GELATINASE A
- CAS No.
- 193807-58-8
- Chemical Name:
- GELATINASE A
- Synonyms
- MMPL;MMP-2;MMP-1;EC 3.4.24.7;EC 3.4.24.3;MMP-2, HUMAN;EC 3.4.24.24;EC: 3.4.24.3;GELATINASE A;COLLAGENASE D
- CBNumber:
- CB1309850
- Molecular Formula:
- C21H19NO4S
- Molecular Weight:
- 381.44
- MOL File:
- 193807-58-8.mol
- Modify Date:
- 2023/9/4 15:51:00
| Melting point | 146-147 °C |
|---|---|
| Boiling point | 595.9±60.0 °C(Predicted) |
| Density | 1.297±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ≤25mM in DMSO |
| pka | 3.26±0.10(Predicted) |
| form | powder |
| color | light brown |
| CAS DataBase Reference | 193807-58-8 |
SAFETY
Risk and Safety Statements
| Hazard Codes | B,Xi |
|---|---|
| Risk Statements | 36/37/38-42 |
| Safety Statements | 23-26-36-24/25 |
| WGK Germany | 2 |
| F | 10-21 |
GELATINASE A price More Price(5)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | SRP3118 | MMP-2 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 193807-58-8 | 10μG | ₹31501.8 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M9445 | Matrix Metalloproteinase-2 from mouse recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution | 193807-58-8 | 10μG | ₹74081.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | M9195 | Matrix Metalloproteinase-1 human recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous solution | 193807-58-8 | 10μG | ₹71972.4 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 444213 | MMP-2, Proenzyme, Human Rheumatoid Synovial Fibroblast | 193807-58-8 | 5μG | ₹24970.01 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | 444208 | MMP-1, Proenzyme, Human Rheumatoid Synovial Fibroblast | 193807-58-8 | 5μG | ₹29730 | 2022-06-14 | Buy |
GELATINASE A Chemical Properties,Uses,Production
Uses
Matrix metalloproteinase-2 (MMP2) human has been used:
- As a standard in zymography to measure gelatinolytic activity of MMP2.
- In enzymatic method for dissociation of brain tissue to single cells.
General Description
Matrix metalloproteinase-2 (MMP-2) also known as gelatinase or type IV collagenase is a 72kDa protein. MMP-2 is a member of matrix metalloproteinase (MMP) family of enzymes. Basic structure of MMP2 contains signal peptide domain that targets the enzyme for secretion, the pro-peptide domain, which is removed when the enzyme is activated and the catalytic site containing gelatin-binding domain.
Biochem/physiol Actions
Matrix Metalloproteinase-2 (MMP-2) cleaves gelatin, type IV, V, VII, X, and XI collagens, fibronectin, elastin, laminin, proteoglycans and a range of non extracellular matrix (ECM ) components. MMP-2 cleaves native type I collagen to N-terminal ? and C-terminal ? fragments identical to those generated by interstitial collagenases. MMP2 and MMP9 play an essential role in matrix degradation and they are implicated in the maintenance of neovascularization. In mice, deletion or inhibition of MMP2 protects against myocardial rupture.
GELATINASE A Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 88)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | China | 888 | 58 | Inquiry |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
| Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
| ABCR GmbH & CO. KG | 49 721 95061 0 | Germany | 6846 | 75 | Inquiry |
| Creative Enzymes | 1-516-855-7709 | United States | 6057 | 58 | Inquiry |
| Alabiochem Tech.Co., Ltd. | 0512-58900862 400-0707518 | China | 997 | 59 | Inquiry |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | China | 11289 | 58 | Inquiry |
| Energy Chemical | 021-58432009 400-005-6266 | China | 44843 | 58 | Inquiry |
193807-58-8(GELATINASE A)Related Search:
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Collagenase Type IV 72 kDa
Gelatinase, 72 kDa
Collagenase Type IV 72 kD
72 Kd Gelatinase 72 Kd Type IV collagenase Gelatinase A
Matrix Metalloproteinase-2 human
PROENZYME MMP-2
PROGELATINASE A
MMP-2
MMP-1 PROENZYME
MMP-1, PROENZYME HUMAN RHEUMATOID SYNOVIAL FIBROBLAST
MMP-1, STABLE HUMAN FIBROBLASTS
MMP-1 ENZYME, HUMAN
MMP-1, HUMAN PROTEIN
MMP-1
MMPL
MMP-2, PROENZYME
MMP-2, PROENZYME HUMAN RHEUMATOID SYNOVIAL FIBROBLAST
MMP-2, PROENZYME MOUSE MACROPHAGE
MMP-2 ENZYME, HUMAN
MMP-2, HUMAN
TYPE IV COLLAGENASE
TYPE 1 COLLAGENASE
72 KDA GELATINASE
72 KDA GELATINASE, PROENZYME
72 KDA TYPE IV COLLAGENASE
72 KDA TYPE IV COLLAGENASE, PROENZYME
72 KD GELATINASE
72 KD TYPE IV COLLAGENASE
ACTIVE MMP-2 ENZYME
MATRIX METALLOPROTEINASE-1
MATRIX METALLOPROTEINASE 1, PROENZYME
MATRIX METALLOPROTEINASE-1, STABLE HUMAN FIBROBLASTS
MATRIX METALLOPROTEINASE 2
MATRIX METALLOPROTEINASE-2 (MOUSE FIBROBLASTS)
MATRIX METALLOPROTEINASE 2, PROENZYME
MATRIX METALLOPROTEINASE, PROENZYME
EC 3.4.24.7
EC 3.4.24.24
EC 3.4.24.3
EC: 3.4.24.3
COLLAGENASE D
COLLAGENASE-1
COLLAGENASE 1 PROENZYME
COLLAGENASE-1, STABLE HUMAN FIBROBLASTS
COLLAGENASE FORM II
COLLAGENASE (GRADE A)
72 kD Gelatinase, 72 kD Type IV Collagenase, Gelatinase A, MMP-2
Matrix Metalloproteinase-2 from mouse fibroblasts
Collagenase-1, Interstitial Collagenase, MMP-1
Matrix Metalloproteinase-1, Stable from human fibroblasts
Matrix Metalloproteinase-2 from human fibroblasts
Matrix Metalloproteinase-2 from mouse
Matrix Metalloproteinase-1 human
Matrix Metalloproteinase-2 from rat fibroblasts
COLLAGENASE (GRADE B)
COLLAGENASE H
COLLAGENASE (72KDA TYPE IV) PROENZYME
COLLAGENASE AND PROTEASE INHIBITOR