Calcium chloride
- CAS No.
- 10043-52-4
- Chemical Name:
- Calcium chloride
- Synonyms
- CaCl2;Anhydrous calcium chloride;CalciuM Cloride;Calcium chloride fused;Calciumchlorid;CALCIUM CHLORIDE POWDER;CALCIUM CHLORIDE FLAKES;Calcium chloride pellets;Calcium chloride,aqueous solution;CALCIUM CHLORIDE POWDER ANHYDROUS
- CBNumber:
- CB3465202
- Molecular Formula:
- CaCl2
- Molecular Weight:
- 110.98
- MOL File:
- 10043-52-4.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/6/22 7:31:40
| Melting point | 772 °C (lit.) |
|---|---|
| Boiling point | 1935 °C/1 atm (lit.) |
| Density | 1.086 g/mL at 20 °C |
| vapor pressure | 0.01 mm Hg ( 20 °C) |
| refractive index |
n |
| Flash point | >1600°C |
| storage temp. | Store at +5°C to +30°C. |
| solubility | H2O: soluble |
| form | powder |
| color | White to gray |
| Specific Gravity | 2.15 |
| PH | 8-10 (100g/l, H2O, 20℃) |
| Water Solubility | 740 g/L (20 ºC) |
| Sensitive | Hygroscopic |
| λmax |
λ: 260 nm Amax: 0.04 λ: 280 nm Amax: 0.02 |
| Merck | 14,1659 |
| Stability | Stable. Incompatible with zinc, water, strong acids, methyl vinyl ether, bromine trifluoride, boron oxide, calcium oxide. Hygroscopic. |
| InChIKey | UXVMQQNJUSDDNG-UHFFFAOYSA-L |
| CAS DataBase Reference | 10043-52-4(CAS DataBase Reference) |
| NIST Chemistry Reference | Calcium dichloride(10043-52-4) |
| EPA Substance Registry System | Calcium chloride (10043-52-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P264-P280-P305+P351+P338-P337+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-36-36/38-41-22 | |||||||||
| Safety Statements | 26-39-24-22-36 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | EV9810000 | |||||||||
| F | 3 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 28272000 | |||||||||
| Toxicity | LD50 i.v. in mice: 42.2 mg/kg (Syed, Hosain) | |||||||||
| NFPA 704 |
|
Calcium chloride price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | C4901 | Calcium chloride anhydrous, powder, ≥97% | 10043-52-4 | 100G | ₹8324.43 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C5670 | Calcium chloride anhydrous, BioReagent, suitable for insect cell culture, suitable for plant cell culture, ≥96.0% | 10043-52-4 | 100G | ₹9580.13 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C4901 | Calcium chloride anhydrous, powder, ≥97% | 10043-52-4 | 500G | ₹24886.68 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C5670 | Calcium chloride anhydrous, BioReagent, suitable for insect cell culture, suitable for plant cell culture, ≥96.0% | 10043-52-4 | 500G | ₹30558.98 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | C4901 | Calcium chloride anhydrous, powder, ≥97% | 10043-52-4 | 1KG | ₹26055.78 | 2022-06-14 | Buy |
Calcium chloride Chemical Properties,Uses,Production
Chemical Properties
Calcium chloride, CaC12, is colorless deliquescent solid that is soluble in water and ethanol. It is formed from the reaction of calcium carbonate and hydrochloric acid or calcium hydroxide and ammonium chloride. It is used in medicine, as an antifreeze, and as a coagulant.
Physical properties
White crystal, powder or flake; highly hygroscopic; the compound and its solutions absorb moisture from the air at various rates depending on calcium chloride concentrations, relative humidity and vapor pressure of water in the air, temperature, surface area of exposed material, and the rate of air circulation; at 40% and 95% relative humidity and 25°C, one gram anhydrous calcium chloride may absorb about 1.4 g and 17 g water, respectively. (Shearer, W. L. 1978 . In Kirk-Othmer Encyclopedia of Chemical Technology, 3rd ed., vol. 4, pp. 432-6. New York: Wiley Interscience); density 2.15, 2.24, 1.85, 1.83 and 1.71 g/cm3 for the anhydrous salt and its mono-, di-, tetra- and hexahydrates, respectively; anhydrous salts melts at 772°C, while the mono-, di-, tetra- and hexahydrates decompose at 260°, 175°, 45.5° and 30°C, respectively; the anhydrous salt vaporizes at 1,935°C; highly soluble in water, moderate to high solubility in alcohol.
