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Bezafibrate

Bezafibrate Structure
CAS No.
41859-67-0
Chemical Name:
Bezafibrate
Synonyms
CEDUR;bf-759;bm15075;Befizal;Bezatol;BEZALIP;Benzabet;Difaterol;Bezabrate;bezafibrat
CBNumber:
CB1188501
Molecular Formula:
C19H20ClNO4
Molecular Weight:
361.82
MOL File:
41859-67-0.mol
MSDS File:
SDS
Modify Date:
2024/11/1 18:09:03

Bezafibrate Properties

Melting point 184 °C
Boiling point 572.1±45.0 °C(Predicted)
Density 1.260±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMF: soluble
form solid
pka 3.29±0.10(Predicted)
color White to Off-White
Merck 14,1195
Stability Hygroscopic
LogP 2.504 (est)
CAS DataBase Reference 41859-67-0(CAS DataBase Reference)
EPA Substance Registry System Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl- (41859-67-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P301+P312+P330
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  1
RTECS  UE8755000
HS Code  29242990
Toxicity LD50 oral in rat: 1082mg/kg
NFPA 704
0
1 0

Bezafibrate price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) B7273 Bezafibrate ≥98%, solid 41859-67-0 1G ₹4135.15 2022-06-14 Buy
Sigma-Aldrich(India) B7273 Bezafibrate ≥98%, solid 41859-67-0 5G ₹13455.48 2022-06-14 Buy
Sigma-Aldrich(India) B7273 Bezafibrate ≥98%, solid 41859-67-0 25G ₹44761.38 2022-06-14 Buy
Sigma-Aldrich(India) 72516 Bezafibrate analytical standard 41859-67-0 500MG ₹6852.23 2022-06-14 Buy
TCI Chemicals (India) B3346 Bezafibrate 41859-67-0 5G ₹5500 2022-05-26 Buy
Product number Packaging Price Buy
B7273 1G ₹4135.15 Buy
B7273 5G ₹13455.48 Buy
B7273 25G ₹44761.38 Buy
72516 500MG ₹6852.23 Buy
B3346 5G ₹5500 Buy

Bezafibrate Chemical Properties,Uses,Production

Description

Bezafibrate is a non-selective agonist of peroxisome proliferator-activated receptors (PPARs; EC50s = 50, 60, and 20 μM for human PPARα, PPARγ, and PPARδ, respectively). It reduces triglyceride levels and the size of lipid droplets in an oleic acid-induced HepaRG hepatocyte model of steatosis when used at a concentration of 25 μM. Bezafibrate (10 mg/kg per day) reduces plasma VLDL and LDL mass and triglyceride and free fatty acid levels in a high-fructose plus lard diet-induced rat model of insulin resistance.

Chemical Properties

Off-White Solid

Uses

Bezafibrate has been used:

  • a supplement in the standard diet (SD)?for mice to study its effect on diabetes
  • to evaluate its effect on hepatitis C virus (HCV) assembly and secretion
  • to evaluate its effect on gonadal steroidogenesis and?spermatogenesis?of zebrafish and also used as standard for HPLC

Bezafibrate Preparation Products And Raw materials

Global( 390)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6202 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6257 58 Inquiry
A.J Chemicals 91-9810153283 New Delhi, India 6100 58 Inquiry
TCI Chemicals (India) Pvt. Ltd. 1800 425 7889 New Delhi, India 6768 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6514 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Taj Mahal Vision Chemicals Private Limited 07942557933 Mumbai, India 206 58 Inquiry
Esschem (Private) Limited 09833911146 Mumbai, India 39 58 Inquiry
BLACK ROSE Industries Ltd +91 43337200 22873022 Mumbai, India 28 58 Inquiry
SPB Pharma Chiemimpex 91-9043046289 Tamil Nadu, India 94 58 Inquiry

Bezafibrate Spectrum

Bezafibrate D6 (dimethyl D6) Bezabrate D6 (DiMethyl D6) 2-(4-{2-[(4-chlorophenyl)forMaMido]ethyl}phenoxy)-2-Methylpropanoic acid Bezafibrate-d6 BEZAFIBRATE EPB(CRM STANDARD) BEZAFIBRATE MM(CRM STANDARD) bezafibrat bezafibrato bf-759 bm15075 ([(Chloro-4-benzamido)-2-ethyl]-4-phenoxy)-2-methylpropionic acid 2-[4-[2-[(4-Chlorobenzoyl)amino]ethyl]phenoxyl]-2-methylpropanoic Acid Befizal Bezatol Difaterol 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]isobutyric Acid 2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropionic acid Bezafibrate,2-[4-[2-(4-Chlorobenzamido)ethyl]phenoxy]-2-methylpropanoic acid 2-[4-[2-(4-CHLOROBENZAMIDO)ETHYL]PHENOXY]-2-METHYLPROPANOIC ACID 2-[4-(2-[4-CHLOROBENZAMIDO]ETHYL)-PHENOXYL]-2-METHYLPROPANOIC ACID 2-[4-(2-[4-CHLOROBENZOMIDO]ETHYL)-PHENOXY]-2-METHYLPROPANOIC ACID 2-(4-(2-((4-CHLOROBENZOYL)AMINO)ETHYL)PHENOXY)-2-METHYLPROPIONIC ACID Propanoic acid, 2-[4-[2-[(4-chlorobenzoyl)amino]ethyl]phenoxy]-2-methyl- Bezafibrate, 98.0%(LC&T Bezafibrate Imp.(EP) AURORA KA-851 BEZAFIBRATE BEZALIP CEDUR 2-(4-(2-((4-chlorobenzoyl)amino)ethyl)phenoxy)-2-methyl-propionicaci 2-(p-(2-(p-chlorobenzamido)ethyl)phenoxy)-2-methylpropionicacid Bezafibrate 41859-67-0 BezafibrateQ: What is Bezafibrate Q: What is the CAS Number of Bezafibrate Q: What is the storage condition of Bezafibrate Q: What are the applications of Bezafibrate Bezafibrate CRS Bezafibrate > Bezabrate 2-[4-[2-[[(4-chlorophenyl)-oxomethyl]amino]ethyl]phenoxy]-2-methylpropanoate Bezafibrate Solution, 100ppm 2-(89-Chlorobenzoyl)benzoic&acid N-(4-Chlorobenzoyl)-Tyramine (Bezafibrate Intermediate) Benzabet Bezafibrate in methanol Bezafibrate 100 μg/ml Acetonitrile 41859-67-0 637927-29-7 1859-67-0 C19H20ClNO4 Cell Biology Cell Signaling and Neuroscience BioChemical Gene Regulation and Expression PPAR and RXR Regulators Intracellular receptor Intermediates & Fine Chemicals Pharmaceuticals Active Pharmaceutical Ingredients Pharmaceutical intermediates Cardiovascular Drugs