[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
![[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Structure](CAS/20180629/GIF/1360705-96-9.gif)
- CAS No.
- 1360705-96-9
- Chemical Name:
- [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
- Synonyms
- ML 210;CID 49766530;ML 210 >=98% (HPLC);ML 210 - CID 49766530;[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone;(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone;Methanone, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-;[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone;residue,Ferroptosis,inhibit,peroxidase,ML-210,Covalent,selenocysteine,Glutathione Peroxidase,ML 210,ML210,glutathione,Inhibitor,GPX4,anti-cancer
- CBNumber:
- CB12750494
- Molecular Formula:
- C22H20Cl2N4O4
- Molecular Weight:
- 475.32
- MOL File:
- 1360705-96-9.mol
- MSDS File:
- SDS
- Modify Date:
- 2023/6/30 15:45:59
[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Properties
Boiling point | 644.7±55.0 °C(Predicted) |
---|---|
Density | 1.415±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | Soluble in DMSO (up to 30 mg/ml) |
pka | 4.69±0.10(Predicted) |
form | powder |
color | white to beige |
Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months. |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H302 | |||||||||
Precautionary statements | P280-P305+P351+P338 | |||||||||
WGK Germany | 3 | |||||||||
NFPA 704 |
|
[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone price More Price(2)
[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Chemical Properties,Uses,Production
Uses
ML 210 has been used as a glutathione peroxidase 4 (GPX4) inhibitor to induce ferroptosis in cancer cells. It has also been used as a GPX4 inhibitor to examine whether pharmacological inhibition of GPX4 altered prominin2 expression and impacted ferroptosis in adherent MCF10A and Hs578t cells.
Biochem/physiol Actions
ML 210 induces non-apoptotic cell death in tumor cells expressing the RAS oncogene.
[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Preparation Products And Raw materials
[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Suppliers
Global( 53)Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
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ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
InvivoChem | +1-708-310-1919 +1-13798911105 | United States | 6393 | 58 | Inquiry |
TargetMol Chemicals Inc. | +1-781-999-5354 | United States | 19973 | 58 | Inquiry |
Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | China | 33350 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 57511 | 58 | Inquiry |
Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | China | 5225 | 58 | Inquiry |
InvivoChem | 13549236410 | China | 6755 | 58 | Inquiry |
Olix (Shanghai) Pharmaceutical Technology Co., Ltd | 17316404525 | China | 9721 | 58 | Inquiry |
Henan Alpha Chemical Co., Ltd. | 0371-55013243 15324716602 | China | 10010 | 58 | Inquiry |
Guangzhou Younan Technology Co., Ltd | 020-020-82000279 18988968278 | China | 4297 | 58 | Inquiry |
1360705-96-9([4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone)Related Search:
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[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone
CID 49766530
ML 210
[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone
ML 210 - CID 49766530
Methanone, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-
ML 210 >=98% (HPLC)
(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone
residue,Ferroptosis,inhibit,peroxidase,ML-210,Covalent,selenocysteine,Glutathione Peroxidase,ML 210,ML210,glutathione,Inhibitor,GPX4,anti-cancer
1360705-96-9