Densities and crystallizing temperatures of commercial calcium chloride solutions (Courtesy Allied Corp.):
Occurrence
Calcium chloride may be found in nature as the mineral tachhydrite, CaCl2?2MgCl2?12H2O. It also is found in other minerals. Its concentration in sea water is about 0.15%.
Calcium chloride has several industrial applications. The major applications of this compound are in deicing of roads, dust control, imparting stability to roads and buildings, and to improve traction in tractor tires. It is mixed with ice to make freezing mixtures. Hexahydrate mixed with crushed ice can lower the temperature of the cooling bath to below -50°C. It also is used as a desiccant for dehydrating gases and liquids. It is added to cement in various proportions to manufacture different types of concrete. Other uses are in adhesives, to lower gel temperatures, and as a calcium source in liquid feed supplements for dairy cattle. Also, the compound is used to control particle size development and reduce coalescence in plastics.
Uses
Calcium chloride is highly hygroscopic and is often used as a desiccant.
Preparation
Calcium chloride is obtained as a by-product in the manufacture of sodium carbonate (soda ash) by ammonia-soda (Solvay) process. The process involves the reaction of sodium chloride with calcium carbonate and ammonia. Calcium chloride is currently produced in bulk amounts by evaporation of natural underground brines. In the laboratory, calcium chloride can be prepared by treating limestone with hydrochloric acid followed by evaporation of solution to obtain crystals. The crystals are dehydrated to obtain anhydrous salt. Calcium oxide or hydroxide may be used instead of carbonate.
Definition
calcium chloride: A white deliquescentcompound, CaCl2, which issoluble in water; r.d. 2.15; m.p.782°C; b.p. >1600°C. There are anumber of hydrated forms, includingthe monohydrate, CaCl2.H2O, the dihydrate,CaCl2.2H2O (r.d. 0.84), andthe hexahydrate, CaCl2.6H2O (trigonal;r.d. 1.71; the hexahydrate loses4H2O at 30°C and the remaining2H2O at 200°C). Large quantities of itare formed as a byproduct of theSolvay process and it can be preparedby dissolving calcium carbonateor calcium oxide in hydrochloricacid. Crystals of the anhydrous saltcan only be obtained if the hydratedsalt is heated in a stream of hydrogenchloride. Solid calcium chloride isused in mines and on roads to reducedust problems, whilst the molten saltis the electrolyte in the extraction ofcalcium. An aqueous solution of calciumchloride is used in refrigerationplants.
Production Methods
Calcium chloride is a principal byproduct from the Solvay process.
General Description
Calcium Chloride (CaCl2) is a water soluble ionic crystal with a high enthalpy change of solution. It is majorly derived from limestone and is a by-product of the Solvay process. It is an anhydrous salt that has a hygroscopic nature and can be used as a desiccant.
Air & Water Reactions
Deliquescent. Water soluble. Adding Calcium chloride to hot water caused violent boiling, [MCA Case History No. 69].
Reactivity Profile
Bromine trifluoride rapidly attacks the following salts: barium chloride, cadmium chloride, Calcium chloride, cesium chloride, lithium chloride, silver chloride, rubidium chloride, potassium bromide, potassium chloride, potassium iodide, rhodium tetrabromide, sodium bromide, sodium chloride, and sodium iodide [Mellor 2 Supp. 1:164, 165 1956]. Long term exposure of Calcium chloride solution upon a zinc coated galvanized iron vessel caused slow evolution of hydrogen which ignited and exploded [Bretherick, 5th Ed., 1995].
Health Hazard
Inhalation causes irritation of nose and throat. Ingestion causes irritation of mouth and stomach. Contact with eyes (particularly by dust) causes irritation and possible transient corneal injury. Contact of solid with dry skin causes mild irritation; strong solutions can cause marked irritation, even a superficial burn.
Pharmaceutical Applications
The main applications of calcium chloride as an excipient relate to
its dehydrating properties and, therefore, it has been used as an
antimicrobial preservative, as a desiccant, and as an astringent in
eye lotions.
Therapeutically, calcium chloride injection 10% (as the dihydrate
form) is used to treat hypocalcemia.
Safety Profile
Moderately toxic by ingestion. Poison by intravenous, intramuscular, intraperitoneal, and subcutaneous routes. Human systemic effects: dermatitis, changes in calcium. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. Reacts violently with (B203 + CaO), BrF3. Reaction with zinc releases explosive hydrogen gas. Catalyzes exothermic polymerization of methyl vinyl ether. Exothermic reaction with water. When heated to decomposition it emits toxic fumes of Cl-. See also CALCIUM COMPOUNDS and CHLORIDES.
