Choline chloride
- CAS No.
- 67-48-1
- Chemical Name:
- Choline chloride
- Synonyms
- Choline Chloride pure;CHOLINE CHLORID;CHOLINE CHLORIDE POWDER;Choline Chloride 60% Corn COB;Lipotril;BIOCOLINA;HEPACHOLINE;HOEtN1,1,1Cl;Cholinchlorid;Cholinii chloridum
- CBNumber:
- CB6166667
- Molecular Formula:
- C5H14ClNO
- Molecular Weight:
- 139.62
- MOL File:
- 67-48-1.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/1 10:09:02
| Melting point | 302-305 °C (dec.) (lit.) |
|---|---|
| Density | 1.0238 (rough estimate) |
| refractive index | 1.5400 (estimate) |
| FEMA | 4500 | Choline chloride (Also Includes Choline) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | H2O: 1 M, clear, colorless |
| form | Adhering Crystals |
| color | White |
| Odor | sl. odor of trimethylamine |
| PH | 5.0-7.5 (25℃, 1M in H2O) |
| Water Solubility | soluble |
| Sensitive | Hygroscopic |
| λmax |
λ: 260 nm Amax: 0.015 λ: 280 nm Amax: 0.010 |
| JECFA Number | 2003 |
| Merck | 14,2206 |
| BRN | 3563126 |
| Stability | Stable. Incompatible with strong oxidizing agents, moisture. Store under a dry atmosphere. |
| InChIKey | SGMZJAMFUVOLNK-UHFFFAOYSA-M |
| LogP | -3.70 |
| CAS DataBase Reference | 67-48-1(CAS DataBase Reference) |
| NIST Chemistry Reference | Choline chloride(67-48-1) |
| EPA Substance Registry System | Choline chloride (67-48-1) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H303-H335 | |||||||||
| Precautionary statements | P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | KH2975000 | |||||||||
| F | 3-9 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29212900 | |||||||||
| Toxicity | LD50 in rats (g/kg): 0.400 i.p.; 6.64 orally (Hartung, Cornish) | |||||||||
| NFPA 704 |
|
Choline chloride price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | W450001 | Choline chloride FCC | 67-48-1 | 1SAMPLE-K | ₹4990.33 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W450001 | Choline chloride FCC | 67-48-1 | 1KG | ₹10749.23 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | W450001 | Choline chloride FCC | 67-48-1 | 5KG | ₹36783.35 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C7527 | Choline chloride BioReagent, suitable for cell culture, suitable for insect cell culture, ≥98% | 67-48-1 | 100G | ₹4503.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | PHR1251 | Choline chloride Pharmaceutical Secondary Standard; Certified Reference Material | 67-48-1 | 500MG | ₹8042.98 | 2022-06-14 | Buy |
Choline chloride Chemical Properties,Uses,Production
Chemical Properties
White crystalline powder
Uses
Choline chloride helps in providing nourishment for pig feed and poultry feed. It acts as a food flavor enhancer. It is used as a precursor of acetylcholine and is a methyl donor in various metabolic processes and in lipid metabolism.
Application
Choline chloride has been used:
as a component of choline acetyltransferase (ChAT) buffer and for choline uptake in cultured human neuroblastoma (SK-N-SH) cells
for choline standard curve generation for quantifying phospholipase D (PLD) activity
as a component of slice solution for the dissection of entorhinal-hippocampal brain slices
Definition
ChEBI: Choline chloride is a quaternary ammonium salt with choline cation and chloride anion. It has a role as an animal growth promotant. It is a chloride salt and a quaternary ammonium salt. It contains a choline.
General Description
Choline chloride appears as white crystals. Practically neutral aqueous solution(NTP, 1992). It is a basic constituent of lecithin that is found in many plants and animal organs. It is important as a precursor of acetylcholine, as a methyl donor in various metabolic processes, and in lipid metabolism.
Air & Water Reactions
Deliquescent. Very soluble in water.
Reactivity Profile
An acidic organic salt. Materials in this group are generally soluble in water. The resulting solutions contain moderate concentrations of hydrogen ions and have pH's of less than 7.0. They react as acids to neutralize bases. These neutralizations generate heat, but less or far less than is generated by neutralization of inorganic acids, inorganic oxoacids, and carboxylic acid. They usually do not react as either oxidizing agents or reducing agents but such behavior is not impossible. Many of these compounds catalyze organic reactions.
Fire Hazard
Choline chloride is relatively nonflammable.
Safety Profile
Poison by intraperitoneal and intravenous routes. Moderately toxic experimentally by ingestion and subcutaneous routes. Mutation data reported. A lipotropic agent which induces the reduction in fats contained in the liver. When heated to decomposition it emits toxic fumes of Cl-, SOx and NOx. See also CHOLINE.
Purification Methods
Extremely deliquescent. Check purity by AgNO3 titration or by titration of OH-base after passage through an anion-exchange column. Crystallise it from absolute EtOH, or EtOH/Et2O, dry it under vacuum and store it in a vacuum desiccator over P2O5 or Mg(ClO4)2. [Beilstein 4 IV 1443.]
Choline chloride Preparation Products And Raw materials
Raw materials
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chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SALVI CHEMICAL | +91-9321313096 +91-9321313096 | Mumbai, India | 26 | 58 | Inquiry |
| CRYSTAL PHARMA | +91-9322218073 +91-9820141331 | Mumbai, India | 106 | 58 | Inquiry |
| VGS SYNTHESIS PRIVATE LIMITED | +91-9866975588 +91-9866975588 | Hyderabad, India | 1818 | 58 | Inquiry |
| oswal chemicals | +91-9173644055 +91-9173644055 | Gujarat, India | 66 | 58 | Inquiry |
| Shreenath Chemicals | +91-8369634120 +91-8369634120 | Maharashtra, India | 48 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| UNILOSA INTERNATINAL PRIVATE LIMITED | +91-9999069917 +91-9999069917 | New Delhi, India | 152 | 58 | Inquiry |
| ShanPar Industries Pvt Ltd | +91-2652638973 +91-9909901206 | Gujarat, India | 115 | 58 | Inquiry |
| Indenta Chemicals (India) Pvt Ltd | +91-2226849600 +91-9326627752 | Maharashtra, India | 48 | 58 | Inquiry |
| Excellent Biotechnologies | +91-8904857846 +91-8032550712 | Karnataka, India | 14 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| SALVI CHEMICAL | 58 |
| CRYSTAL PHARMA | 58 |
| VGS SYNTHESIS PRIVATE LIMITED | 58 |
| oswal chemicals | 58 |
| Shreenath Chemicals | 58 |
| JSK Chemicals | 58 |
| UNILOSA INTERNATINAL PRIVATE LIMITED | 58 |
| ShanPar Industries Pvt Ltd | 58 |
| Indenta Chemicals (India) Pvt Ltd | 58 |
| Excellent Biotechnologies | 58 |
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