Choline tosylate

- CAS No.
- 55357-38-5
- Chemical Name:
- Choline tosylate
- Synonyms
- CHOLINE P-TOLUENESULFONATE SALT;2-Hydroxy-N,N,N-triMethylethanaMiniuM 4-Methylbenzenesulfonate;CHOLINE TOSYLATE;Choline p-toluenesulfonate;Choline 4-methylbenzenesulphonate salt;Choline 4-methylbenzenesulphonate salt 99%;(2-Hydroxyethyl)trimethylammonium toluene-4-sulfonate;(2-Hydroxyethyl)trimethylammoniumtoluene-4-sulphonate99%;[2-HYDROXYETHYL]TRIMETHYLAMMONIUM P-TOLUENESULFONATE SALT;(2-Hydroxyethyl)trimethylammonium toluene-4-sulphonate 99%
- CBNumber:
- CB1254402
- Molecular Formula:
- C12H21NO4S
- Molecular Weight:
- 275.36
- MOL File:
- 55357-38-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/5/15 10:43:24
Melting point | 95°C |
---|---|
storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | crystalline solid |
color | White |
Sensitive | Light Sensitive/Hygroscopic |
CAS DataBase Reference | 55357-38-5(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | Xi | |||||||||
Risk Statements | 36/37/38 | |||||||||
Safety Statements | 26-36 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Irritant/Hygroscopic/Light Sensitive | |||||||||
HS Code | 2923900090 | |||||||||
NFPA 704 |
|
Choline tosylate Chemical Properties,Uses,Production
Uses
Choline p-Toluenesulfonate Salt is a useful intermediate as well as a choline acetyltransferase (CHAT) substrate.
Synthesis
A 500 mL reactor was charged at 25 ??C with 50 g (268.5 mmol) methyl tosylate and 100 mL acetone to which a solution of 25.1 g (281.6 mmol) N,N-dimethyl ethanolamine in 50.3 g acetone was added continuously at 25 ??C over 3 h. The dropping funnel was rinsed with additional acetone. The reaction mixture was stirred at 25 ??C for 20 h and the reaction progress was monitored by HPLC. When the level of methyltosylate was lower than 500 ppm the resulting suspension was cooled to 0 ??C over 150 min and the suspension was stirred at 0 ??C for 60 min. The product was collected by fdtration, washed two times with 175 mL acetone and dried under vacuum at 25 ??C to obtain 73.1 g (99 %) of choline tosylate as a white crystalline solid.
Choline tosylate Preparation Products And Raw materials
Choline tosylate Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-+86-371-66670886 | China | 19805 | 58 | Inquiry |
Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 | China | 2176 | 58 | Inquiry |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | China | 49732 | 58 | Inquiry |
Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | China | 12186 | 58 | Inquiry |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | China | 30231 | 58 | Inquiry |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | China | 34563 | 58 | Inquiry |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23541 | 58 | Inquiry |
Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | China | 52849 | 58 | Inquiry |
PT CHEM GROUP LIMITED | +86-85511178; +86-85511178; | China | 35425 | 58 | Inquiry |
GIHI CHEMICALS CO.,LIMITED | +8618058761490 | China | 49984 | 58 | Inquiry |
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