Cefdinir
|
|
Cefdinir 속성
- 녹는점
- >180°C dec.
- 밀도
- 1.89±0.1 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Sealed in dry,2-8°C
- 용해도
- 묽은 HCl: 약간 용해됨
- 산도 계수 (pKa)
- 9.70(at 25℃)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 연한 노란색에서 밝은 노란색까지
- 수용성
- 물에 용해됨
- 최대 파장(λmax)
- 295nm(DMSO)(lit.)
- Merck
- 14,1920
- BCS Class
- 4
- InChIKey
- RTXOFQZKPXMALH-GHXIOONMSA-N
- SMILES
- N12[C@@]([H])([C@H](NC(/C(/C3=CSC(N)=N3)=N\O)=O)C1=O)SCC(C=C)=C2C(O)=O
- CAS 데이터베이스
- 91832-40-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 | ||
---|---|---|---|
RTECS 번호 | XI0367250 | ||
HS 번호 | 2941906000 | ||
독성 | LD50 orl-rat: >5600 mg/kg IYKEDH 23,93,1992 |
Cefdinir C화학적 특성, 용도, 생산
개요
Cefdinir is an orally active, beta-lactamase stable cephalosporin with a broad spectrum of activity. Compared to other oral cephalosporins, cefdinir is more potent against Gram-positive bacteria, especially Staphylococci. Its activity against Gram-negative bacteria such as E.coli,K. pneumoniae and P.mirabilis is similar to cefixime, but superior to cefaclor and cephalexin.화학적 성질
Pale Yellow Solid용도
A Cephalosporin antibiotic structurally similar to Cefixime정의
ChEBI: A cephalosporin compound having 7beta-2-(2-amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino- and 3-vinyl side groups.Antimicrobial activity
An oral cephalosporin similar in structure to cefixime, but with a slightly modified side chain at the 7-amino position. Activity is similar to that of cefixime, but it is more active, especially against staphylococci. It is not hydrolyzed by staphylococcal or the common plasmid-mediated enterobacterial β-lactamases. An enhancing effect on phagocytosis has been demonstrated in vitro.Oral absorption is about 35%. A 200 mg oral dose achieves a plasma concentration of 1 mg/L after c. 3 h. Absorption is reduced after a fatty meal. Concentrations equal to or higher than corresponding plasma levels were present in blister fluid 6–12 h after administration of an oral dose. The plasma halflife is 1.5 h. Protein binding is 60–70%. A total of 12–20% of the dose was excreted in the urine within 12 h, the renal elimination declining with increasing dose. The elimination half-life and peak plasma concentration are increased in renal failure. About 60% of the drug is removed by hemodialysis.
Side effects and uses are those common to oral cephalosporins.
Safety Profile
Moderately toxic by ingestion andintravenous routes. Low toxicity by intraperitoneal andsubcutaneous routes. Experimental reproductive effects.When heated to decomposition it emits toxic vapors ofNOx and SOx.Cefdinir 준비 용품 및 원자재
원자재
Amine compound
아세틸브로마이드
아니졸
트리플루오로아세트 산
(트리페닐포스포라닐리덴)아세트알데히드
초산에틸
N-(Trimethylsilyl)acetamide
N,N-디메틸아세트아미드
염화메틸
아질산 나트륨
S-2-BENZOTHIAZOLYL (Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO THIOACETATE
(Benzothiazol-2-yl)-(Z)-2-trityloxyimino-2-(2-aminothiazole-4-yl)-thioacetate
7-AVCA
준비 용품
Cefdinir 공급 업체
글로벌( 474)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Shenzhen Excellent Biomedical Technology Co.,Ltd. | +86-0755-26050679 +86-15915472436 |
sale@ex-biotech.cn | China | 1031 | 58 |
Hebei Jingbo New Material Technology Co., Ltd | +8619931165850 |
hbjbtech@163.com | China | 1000 | 58 |
Hebei Saisier Technology Co., LTD | +86-18400010335 +86-18034520335 |
admin@hbsaisier.cn | China | 996 | 58 |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 |
sarah@tnjone.com | China | 1143 | 58 |
Hebei Longbang Technology Co., LTD | +86-18032476855 +86-18032476855 |
admin@hblongbang.com | China | 935 | 58 |
HebeiShuoshengImportandExportco.,Ltd | +86-18532138899 +86-18532138899 |
L18532138899@163.com | China | 931 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21668 | 55 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29894 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Cefdinir 관련 검색:
트리에톡시비닐실란 베타인 글리신 2-피로리딘온,1-에테닐- 비닐 프로피온산염 에틸렌 산소, 냉각된 액체
4-(4-CHLORO-BENZYLOXY)-PHENYLAMINE
ALTRENOGEST
CHLOROPHOSPHONAZO III
Vinyl ester resin
Silicone rubber,methyl-vinyl
Vinyl resin
Cefixime
Ceftiolene
Cefditoren
Cefditoren pivoxil
(Z)-2-(5-AMINO-1,2,4-THIADIAZOL-3-YL)-2-METHOXYIMINO ACETIC ACID