decomposition it emits toxic vapors ofNOx and SOx.
Cefdinir Preparation Products And Raw materials
Raw materials
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chevron_rightPreparation Products
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Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
Aurobindo Pharma Limited | +914066725000 | Telangana, India | 112 | 58 | Inquiry |
Ralington Pharma | +91-7948911722 +91-9687771722 | Gujarat, India | 1350 | 58 | Inquiry |
Covalent Laboratories Private Limited (Virchow Group) | +91-4049483333 +91-9866077161 | Telangana, India | 9 | 58 | Inquiry |
Suvan LifeSciences (formerly Sansh Biotech Pvt Ltd) | +91-1142631798 +91-9899000024 | New Delhi, India | 55 | 58 | Inquiry |
Akums Lifesciences Ltd | +91-1147511000 +91-1147511000 | New Delhi, India | 38 | 58 | Inquiry |
OCEAN TRADING CORPORATION | +91(22) 24921669 | New Delhi, India | 6211 | 58 | Inquiry |
SL Drugs and Pharmaceuticals Pvt. Ltd. | +91 (40) 6661-1133 | New Delhi, India | 2688 | 50 | Inquiry |
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