ChemicalBook > Product Catalog >Analytical Chemistry >Standard >Pharmaceutical Impurity Reference Standards >2-Hydroxy Atorvastatin Calcium Salt
2-Hydroxy Atorvastatin Calcium Salt
- CAS No.
- 265989-46-6
- Chemical Name:
- 2-Hydroxy Atorvastatin Calcium Salt
- Synonyms
- Atorvastatin Impurity K;2-Hydroxy Atorvastatin Sodium;2-Hydroxy Atorvastatin CalciuM Salt;di(2-Hydroxy Atorvastatin) CalciuM Salt;inhibit,2-Hydroxy atorvastatin,2Hydroxy atorvastatin calcium salt,Drug Metabolite,Inhibitor,2 Hydroxy atorvastatin calcium salt;calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate;Atorvastatin impurity 39/Atorvastatin 2-Hydroxy Calcium Salt/ortho-Hydroxy Atorvastatin Calcium Salt/(3R,5R)-7-[3-(2-Hydroxyphenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt;2-Hydroxy Atorvastatin Calcium SaltQ: What is 2-Hydroxy Atorvastatin Calcium Salt Q: What is the CAS Number of 2-Hydroxy Atorvastatin Calcium Salt Q: What is the storage condition of 2-Hydroxy Atorvastatin Calcium Salt Q: What are the applications of 2-Hydroxy Atorvastatin Calcium Salt;2-Hydroxy Atorvastatin D5 Calcium SaltQ: What is 2-Hydroxy Atorvastatin D5 Calcium Salt Q: What is the CAS Number of 2-Hydroxy Atorvastatin D5 Calcium Salt Q: What is the storage condition of 2-Hydroxy Atorvastatin D5 Calcium Salt Q: What are the applications of 2-Hydroxy Atorvastatin D5 Calcium Salt
- CBNumber:
- CB12709452
- Molecular Formula:
- C33H37CaFN2O6
- Molecular Weight:
- 616.74
- MOL File:
- 265989-46-6.mol
- Modify Date:
- 2024/5/6 11:59:17
2-Hydroxy Atorvastatin Calcium Salt Chemical Properties,Uses,Production
Chemical Properties
White to Pale Yellow Solid
Uses
di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Biological Activity
2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM. It inhibits lipid hydroperoxide formation and copper sulfate-induced thiobarbituric acid reactive substances (TBARS) formation in 1,2-dilinoleoyl-sn-glycero-3-PC (DLPC) vesicles and human LDL, respectively, in a concentration-dependent manner. 2-Hydroxy Atorvastatin reduces cell death induced by oxygen-glucose deprivation (OGD) in primary rat cortical neurons and increases phosphorylation of cAMP-response-element-binding protein (CREB) in GABAergic neurons when used at a concentration of 600 nM following OGD.
2-Hydroxy Atorvastatin Calcium Salt Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 59)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Chemicea Pharmaceuticals Pvt Ltd | +91-918482849343 +91-8482849343 | Mumbai, India | 461 | 58 | Inquiry |
| Varanous Labs Pvt Ltd | +91-7036248882 +91-7036248882 | Hyderabad, India | 1541 | 58 | Inquiry |
| CLEARSYNTH LABS LTD. | +91-22-45045900 | Hyderabad, India | 6351 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Chemicea Pharmaceuticals Pvt Ltd | +91-9881765045/+91-8796656135 | Pune, India | 825 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
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| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | China | 23555 | 58 | Inquiry |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | China | 9640 | 58 | Inquiry |
| CR Corporation Limited | +8613062833949 | China | 8647 | 58 | Inquiry |
265989-46-6(2-Hydroxy Atorvastatin Calcium Salt)Related Search:
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Ortho-Hydroxy atorvastatin calcium salt
O-HYDROXY ATORVASTATIN LACTONE
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2-Hydroxy Atorvastatin CalciuM Salt
2-Hydroxy Atorvastatin Sodium
Atorvastatin Impurity K
Atorvastatin impurity 39/Atorvastatin 2-Hydroxy Calcium Salt/ortho-Hydroxy Atorvastatin Calcium Salt/(3R,5R)-7-[3-(2-Hydroxyphenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt
calcium,(3S,5S)-7-[2-(4-fluorophenyl)-4-[(2-hydroxyphenyl)carbamoyl]-3-phenyl-5-propan-2-ylpyrrol-1-yl]-3,5-dihydroxyheptanoate
2-Hydroxy Atorvastatin D5 Calcium SaltQ: What is
2-Hydroxy Atorvastatin D5 Calcium Salt Q: What is the CAS Number of
2-Hydroxy Atorvastatin D5 Calcium Salt Q: What is the storage condition of
2-Hydroxy Atorvastatin D5 Calcium Salt Q: What are the applications of
2-Hydroxy Atorvastatin D5 Calcium Salt
2-Hydroxy Atorvastatin Calcium SaltQ: What is
2-Hydroxy Atorvastatin Calcium Salt Q: What is the CAS Number of
2-Hydroxy Atorvastatin Calcium Salt Q: What is the storage condition of
2-Hydroxy Atorvastatin Calcium Salt Q: What are the applications of
2-Hydroxy Atorvastatin Calcium Salt
inhibit,2-Hydroxy atorvastatin,2Hydroxy atorvastatin calcium salt,Drug Metabolite,Inhibitor,2 Hydroxy atorvastatin calcium salt
di(2-Hydroxy Atorvastatin) CalciuM Salt
265989-46-6
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