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ChemicalBook > Product Catalog >Biochemical Engineering >Inhibitors >Cell Cycle >PLK inhibitors >NMS-P937 (NMS1286937)

NMS-P937 (NMS1286937)

NMS-P937 (NMS1286937) Structure
CAS No.
1034616-18-6
Chemical Name:
NMS-P937 (NMS1286937)
Synonyms
PCM075;CS-1243;PCM 075;PCM-075;NMS-P937;NMS-1286937;NMS-1286937,NMS-P937;NMS-P937 (NMS1286937);Onvansertib (NMS-P937);Onvansertib（NMS-1286937
CBNumber:
CB12715659
Molecular Formula:
C24H27F3N8O3
Molecular Weight:
532.52
MOL File:
1034616-18-6.mol
Modify Date:
2025/4/28 21:36:36
Request For Quotation

NMS-P937 (NMS1286937) Properties

Boiling point 757.8±70.0 °C(Predicted)
Density 1.57±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility insoluble in H2O; insoluble in EtOH; ≥13.33 mg/mL in DMSO
form solid
pka 14.29±0.10(Predicted)
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
NFPA 704
0
2 0

NMS-P937 (NMS1286937) Chemical Properties,Uses,Production

Uses

NMS-P937 is a quinazoline derivative that is a potent and selective Polo-like kinase 1 inhibitor. Antitumor, anti-cancer.

NMS-P937 (NMS1286937) Preparation Products And Raw materials

Raw materials

Preparation Products

NMS-P937 (NMS1286937) Suppliers

Global( 119)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6739 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6754 58 Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 33024 60 Inquiry
BOC Sciences +1-631-485-4226 United States 19552 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 32222 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 22855 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10473 58 Inquiry
InvivoChem +1-708-310-1919 +1-13798911105 United States 6391 58 Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49734 58 Inquiry
Nantong HI-FUTURE Biology Co., Ltd. +undefined18051384581 China 3135 58 Inquiry
Supplier Advantage
Pharmaffiliates Analytics and Synthetics P. Ltd 58
Pharma Affiliates 58
ATK CHEMICAL COMPANY LIMITED 60
BOC Sciences 58
TargetMol Chemicals Inc. 58
Dideu Industries Group Limited 58
Zhejiang J&C Biological Technology Co.,Limited 58
InvivoChem 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Nantong HI-FUTURE Biology Co., Ltd. 58

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NMS-1286937 4,5-Dihydro-1-(2-hydroxyethyl)-8-[[5-(4-methyl-1-piperazinyl)-2-(trifluoromethoxy)phenyl]amino]-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide NMS-P937 (NMS1286937) NMS-P937 NMS-1286937,NMS-P937 1-(2-hydroxyethyl)-8-[5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)anilino]-4,5-dihydropyrazolo[4,3-h]quinazoline-3-carboxamide CS-1243 1H-Pyrazolo[4,3-h]quinazoline-3-carboxamide, 4,5-dihydro-1-(2-hydroxyethyl)-8-[[5-(4-methyl-1-piperazinyl)-2-(trifluoromethoxy)phenyl]amino]- NMS-P937 (NMS1286937) USP/EP/BP Onvansertib（NMS-1286937 1-(2-Hydroxyethyl)-8-[[5-(4-methyl-1-piperazinyl)-2-(trifluoromethoxy)phenyl]amino]-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide Onvansertib (NMS-P937) PCM 075 PCM075 PCM-075 Onvansertib, 10 mM in DMSO 1034616-18-6 C24H27F3N8O3 Inhibitors