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5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID

5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID Structure
  • ₹12394.63 - ₹50076.45
  • Product name: 5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID
  • CAS: 118414-59-8
  • MF: C22H15Cl2NO2S
  • MW: 428.33
  • EINECS:
  • MDL Number:MFCD06798322
  • Synonyms:NTZDPA;5-CHLORO-1-[(4-CHLOROPHENYL)METHYL]-3-(PHENYLTHIO)-1H-INDOLE-2-CARBOXYLIC ACID;5-Chloro-1-(4-chlorobenzyl)-3-(phenylthio)-1H-indole-2-carboxylic acid;1H-Indole-2-carboxylic acid, 5-chloro-1-[(4-chlorophenyl)methyl]-3-(phenylthio)-
2 prices
Selected condition:

Brand

  • Sigma-Aldrich(India)

Package

  • 5MG
  • 25MG
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0616
  • Product descriptionnTZDpa ≥98% (HPLC)
  • Packaging25MG
  • Price₹50076.45
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML0616
  • Product descriptionnTZDpa ≥98% (HPLC)
  • Packaging5MG
  • Price₹12394.63
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich(India) SML0616 nTZDpa ≥98% (HPLC) 25MG ₹50076.45 2022-06-14 Buy
Sigma-Aldrich(India) SML0616 nTZDpa ≥98% (HPLC) 5MG ₹12394.63 2022-06-14 Buy

Properties

storage temp. :Store at +4°C
solubility :DMSO: soluble15mg/mL, clear
form :powder
color :white to beige

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
Precautionary statements:
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Description

nTZDpa is a potent, selective non-thiazolidinedione PPARγ partial agonist; with ~25% maximum efficacy. nTZDpa antagonizes full agonist activity by ~60%. Displays no activity at PPARα or PPARδ receptors. Produces altered receptor conformation, and regulates adipocyte development and gene expression, in a differential manner to full PPARγ agonists. nTZDpa modulates metabolism and insulin sensitivity.

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