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"6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one

  • ₹6000 - ₹45177
  • Product name: "6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one
  • CAS: 14892-97-8
  • MF: C18H12N4OS
  • MW: 332.38
  • EINECS:-0
  • MDL Number:MFCD02167478
  • Synonyms:"6,7-diphenyl-2-sulfanylidene-1H-pteridin-4-one;6,7-Diphenyl-2-thiolumazine;SCR7 pyrazine;6,7-Diphenyl-2-sulfanylpteridin-4-ol;2,3-Dihydro-6,7-diphenyl-2-thioxo-4(1H)-pteridinone;SCR7; SCR-7; SCR 7.;6,7-diphenyL;4(1H)-Pteridinone, 2,3-dihydro-6,7-diphenyl-2-thioxo-
4 prices
Selected condition:

Brand

  • TCI Chemicals (India)
  • Sigma-Aldrich(India)

Package

  • 5MG
  • 10MG
  • 25MG
  • 50MG
  • ManufacturerTCI Chemicals (India)
  • Product numberC3577
  • Product descriptionSCR7 Pyrazine
  • Packaging10MG
  • Price₹6000
  • Updated2022-05-26
  • Buy
  • ManufacturerTCI Chemicals (India)
  • Product numberC3577
  • Product descriptionSCR7 Pyrazine
  • Packaging50MG
  • Price₹14800
  • Updated2022-05-26
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1546
  • Product descriptionSCR7 pyrazine ≥98% (HPLC)
  • Packaging5MG
  • Price₹11643.9
  • Updated2022-06-14
  • Buy
  • ManufacturerSigma-Aldrich(India)
  • Product numberSML1546
  • Product descriptionSCR7 pyrazine ≥98% (HPLC)
  • Packaging25MG
  • Price₹45177
  • Updated2022-06-14
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
TCI Chemicals (India) C3577 SCR7 Pyrazine 10MG ₹6000 2022-05-26 Buy
TCI Chemicals (India) C3577 SCR7 Pyrazine 50MG ₹14800 2022-05-26 Buy
Sigma-Aldrich(India) SML1546 SCR7 pyrazine ≥98% (HPLC) 5MG ₹11643.9 2022-06-14 Buy
Sigma-Aldrich(India) SML1546 SCR7 pyrazine ≥98% (HPLC) 25MG ₹45177 2022-06-14 Buy

Properties

Melting point :209 °C
Density :1.42±0.1 g/cm3(Predicted)
storage temp. :room temp
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
pka :4.14±0.60(Predicted)
color :faintly yellow to dark yellow
CAS DataBase Reference :14892-97-8

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
Precautionary statements:

Description

DNA ligase IV seals double-strand breaks during the process of nonhomologous end-joining in DNA repair. Inhibiting this function in cancer cells is one strategy to prevent deleterious cell growth. SCR7 pyrazine is a small molecule inhibitor of DNA ligase IV that prevents nonhomologous end-joining by interfering with ligase binding and activating apoptosis. It also inhibits ligase III, but does not affect the activity of T4 DNA ligase or ligase I. SCR7 pyrazine has been used to increase the rate of homology directed repair triggered by DNA double-strand breaks and to inhibit cancer cell growth in vitro (IC50s = 8-120 μM) and in mouse models when co-administered with double-strand break-inducing therapeutic compounds.