[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone

CAS No.: 1360705-96-9

Chemical Name:: [4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone

Synonyms: ML 210;CID 49766530;ML 210 >=98% (HPLC);ML 210 - CID 49766530;[4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone;(4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone;Methanone, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)-;[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone;residue,Ferroptosis,inhibit,peroxidase,ML-210,Covalent,selenocysteine,Glutathione Peroxidase,ML 210,ML210,glutathione,Inhibitor,GPX4,anti-cancer

CBNumber:: CB12750494

Molecular Formula:: C22H20Cl2N4O4

Molecular Weight:: 475.32

MOL File:: 1360705-96-9.mol

MSDS File:: SDS

Modify Date:: 2023/6/30 15:45:59

Request For Quotation

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Properties

Boiling point	644.7±55.0 °C(Predicted)
Density	1.415±0.06 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Soluble in DMSO (up to 30 mg/ml)
pka	4.69±0.10(Predicted)
form	powder
color	white to beige
Stability	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P280-P305+P351+P338

WGK Germany

NFPA 704

	0
2		0

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich(India)	SML0521	ML 210 ≥98% (HPLC)	1360705-96-9	5MG	₹12394.63	2022-06-14	Buy
Sigma-Aldrich(India)	SML0521	ML 210 ≥98% (HPLC)	1360705-96-9	25MG	₹50076.45	2022-06-14	Buy

Product number	Packaging	Price	Buy
SML0521	5MG	₹12394.63	Buy
SML0521	25MG	₹50076.45	Buy

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Chemical Properties,Uses,Production

Uses

ML 210 has been used as a glutathione peroxidase 4 (GPX4) inhibitor to induce ferroptosis in cancer cells. It has also been used as a GPX4 inhibitor to examine whether pharmacological inhibition of GPX4 altered prominin2 expression and impacted ferroptosis in adherent MCF10A and Hs578t cells.

Biochem/physiol Actions

ML 210 induces non-apoptotic cell death in tumor cells expressing the RAS oncogene.

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Preparation Products And Raw materials

Raw materials

5-METHYL-4-NITRO-3-ISOXAZOLECARBOXYLIC ACID

Preparation Products

[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone Suppliers

Global( 53)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	China	32836	60	Inquiry
InvivoChem	+1-708-310-1919 +1-13798911105	United States	6393	58	Inquiry
TargetMol Chemicals Inc.	+1-781-999-5354	United States	19973	58	Inquiry
Shanghai Acmec Biochemical Technology Co., Ltd.	+undefined18621343501	China	33350	58	Inquiry
Aladdin Scientific	+1-+1(833)-552-7181	United States	57511	58	Inquiry
Wuhan Jingkang en Biomedical Technology Co., Ltd	+8613720134139	China	5225	58	Inquiry
InvivoChem	13549236410	China	6755	58	Inquiry
Olix (Shanghai) Pharmaceutical Technology Co., Ltd	17316404525	China	9721	58	Inquiry
Henan Alpha Chemical Co., Ltd.	0371-55013243 15324716602	China	10010	58	Inquiry
Guangzhou Younan Technology Co., Ltd	020-020-82000279 18988968278	China	4297	58	Inquiry

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
InvivoChem	58
TargetMol Chemicals Inc.	58
Shanghai Acmec Biochemical Technology Co., Ltd.	58
Aladdin Scientific	58
Wuhan Jingkang en Biomedical Technology Co., Ltd	58
InvivoChem	58
Olix (Shanghai) Pharmaceutical Technology Co., Ltd	58
Henan Alpha Chemical Co., Ltd.	58
Guangzhou Younan Technology Co., Ltd	58

1360705-96-9([4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone)Related Search:

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[4-[Bis(4-chlorophenyl)methyl]piperazin-1-yl]-(5-methyl-4-nitro-1,2-oxazol-3-yl)methanone CID 49766530 ML 210 [4-[Bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)methanone ML 210 - CID 49766530 Methanone, [4-[bis(4-chlorophenyl)methyl]-1-piperazinyl](5-methyl-4-nitro-3-isoxazolyl)- ML 210 >=98% (HPLC) (4-(Bis(4-chlorophenyl)methyl)piperazin-1-yl)(5-methyl-4-nitroisoxazol-3-yl)methanone residue,Ferroptosis,inhibit,peroxidase,ML-210,Covalent,selenocysteine,Glutathione Peroxidase,ML 210,ML210,glutathione,Inhibitor,GPX4,anti-cancer 1360705-96-9