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ChemicalBook > Product Catalog >Biochemical Engineering >Amino Acids and Derivatives >Other Amino Acid Protection >Rink Amide Linker

Rink Amide Linker

Rink Amide Linker Structure
CAS No.
145069-56-3
Chemical Name:
Rink Amide Linker
Synonyms
FMoc-Linker;RINK AMIDE LINKER;FMOC-RINK LINKER;DK7874;RAMAGE;Fmoc-Liner;KNORR LINKER;Rink Amide Linke;Rink AMind Linker;FMOC-AMIDE-LINKER
CBNumber:
CB3104341
Molecular Formula:
C32H29NO7
Molecular Weight:
539.58
MOL File:
145069-56-3.mol
MSDS File:
SDS
Modify Date:
2023/11/16 17:07:08
Request For Quotation

Rink Amide Linker Properties

Melting point ~180 °C (dec.)
storage temp. 2-8°C
solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
BRN 5841553
InChIKey UPMGJEMWPQOACJ-UHFFFAOYSA-N
SMILES C(O)(=O)COC1=CC=C(C(C2=CC=C(OC)C=C2OC)NC(OCC2C3C(=CC=CC=3)C3C2=CC=CC=3)=O)C=C1
CAS DataBase Reference 145069-56-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  22-24/25-37/39-26
WGK Germany  3
HS Code  29242995

Rink Amide Linker price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 38784 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid ≥99.0% (HPLC) 145069-56-3 5G ₹23089.73 2022-06-14 Buy
SRL 23311 Rink Amide Linker Resin (Knorr Linker) extrapure, 99% 145069-56-3 1Gms ₹5250 2022-05-26 Buy
SRL 23311 Rink Amide Linker Resin (Knorr Linker) extrapure, 99% 145069-56-3 5Gms ₹9450 2022-05-26 Buy
Product number Packaging Price Buy
38784 5G ₹23089.73 Buy
23311 1Gms ₹5250 Buy
23311 5Gms ₹9450 Buy

Rink Amide Linker Chemical Properties,Uses,Production

Uses

Rink amide linker (CAS# 145069-56-3) is a selective aldose reductase inhibitor and a potential antidiabetic drug.

Application

Most linkers are bifunctional spacers, with one end permanently anchoring to the resin and the other end temporarily linking to the peptide. Peptides anchoring to Rink linker can be easily cleaved under acidic conditions. Since the discovery of Rink linker, it has been grafted to a variety of resins and widely used for scientific investigations and industrial solid-phase peptide synthesis. Thus, Rink Amide Linker is the key reagent to prepare this series of Rink-resins[1].

Origin

Rink Amide Linker was first designed by Rink and further developed by Bernatowicz and co-workers for the preparation of peptide C-terminal amides[1]. Rink Amide Linker is also known as commercial Knorr linker.

References

[1] Qin L, et al. An improved and practical synthesis of Fmoc Rink linker. Journal of Chemical Research, 2019.

Rink Amide Linker Preparation Products And Raw materials

Raw materials

Preparation Products

Rink Amide Linker Suppliers

Global( 241)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ACE BIOSCIENCES +91-9395105396 +91-9395105396 Telangana, India 81 58 Inquiry
CJEX Biochem Pvt Ltd +91-2222033022 +91-2222033022 Maharashtra, India 17 58 Inquiry
Bharavi Laboratories (P) Ltd. 91 80 2666 7742 New Delhi, India 359 54 Inquiry
Triveni chemicals 08048762458 New Delhi, India 6093 58 Inquiry
Sisco Research Laboratories Pvt. Ltd. +91-22-4268 5800 Mumbai, India 4317 58 Inquiry
Chemtour Biotech Co., Ltd +8617327281506 China 1460 58 Inquiry
SIMAGCHEM CORP +86-13806087780 China 17367 58 Inquiry
Sichuan HongRi Pharma-Tech Co.,Ltd +86-028-64841719 +8617390183901 China 1106 58 Inquiry
Hebei Dangtong Import and export Co LTD 0086 15632927689 +8615632927689 China 983 58 Inquiry
Capot Chemical Co.,Ltd. 571-85586718 +8613336195806 China 29798 60 Inquiry
Supplier Advantage
ACE BIOSCIENCES 58
CJEX Biochem Pvt Ltd 58
Bharavi Laboratories (P) Ltd. 54
Triveni chemicals 58
Sisco Research Laboratories Pvt. Ltd. 58
Chemtour Biotech Co., Ltd 58
SIMAGCHEM CORP 58
Sichuan HongRi Pharma-Tech Co.,Ltd 58
Hebei Dangtong Import and export Co LTD 58
Capot Chemical Co.,Ltd. 60