Safety
Calcium chloride is used in topical, ophthalmic, and injection
preparations. The pure form of calcium chloride is toxic by
intravenous, intramuscular, intraperitoneal, and subcutaneous
routes, and moderately toxic by ingestion, causing stomach and
heart disturbances. It is a severe eye irritant and can cause
dermatitis.
LD50 (mouse, IP): 0.21 g/kg
LD50 (mouse, IV): 0.042 g/kg
LD50 (mouse, oral): 1.94 g/kg
LD50 (mouse, SC): 0.82 g/kg
LD50 (rat, IM): 0.025 g/kg
LD50 (rat, IP): 0.26 g/kg
LD50 (rat, oral): 1.0 g/kg
LD50 (rat, SC): 2.63 g/kg
Potential Exposure
Calcium chloride is used as road salt for melting snow, a drying agent in desiccators, for dehydrating organic liquids and gases, in refrigeration brines and antifreeze, as a dust-proofing agent, food additives, concrete hardening accelerator, and others. May react with strong oxidizers.
storage
Calcium chloride is chemically stable; however, it should be protected from moisture. Store in airtight containers in a cool, dry place.
Shipping
There are no label or maximum shipping quantity requirements set by DOT.
Purification Methods
It is available as fused granules or cubic crystals. It is very hygroscopic, very soluble in H2O (exothermic), and EtOH. Store it in a tightly closed container. [Ehrlich in Handbook of Preparative Inorganic Chemistry (Ed. Brauer) Academic Press Vol I p 931 1963.]
Incompatibilities
Calcium chloride is incompatible with soluble carbonates, phosphates, sulfates, and tartrates. It reacts violently with bromine trifluoride, and a reaction with zinc releases explosive hydrogen gas. It has an exothermic reaction with water, and when heated to decomposition it emits toxic fumes of chlorine.
Regulatory Status
GRAS listed. Included in the FDA Inactive Ingredients Database (injections, ophthalmic preparations, suspensions, creams). Included in medicines licensed in the UK (eye drops; intraocular irrigation; vaccines; injection powders for reconstitution; nebulizer solution; oral suspension).
Calcium chloride Preparation Products And Raw materials
Raw materials
1of2
chevron_rightPreparation Products
1of8
chevron_right| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| SAGAR LIFE SCIENCES PVT LTD | +91-8770359041 +91-8770359041 | Gujarat, India | 79 | 58 | Inquiry |
| SUKHA CHEMICAL INDUSTRIES | +91-9638875444 +91-9638875444 | Gujarat, India | 26 | 58 | Inquiry |
| LABDHI CHEMICAL INDUSTRIES | +91-9322229293 +91-9322229293 | Mumbai, India | 21 | 58 | Inquiry |
| Vardhaman P Golechha | 9704422000 | Telangana, India | 294 | 58 | Inquiry |
| ADVENT CHEMBIO PRIVATE LIMITED | +91-9821524116 +91-9821524116 | Mumbai, India | 353 | 58 | Inquiry |
| S.V ENTERPRISES | +919322701159 | Mumbai, India | 150 | 58 | Inquiry |
| SORBEAD INDIA | +91-9879203377 +91-9879203377 | Gujarat, India | 59 | 58 | Inquiry |
| Choice Chemicals | +91-9895031268 +91-9895031268 | Kerela, India | 118 | 58 | Inquiry |
| JSK Chemicals | +919879767970 | Gujarat, India | 3756 | 58 | Inquiry |
| UNILOSA INTERNATINAL PRIVATE LIMITED | +91-9999069917 +91-9999069917 | New Delhi, India | 152 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| SAGAR LIFE SCIENCES PVT LTD | 58 |
| SUKHA CHEMICAL INDUSTRIES | 58 |
| LABDHI CHEMICAL INDUSTRIES | 58 |
| Vardhaman P Golechha | 58 |
| ADVENT CHEMBIO PRIVATE LIMITED | 58 |
| S.V ENTERPRISES | 58 |
| SORBEAD INDIA | 58 |
| Choice Chemicals | 58 |
| JSK Chemicals | 58 |
| UNILOSA INTERNATINAL PRIVATE LIMITED | 58 |
Related articles
- Properties, Preparation and Ionic Structure of Calcium Chloride
- Calcium Chloride is an ionic compound composed of chlorine and calcium. At room temperature, it appears as a crystalline solid....
- Feb 7，2024
- Preparation and Flame Test of Calcium Chloride
- Calcium chloride is an ionic compound,It is odourless and has a very high enthalpy change of solution. This compound is widely....
- Jan 26，2024
- Calcium Chloride Solution
- The passage introduces the Calcium Chloride Solution.
- Nov 17，2022