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RO-31-7549

RO-31-7549 Structure
CAS No.
125313-65-7
Chemical Name:
RO-31-7549
Synonyms
RO-31-7549;RO 31-7549 ACETATE SALT;Bisindolylmaleimide VIII;BISINDOLYLMALEIMIDE VIII ACETATE;BIDINDOLYLMALEIMIDE VIII, ACETETE;Ro-31-7549, Monohydrate - CAS 125313-65-7 - Calbiochem;2-[1-3(AMINOPROPYL)INDOL-3-YL]-3(1-METHYL-1H-INDOL-3-YL)MALEIMIDE, ACETATE;3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 3-(1-(3-aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-
CBNumber:
CB1281637
Molecular Formula:
C24H22N4O2
Molecular Weight:
398.46
MOL File:
125313-65-7.mol
Modify Date:
2023/4/23 13:52:06
Request For Quotation

RO-31-7549 Properties

storage temp. −20°C
solubility DMSO: soluble
form Red to reddish-orange solid

SAFETY

Risk and Safety Statements

WGK Germany  3

RO-31-7549 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) 557508 Ro-31-7549, Monohydrate - CAS 125313-65-7 - Calbiochem A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC?? = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. 125313-65-7 1MG ₹17860 2022-06-14 Buy
Product number Packaging Price Buy
557508 1MG ₹17860 Buy

RO-31-7549 Chemical Properties,Uses,Production

Uses

It is a potent inhibitor of protein kinase C (PKC) activity.

General Description

A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC50 = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. Does not inhibit the tyrosine phosphorylation or the activation of phospholipase Cγ1. Exhibits some degree of PKC isozyme specificity (IC50 = 53 nM for PKCα, 195 nM for PKCβI, 163 nM for PKCβII, 213 nM for PKCγ, and 175 nM for PKCε). Inhibits carbachol-evoked noradrenaline release (IC50 = 600 nM).

Biochem/physiol Actions

Cell permeable: yes

RO-31-7549 Preparation Products And Raw materials

Raw materials

Preparation Products

RO-31-7549 Suppliers

Global( 39)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 China 49739 58 Inquiry
Sigma-Aldrich 021-61415566 800-8193336 China 51471 80 Inquiry
TargetMol Chemicals Inc. 15002134094 China 28118 58 Inquiry
Alexis Corporation +41 61 926 8989 Switzerland 3599 74 Inquiry
Nacalai Tesque, Inc. 81 75 251 1723 Japan 6048 75 Inquiry
Kanto Chemical Co., Inc. +81 3 3663 7631 Japan 6762 74 Inquiry
EMD Biosciences, Inc. 858 450 5500 United States 6529 66 Inquiry
VWR International 800 932 5000 United Kingdom 6554 82 Inquiry
Apollo Scientific Ltd. 44 161 406 0505 United Kingdom 6097 88 Inquiry
AXXORA, LLC +41 (0) 61 926 8989 Switzerland 1104 80 Inquiry
Supplier Advantage
Hangzhou MolCore BioPharmatech Co.,Ltd. 58
Sigma-Aldrich 80
TargetMol Chemicals Inc. 58
Alexis Corporation 74
Nacalai Tesque, Inc. 75
Kanto Chemical Co., Inc. 74
EMD Biosciences, Inc. 66
VWR International 82
Apollo Scientific Ltd. 88
AXXORA, LLC 80

125313-65-7(RO-31-7549)Related Search:

Bisindolylmaleimide V RO 31-7549, IMMOBILIZED RO 31-7549 ACETATE 3,4-Di-1H-indol-3-yl-1H-pyrrole-2,5-dione 3-Isopropenyl-1-methyl-1H-pyrrole
RO-31-7549
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BISINDOLYLMALEIMIDE VIII ACETATE 1H-Pyrrole-2,5-dione, 3-(1-(3-aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)- 3-(1-(3-Aminopropyl)-1H-indol-3-yl)-4-(1-methyl-1H-indol-3-yl)-1H-pyrrole-2,5-dione Bisindolylmaleimide VIII 2-[1-3(AMINOPROPYL)INDOL-3-YL]-3(1-METHYL-1H-INDOL-3-YL)MALEIMIDE, ACETATE RO-31-7549 RO 31-7549 ACETATE SALT BIDINDOLYLMALEIMIDE VIII, ACETETE Ro-31-7549, Monohydrate - CAS 125313-65-7 - Calbiochem 125313-65-7 C24H22N4O2C2H4O2 Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators