N-Allylthiourea
- CAS No.
- 109-57-9
- Chemical Name:
- N-Allylthiourea
- Synonyms
- N-ALLYLTHIOUREA;THIOSINAMINE;Tiosinamine;u19571;U 19571;AMINOSIN;Rhodalin;Rhodallin;RHODALLINE;Thiosinamin
- CBNumber:
- CB3145441
- Molecular Formula:
- C4H8N2S
- Molecular Weight:
- 116.18
- MOL File:
- 109-57-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/5/24 15:44:31
| Melting point | 70-72 °C(lit.) |
|---|---|
| Boiling point | 191.3±33.0 °C(Predicted) |
| Density | 1.11 g/mL at 25 °C(lit.) |
| refractive index | 1.5936 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | H2O: soluble30 parts |
| form | Powder, Crystals, Granules or Chunks |
| pka | 14.57±0.70(Predicted) |
| Specific Gravity | 1.111.219 (20/20℃) |
| color | White to light beige |
| Water Solubility | 67 g/L (20 ºC) |
| Merck | 14,9362 |
| BRN | 1071470 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| InChIKey | HTKFORQRBXIQHD-UHFFFAOYSA-N |
| CAS DataBase Reference | 109-57-9(CAS DataBase Reference) |
| NIST Chemistry Reference | Allylthiourea(109-57-9) |
| EPA Substance Registry System | Allylthiourea (109-57-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301 | |||||||||
| Precautionary statements | P264-P270-P301+P310-P405-P501 | |||||||||
| Hazard Codes | T | |||||||||
| Risk Statements | 25 | |||||||||
| Safety Statements | 45-24/25 | |||||||||
| RIDADR | UN 2811 6.1/PG 3 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | YR8050000 | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29309070 | |||||||||
| Toxicity | LD50 orally in rats: 200 mg/kg (Dieke) | |||||||||
| NFPA 704 |
|
N-Allylthiourea price More Price(8)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | 8.08158 | N-Allylthiourea for synthesis | 109-57-9 | 25G | ₹3270.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.08158 | N-Allylthiourea for synthesis | 109-57-9 | 50G | ₹4180 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 8.08158 | N-Allylthiourea for synthesis | 109-57-9 | 250G | ₹11390.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 108804 | N-Allylthiourea 98% | 109-57-9 | 50G | ₹4449.08 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 108804 | N-Allylthiourea 98% | 109-57-9 | 250G | ₹13433.83 | 2022-06-14 | Buy |
N-Allylthiourea Chemical Properties,Uses,Production
Chemical Properties
white crystals or powder. Melting point 76～78.5 ℃, relative density is 1.110, soluble in water and ethanol, slightly soluble in ethanol, insoluble in benzene, with a garlic odor. It is used as an additive for cyanide-free copper plating to increase the brightness and corrosion resistance of plated products.
Uses
N-Allylthiourea is a nitrification inhibitor used in the study on the transformation of diclofenac, naproxen and bisoprolol under aerobic and anaerobic conditions. It is also used in medicine to minimize scar tissue in order to fight against a type of dermatitis. Further, it inhibits the growth of transplanted tumors in mice. It acts as a chelating agent. In addition, it is used in cosmetics, preservative and in organic synthesis.
Preparation
In the presence of potassium iodide, in ethanol solution, chloropropene is reacted with sodium thiocyanide to form allyl isothiocyanate, which is then ammoniated in ammonium hydroxide solution, concentrated, cooled and crystallized, filtered, washed, and recrystallized in ethanol or water to produce Allylthiourea.
Definition
ChEBI: Allylthiourea is a thiourea with a prop-2-enyl group attached to one of the amines. It has a role as a metabolite. It is functionally related to a thiourea.
General Description
White crystalline solid with a slight garlic odor.
Air & Water Reactions
Soluble in water.
Reactivity Profile
Allylthiourea may react vigorously with strong oxidizing agents. Can react exothermically with reducing agents (such as alkali metals and hydrides) to release gaseous hydrogen. May react exothermically with both acids and bases. May generate flammable gases in combination with aldehydes, nitrides, and hydrides. Incompatible with peroxides and acid halides.
Health Hazard
SYMPTOMS: Contact eczema due to sensitization in humans has been reported.
Fire Hazard
Flash point data are not available for Allylthiourea, but Allylthiourea is probably combustible.
Purification Methods
Recrystallise it from H2O. It is soluble in 30 parts of cold H2O, and it is soluble in EtOH but insoluble in *C6H6. It has also been recrystallised from acetone, EtOH or ethyl acetate, after decolorising with charcoal. The white crystals have a bitter taste with a slight garlic odour and are TOXIC. An unstable crystalline form is obtained by recrystallising from the melt. [McCrone et al. Anal Chem 21 421 1949, Beilstein 4 IV 1072.]
N-Allylthiourea Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| LOBA CHEMIE PVT.LTD. | 91-22-6663 6699 | Mumbai, India | 3077 | 58 | Inquiry |
| Ultra Pure Lab Chem Industries LLP | 08046077962 | Mumbai, India | 252 | 58 | Inquiry |
| HiMedia Laboratories | 91-22-61471919 | Maharashtra, India | 1843 | 58 | Inquiry |
| Grr Fine Chem/Grr Exports | 91-79-40031771 | Gujarat, India | 405 | 58 | Inquiry |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9626 | 58 | Inquiry |
| Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | China | 12460 | 58 | Inquiry |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | China | 3002 | 58 | Inquiry |
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