"6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
- CAS No.
- 14892-97-8
- Chemical Name:
- "6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
- Synonyms
- -2-suL;6,7-diphenyL;SCR7 pyrazine;SCR7; SCR-7; SCR 7.;6,7-Diphenyl-2-thiolumazine;6,7-Diphenyl-2-sulfanylpteridin-4-ol;"6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one;2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone;6,7-Diphenyl-2-thioxo-2,3-dihydropteridin-4(1H)-one;6,7-Diphenyl-2-thioxo-2,3-dihydropteridin-4(8H)-one
- CBNumber:
- CB12741690
- Molecular Formula:
- C18H12N4OS
- Molecular Weight:
- 332.38
- MOL File:
- 14892-97-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
| Melting point | 209 °C |
|---|---|
| Density | 1.42±0.1 g/cm3(Predicted) |
| storage temp. | room temp |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.14±0.60(Predicted) |
| form | powder |
| color | faintly yellow to dark yellow |
| CAS DataBase Reference | 14892-97-8 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P301+P312+P330 |
| HS Code | 2933.59.8000 |
"6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SML1546 | SCR7 pyrazine ≥98% (HPLC) | 14892-97-8 | 5MG | ₹11643.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SML1546 | SCR7 pyrazine ≥98% (HPLC) | 14892-97-8 | 25MG | ₹45177 | 2022-06-14 | Buy |
| TCI Chemicals (India) | C3577 | SCR7 Pyrazine | 14892-97-8 | 10MG | ₹6000 | 2022-05-26 | Buy |
| TCI Chemicals (India) | C3577 | SCR7 Pyrazine | 14892-97-8 | 50MG | ₹14800 | 2022-05-26 | Buy |
"6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one Chemical Properties,Uses,Production
Uses
SCR7 pyrazine has been used as a non-homologous end joining (NHEJ) modulator to study its effect on CRISPR/Cas9-mediated editing.
General Description
SCR7 pyrazine is an inhibitor of DNA ligase IV.
Biochem/physiol Actions
SCR7 pyrazine is reported to be an inhibitor of non-homologous end joining (NHEJ) and has been shown to enhance the efficiency of CRISPR-Cas9 genome editing. The effect of SCR7 pyrazine on the efficiency and targeting precision of CRISPR applications has been shown to be cell type specific and context dependent. SCR7 pyrazine is a product of spontaneous cyclization of SCR7, first reported by Srivastava, M., et al.
"6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 81)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| BOC Sciences | +1-631-485-4226 | United States | 19553 | 58 | Inquiry |
| career henan chemical co | +86-0371-86658258 +8613203830695 | China | 29825 | 58 | Inquiry |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | China | 5738 | 58 | Inquiry |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | United States | 19892 | 58 | Inquiry |
| InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | China | 11681 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
"6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
6,7-Diphenyl-2-thiolumazine
SCR7 pyrazine
6,7-Diphenyl-2-sulfanylpteridin-4-ol
2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone
SCR7; SCR-7; SCR 7.
6,7-diphenyL
4(1H)-Pteridinone, 2,3-dihydro-6,7-diphenyl-2-thioxo-
-2-suL
6,7-Diphenyl-2-thioxo-2,3-dihydropteridin-4(8H)-one
6,7-Diphenyl-2-thioxo-2,3-dihydropteridin-4(1H)-one
phosphorylation,nonhomologous,Caspase 9,Inhibitor,gene,DNA/RNA Synthesis,end-joining,Apoptosis,DNA,SCR7 pyrazine,replacement,SCR-7 pyrazine,CRISPR/Cas9,ligase-IV,Caspase 3,inhibit,anticancer
14892-97-8