5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID

CAS No.: 118414-59-8

Chemical Name:: 5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID

Synonyms: NTZDPA;5-Chloro-1-(4-chlorobenzyl)-3-(phenylthio)-1H-indole-2-carboxylic acid;5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID;1H-Indole-2-carboxylic acid, 5-chloro-1-[(4-chlorophenyl)methyl]-3-(phenylthio)-

CBNumber:: CB1224807

Molecular Formula:: C22H15Cl2NO2S

Molecular Weight:: 428.33

MOL File:: 118414-59-8.mol

Modify Date:: 2023/6/30 15:45:59

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5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID Properties

storage temp.	Store at +4°C
solubility	DMSO: soluble15mg/mL, clear
form	powder
color	white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P301+P310
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3

5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SML0616	nTZDpa ≥98% (HPLC)	118414-59-8	5MG	₹12394.63	2022-06-14	Buy
Sigma-Aldrich(India)	SML0616	nTZDpa ≥98% (HPLC)	118414-59-8	25MG	₹50076.45	2022-06-14	Buy

Product number	Packaging	Price	Buy
SML0616	5MG	₹12394.63	Buy
SML0616	25MG	₹50076.45	Buy

5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID Chemical Properties,Uses,Production

Uses

nTZDpa is a PPARγ agonist, with pharmaceutical applications such as anti-diabetic drugs.

Biological Activity

Potent, selective non-thiazolidinedione PPAR γ partial agonist (EC 50 = 57 nM); produces ~25% maximum efficacy. Antagonizes full agonist activity by ~60% (IC 50 ~ 285 nM). Displays no activity at PPAR α or PPAR δ receptors. Produces altered receptor conformation, and regulates adipocyte development and gene expression, in a differential manner to full PPAR γ agonists. Modulates metabolism and insulin sensitivity without causing cardiac hypertrophy in mice in vivo .

5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID Suppliers

Global( 31)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
CLEARSYNTH LABS LTD.	+91-22-45045900	Hyderabad, India	6351	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	52927	58	Inquiry
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	China	3336	58	Inquiry
TargetMol Chemicals Inc.	4008200310	China	24647	58	Inquiry
MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	China	4930	55	Inquiry
Labinova AB	+46 (0)8 59032490	Europe	281	64	Inquiry
BIOTREND Chemicals AG	+41 44 805 76 76	Germany	1250	62	Inquiry
Service Chemical Inc.	888-895-6920	Germany	6373	71	Inquiry
Tocris Bioscience	+44 (0) 117 916 3333	United Kingdom	5729	77	Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	China	15848	69	Inquiry

Supplier	Advantage
CLEARSYNTH LABS LTD.	58
Aladdin Scientific	58
Jinan Jiuli Biotechnology Co. , Ltd.	58
TargetMol Chemicals Inc.	58
MQ (shanghai) Pharmaceuticals Co., Ltd.	55
Labinova AB	64
BIOTREND Chemicals AG	62
Service Chemical Inc.	71
Tocris Bioscience	77
3B Pharmachem (Wuhan) International Co.,Ltd.	69

118414-59-8(5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID)Related Search:

5-CHLORO-3-(PHENYLTHIO)-INDOLE 5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID 1-PHENYLMETHYL-1H-INDOLE-2-METHANOL

NTZDPA 5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID 5-Chloro-1-(4-chlorobenzyl)-3-(phenylthio)-1H-indole-2-carboxylic acid 1H-Indole-2-carboxylic acid, 5-chloro-1-[(4-chlorophenyl)methyl]-3-(phenylthio)- 118414-59-8 Intracellular receptor Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals