ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >5-chloro-2,3-diphenylpyrazine
5-chloro-2,3-diphenylpyrazine
![5-chloro-2,3-diphenylpyrazine Structure](CAS/20150408/GIF/41270-66-0.gif)
- CAS No.
- 41270-66-0
- Chemical Name:
- 5-chloro-2,3-diphenylpyrazine
- Synonyms
- Selexipag Impurity 31;2-Chloro-5,6-diphenylpyrazine;Pyrazine, 5-chloro-2,3-diphenyl-;chloro-2,3-diphenylpyrazine (Selexipag Intermediate)
- CBNumber:
- CB12676877
- Molecular Formula:
- C16H11ClN2
- Molecular Weight:
- 266.72
- MOL File:
- 41270-66-0.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/1 10:00:58
Melting point | 126-128℃ (methanol ) |
---|---|
Boiling point | 145°C/0.001mmHg(lit.) |
Density | 1?+-.0.06 g/cm3(Predicted) |
pka | -2.16±0.10(Predicted) |
form | powder to crystal |
color | White to Orange to Green |
InChI | InChI=1S/C16H11ClN2/c17-14-11-18-15(12-7-3-1-4-8-12)16(19-14)13-9-5-2-6-10-13/h1-11H |
InChIKey | VUGNCPVAXWZTOL-UHFFFAOYSA-N |
SMILES | C1(C2=CC=CC=C2)=NC=C(Cl)N=C1C1=CC=CC=C1 |
CAS DataBase Reference | 41270-66-0 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319-H413 | |||||||||
Precautionary statements | P501-P273-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
HS Code | 2933.99.5300 | |||||||||
NFPA 704 |
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5-chloro-2,3-diphenylpyrazine price More Price(2)
5-chloro-2,3-diphenylpyrazine Chemical Properties,Uses,Production
Uses
2-Chloro-5,6-diphenylpyrazine is a diphenylpyrazine derivative used in a study to determine a novel class of prostacyclin receptor agonists.
Synthesis
50 gm of 2-hydroxy-5,6-diphenylpyrazine obtained was treated with 250 ml of POCI3 and then heated the reaction mixture at 100-110 °C with stirring for 5-6 hrs. The reaction mixture was cooled to room temperature and poured in 1000 ml of ice water at 0-5 °C and maintained with stirring for 60 minutes. The solid obtained was filtered, washed with water and dried to obtain 41.3 gm of 5-chloro-2,3-diphenylpyrazine. Yield: 77.00 percent.
5-chloro-2,3-diphenylpyrazine Preparation Products And Raw materials
Global( 184)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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VASUDHA PHARMA CHEM LIMITED | +91-91-4044763666 +91-9396659284 | Telangana, India | 102 | 58 | Inquiry |
Viyash Life Sciences Pvt Ltd | +91-4023635052 +91-4023635052 | Telangana, India | 213 | 58 | Inquiry |
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Trimax bio sciences private ltd | +91-8532299988 +91-8532299988 | Karnataka, India | 36 | 58 | Inquiry |
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Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | China | 39916 | 58 | Inquiry |
Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 | China | 1000 | 58 | Inquiry |
41270-66-0(5-chloro-2,3-diphenylpyrazine)Related Search:
Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-
2-Pyrazinamine, N-(1-methylethyl)-5,6-diphenyl-
5,6-DIPHENYLPYRAZIN-2-OL
N-(methylsulfonyl)glycine
2,3-Dichloro-5,6-diphenylpyrazine
1-Butanol, 4-[(5,6-diphenyl-2-pyrazinyl)oxy]-
2,3-DIPHENYLPYRAZINE
Bromoacetic acid
2-T-BUTYL GLYCOLATE
4-(Isopropylamino)butanol
Acetic acid, 2-[4-[(5,6-diphenyl-2-pyrazinyl)oxy]butoxy]-, 1,1-dimethylethyl ester
( 2-{4-[N-(5,6-diphenylpyrazin-2-yl)-N-isopropylamino]butyloxy}acetic acid tert-butylester )
SELEXIPAG interMediate
[4-[(5,6-DIPHENYLPYRAZINYL)(1-METHYLETHYL)AMINO]BUTOXY]-ACETIC ACID
Acetamide, 2-[4-[(1-methylethyl)amino]butoxy]-N-(methylsulfonyl)-
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2-Chloro-5,6-diphenylpyrazine
Pyrazine, 5-chloro-2,3-diphenyl-
Selexipag Impurity 31
chloro-2,3-diphenylpyrazine
(Selexipag Intermediate)
41270-66-0
Selexipag intermediate