GELATINASE A
![GELATINASE A Structure](CAS/20200515/GIF/193807-58-8.gif)
- CAS No.
- 193807-58-8
- Chemical Name:
- GELATINASE A
- Synonyms
- MMPL;MMP-2;MMP-1;EC 3.4.24.7;EC 3.4.24.3;MMP-2, HUMAN;EC 3.4.24.24;EC: 3.4.24.3;GELATINASE A;COLLAGENASE D
- CBNumber:
- CB1309850
- Molecular Formula:
- C21H19NO4S
- Molecular Weight:
- 381.44
- MOL File:
- 193807-58-8.mol
- Modify Date:
- 2023/9/4 15:51:00
Melting point | 146-147 °C |
---|---|
Boiling point | 595.9±60.0 °C(Predicted) |
Density | 1.297±0.06 g/cm3(Predicted) |
storage temp. | 2-8°C |
solubility | ≤25mM in DMSO |
pka | 3.26±0.10(Predicted) |
form | powder |
color | light brown |
CAS DataBase Reference | 193807-58-8 |
SAFETY
Risk and Safety Statements
Hazard Codes | B,Xi |
---|---|
Risk Statements | 36/37/38-42 |
Safety Statements | 23-26-36-24/25 |
WGK Germany | 2 |
F | 10-21 |
GELATINASE A price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | SRP3118 | MMP-2 human recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture | 193807-58-8 | 10μG | ₹31501.8 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M9445 | Matrix Metalloproteinase-2 from mouse recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution | 193807-58-8 | 10μG | ₹74081.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | M9195 | Matrix Metalloproteinase-1 human recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous solution | 193807-58-8 | 10μG | ₹71972.4 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 444213 | MMP-2, Proenzyme, Human Rheumatoid Synovial Fibroblast | 193807-58-8 | 5μG | ₹24970.01 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 444208 | MMP-1, Proenzyme, Human Rheumatoid Synovial Fibroblast | 193807-58-8 | 5μG | ₹29730 | 2022-06-14 | Buy |
GELATINASE A Chemical Properties,Uses,Production
Uses
Matrix metalloproteinase-2 (MMP2) human has been used:
- As a standard in zymography to measure gelatinolytic activity of MMP2.
- In enzymatic method for dissociation of brain tissue to single cells.
General Description
Matrix metalloproteinase-2 (MMP-2) also known as gelatinase or type IV collagenase is a 72kDa protein. MMP-2 is a member of matrix metalloproteinase (MMP) family of enzymes. Basic structure of MMP2 contains signal peptide domain that targets the enzyme for secretion, the pro-peptide domain, which is removed when the enzyme is activated and the catalytic site containing gelatin-binding domain.
Biochem/physiol Actions
Matrix Metalloproteinase-2 (MMP-2) cleaves gelatin, type IV, V, VII, X, and XI collagens, fibronectin, elastin, laminin, proteoglycans and a range of non extracellular matrix (ECM ) components. MMP-2 cleaves native type I collagen to N-terminal ? and C-terminal ? fragments identical to those generated by interstitial collagenases. MMP2 and MMP9 play an essential role in matrix degradation and they are implicated in the maintenance of neovascularization. In mice, deletion or inhibition of MMP2 protects against myocardial rupture.
GELATINASE A Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | China | 888 | 58 | Inquiry |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | China | 32836 | 60 | Inquiry |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | China | 24200 | 58 | Inquiry |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | China | 19915 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
ABCR GmbH & CO. KG | 49 721 95061 0 | Germany | 6846 | 75 | Inquiry |
Creative Enzymes | 1-516-855-7709 | United States | 6057 | 58 | Inquiry |
Alabiochem Tech.Co., Ltd. | 0512-58900862 400-0707518 | China | 997 | 59 | Inquiry |
ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | China | 11289 | 58 | Inquiry |
Energy Chemical | 021-58432009 400-005-6266 | China | 44843 | 58 | Inquiry |
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