(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol

CAS No.: 167354-41-8

Chemical Name:: (2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol

Synonyms: CS-251;Zosuquidar;Unii-ab5K82X98y;Zosuquidar [inn];LY335979; ZOSUQUIDAR;LY335979; LY 335979; LY-335979;(2R)-Anti-5-[3-[4-(10,11-difluoromethanodibenzosuber-5-yl)piperazin-1-yl]-2-hydroxypropoxy]quinoline hydrochloride;(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol;1-Piperazineethanol, 4-[(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-, (αR)-;1-Piperazineethanol, 4-[(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-, (αR)-

CBNumber:: CB12128765

Molecular Formula:: C32H31F2N3O2

Molecular Weight:: 527.6

MOL File:: 167354-41-8.mol

MSDS File:: SDS

Modify Date:: 2023/5/18 11:31:06

Request For Quotation

(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol Properties

Boiling point	690.5±55.0 °C(Predicted)
Density	1.36
storage temp.	-20°C
solubility	H2O: soluble4mg/mL, clear (warmed)
pka	13.94±0.20(Predicted)
form	powder
color	white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
WGK Germany	3

(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SML1044	Zosuquidar hydrochloride ≥98% (HPLC)	167354-41-8	5MG	₹20801.4	2022-06-14	Buy
Sigma-Aldrich(India)	SML1044	Zosuquidar hydrochloride ≥98% (HPLC)	167354-41-8	25MG	₹74558.7	2022-06-14	Buy

Product number	Packaging	Price	Buy
SML1044	5MG	₹20801.4	Buy
SML1044	25MG	₹74558.7	Buy

(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol Chemical Properties,Uses,Production

Uses

Treatment of multidrug resistance (modulator of Pgp resistance).

Biochem/physiol Actions

Zosuqidar is a potent inhibitor of P-glycoprotein (P-gp, MDR1) a transporter protein that is a key modulator of cellular drug efflux. Zosuquidar sensitizes AML, and other cancer cell lines to cytotoxic drugs.

(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol Suppliers

Global( 50)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CONIER CHEM AND PHARMA LIMITED	+8618523575427	China	49391	58	Inquiry
Career Henan Chemica Co	+86-0371-86658258 +8613203830695	China	30253	58	Inquiry
Baoji Guokang Bio-Technology Co., Ltd.	0917-3909592 13892490616	China	9326	58	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	China	49739	58	Inquiry
LEAPCHEM CO., LTD.	+86-852-30606658	China	43348	58	Inquiry
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 18112977050	China	10529	58	Inquiry
Nantong QuanYi Biotechnology Co., Ltd	0513-66337626 18051384581	China	4398	58	Inquiry
Shanghai Maclean Biochemical Technology Co., LTD	021-50706066 15221275939	China	29803	58	Inquiry
RD International Technology Co., Limited	18024082417	China	9155	58	Inquiry

Supplier	Advantage
CONIER CHEM AND PHARMA LIMITED	58
Career Henan Chemica Co	58
Baoji Guokang Bio-Technology Co., Ltd.	58
InvivoChem	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
LEAPCHEM CO., LTD.	58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	58
Nantong QuanYi Biotechnology Co., Ltd	58
Shanghai Maclean Biochemical Technology Co., LTD	58
RD International Technology Co., Limited	58

(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol Spectrum

(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol(167354-41-8)MS

167354-41-8((2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol)Related Search:

ZOSUQUIDAR TRIHYSROCHLORIDE AZD 3759 ZOTAROLIMUS Zonisamide CYCLOHEPTENE

1,1-DIFLUORO-2-PHENYL-CYCLOPROPANE (2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol 1,2-DIPHENYLCYCLOPROPANE (S)-3-(Piperazin-1-yl)propane-1,2-diol ZOSUQUIDAR HYDROCHLORIDE

MS 073 ZOSUQUIDAR MONOHYDRATE 1-(DIBENZOSUBERYL)PIPERAZINE

chevron_left

1of3

chevron_right

(2R)-1-{4-[(1aR,6r,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]piperazin-1-yl}-3-(quinolin-5-yloxy)propan-2-ol Zosuquidar (2R)-Anti-5-[3-[4-(10,11-difluoromethanodibenzosuber-5-yl)piperazin-1-yl]-2-hydroxypropoxy]quinoline hydrochloride Unii-ab5K82X98y Zosuquidar [inn] LY335979; ZOSUQUIDAR CS-251 LY335979; LY 335979; LY-335979 2R)-1-{4-[(1aR,10bS)-1,1-Difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c][7]annulen-6-yl]-1-piperazinyl}-3-(5-quinolinyloxy)-2-propanol trihydrochloride 1-Piperazineethanol, 4-[(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-, (αR)- 1-Piperazineethanol, 4-[(1aα,6α,10bα)-1,1-difluoro-1,1a,6,10b-tetrahydrodibenzo[a,e]cyclopropa[c]cyclohepten-6-yl]-α-[(5-quinolinyloxy)methyl]-, (αR)- 167354-41-8 C32H31F2N3O2