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Rink AMid Linker, (FoMc-AM, Knorr linker) Rink AMind Linker FMOC-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE 4-[(2,4-DiMethoxyphenyl)(FMoc-aMino)Methyl]phenoxyacetic acid, 98+% RINK AMIDE REAGENT N-FMOC-(2,4-DIMETHOXYPHENYL)AMINOMETHYL PHENOXY ACETIC ACID P-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID P-((R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID P-((R,S)-ALPHA-[1-(9H-FLOUREN-9-YL)-METHOXYFORMAMIDO]-2,4-DIMETHOXYBENZYL)-PHENOXYACETIC ACID N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-2,4-DIMETHOXY-4'-(CARBOXYMETHYLOXY)-BENZHYDRYLAMINE 4-(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC-ACID 4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOXYACETIC ACID 4'-[(R,S)-ALPHA-[1-(9-FLUORENYL)METHOXYCARBONYLAMINO]-2,4-DIMETHOXYBENZYL]-PHENOL 4-[(R,S)-ALPHA-1-(9H-FLUREN-9-YL)-METHOXY FORMAMIDO]-2,4-DIMETHOXYBENZYLPHENOXYACETIC ACID 4-[(R,S)-ALPHA-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID 4-(2',4'-DIMETHOXYPHENYL)-FMOC-AMINOMETHYL-PHENOXYACETIC ACID 4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID FMOC-AMIDE-LINKER FMOC-RINK AMIDE-LINKER FMOC RINK ACETIC ACID LINKER FMOC-NH-SAL RESIN LINKER KNORR LINKER Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(Fmoc Amino)Methyl)Phenoxyacetic Acid 145069-56-3 C32h29no7 Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(Fmoc Amino)Methyl)Phenoxyacetic Acid Fmoc-Liner Fmoc-Linker(4-[(2,4-Dimethoxyphenyl)(Fmoc-Amino)Methyl]-PhenoxyaceticAcid) 4-[(2,4-dimethoxyphenyl)(fmoc-amino)me] phenoxy acetic acid 4-[(2,4-DIMETHOXYPHENYL)(FMOC-AMINO)METHYL]PHENOXYACETIC ACID[RINK AMIDE LINKER] 4-[(2,4-DIMETHOXYPHENYL) (FMOC-AMINO) METHYL] PHENOXYACETIC ACID RINK AMIDE LINKER 98.5% RINK AMIDE LINKER:KNORR LINKER:4-[(R,S)-A-[1-(9H-FLUOREN-9-YL)-METHOXY-FORMAMIDO]-2,4-DIMETHOXYBENZYL-PHENOXYACETIC ACID Knorr-Linker, 4-{(R,S)-alpha-[1-(9-Fluorenyl)methoxycarbonylamino]-2,4-dimethoxybenzyl}-phenoxyacetic acid RINK AMIDE LINKER, 98.5% MIN. 4-[(R,S)--[1-(9H-Fluoren-9-yl)-methoxyformamido]-2,4-dimethoxybenzylphenoxyacetic acid 4-[(R,S)-a-[1-(9H-Fluoren-9-yl)-methoxy-formamido]-2 2-(4-((((9H-fluoren-9-yl)methoxy)carbonylamino)(2,4-dimethoxyphenyl)methyl)phenoxy)acetic acid 4-[(R,S)-a-[1-(9H-Fluoren-9-yl)-methoxy-formamido] 2-{4-[(2,4-diMethoxyphenyl)({[(9H-fluoren-9-ylMethoxy)carbonyl]aMino})Methyl]phenoxy}acetic acid Fmoc-Knorr-Linker: Fmoc-Rink Amide Linker (2), 4′-{(R,S)-alpha-[1-(9-Fluorenyl)methoxycarbonylamino]-2,4-dimethoxybenzyl}-phenoxyacetic acid Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(FMOC amino)methyl)ph Rink Amide Linke 2-[4-[(2,4-dimethoxyphenyl)-[[9H-fluoren-9-ylmethoxy(oxo)methyl]amino]methyl]phenoxy]acetic acid Rink Amide Linker, 99% min. 4-[(2,4-Dimethoxyphenyl)(Fmoc-Amino)Methyl]PhenoxyaceticAci 4-[(2,4-Dimethoxyphenyl)(Fmoc-amino)methyl]phenoxyacetic acid USP/EP/BP DK7874 Rink Amide Linker Resin (Knorr Linker) extrapure, 99% RINK AMIDE LINKER FMOC-RINK LINKER FMoc-Linker RAMAGE 145069-56-3 145068-56-3 C32H28NO7 C32H29NO7 Bifunctional Crosslinkers Linkers Peptide Synthesis Specialty Synthesis