Collagenase
![Collagenase Structure](CAS/20180906/GIF/9001-12-1.gif)
- CAS No.
- 9001-12-1
- Chemical Name:
- Collagenase
- Synonyms
- FIBROBLAST;Collagenase IV;Collagenase clostridium histolyticum;Santyl;INTERSTITIAL;Collagenase A;Collagenase II;COLLAGENASE TYPE XI;COLLAGENASE TYPE VII HIGH PURITY;CLGN
- CBNumber:
- CB2112176
- Molecular Formula:
- C60H100N2
- Molecular Weight:
- 849.4494
- MOL File:
- 9001-12-1.mol
- Modify Date:
- 2024/5/18 8:51:54
storage temp. | -20°C |
---|---|
solubility | Soluble in aqueous buffers. |
form | powder |
color | light brown |
PH | 7.0 |
Merck | 2481 |
InChIKey | YRQNKMKHABXEJZ-UVQQGXFZSA-N |
CAS DataBase Reference | 9001-12-1 |
EPA Substance Registry System | Collagenase (9001-12-1) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() ![]() GHS07,GHS08 |
---|---|
Signal word | Danger |
Hazard statements | H315-H319-H334-H335 |
Precautionary statements | P261-P264-P280-P284-P304+P340+P312-P342+P311 |
Hazard Codes | Xn |
Risk Statements | 36/37/38-42 |
Safety Statements | 22-24-26-36/37 |
WGK Germany | 1 |
F | 10-21 |
HS Code | 3507907000 |
Collagenase price More Price(79)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | V900893 | Collagenase from Clostridium histolyticum Type IV, Vetec?, reagent grade, powder, ≥160?CDU/mg solid | 9001-12-1 | 100MG | ₹4018.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | V900893 | Collagenase from Clostridium histolyticum Type IV, Vetec?, reagent grade, powder, ≥160?CDU/mg solid | 9001-12-1 | 1G | ₹20712.6 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | V900892 | Collagenase from Clostridium histolyticum Type II, Vetec?, reagent grade, powder, ≥125?CDU/mg solid | 9001-12-1 | 100MG | ₹4018.2 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | C9891 | Collagenase from Clostridium histolyticum Type IA, 0.5-5.0?FALGPA units/mg solid, ≥125?CDU/mg solid, For general use | 9001-12-1 | 25MG | ₹6182.7 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | V900892 | Collagenase from Clostridium histolyticum Type II, Vetec?, reagent grade, powder, ≥125?CDU/mg solid | 9001-12-1 | 1G | ₹20712.6 | 2022-06-14 | Buy |
Collagenase Chemical Properties,Uses,Production
Uses
This collagenase has been tested with cell lines to verify the product is not cytotoxic. Collagenase is typically used to digest the connective components in tissue samples to liberate individual cells. The concentration for cartilage dispersal is 1-2 mg/ml, but literature searches should be performed for species specific and/or tissue specific concentrations.
Definition
A rare proteinase that catalyzes the hydrolysis of collagen. Collagenase activity has been demonstrated in several venoms of crotalid and viperid snakes and it occurs in certain species of clostridium.
General Description
Collagenase from Clostridium histolyticum comprises of collagenases G and H. Collagenase has N-terminal activator domain and C-terminal peptidase domain. The collagen binding domains (CBD) and polycystic kidney disease-like (PKD-like) domain resides in the peptidase domain. The collagenase module undergoes structural changes upon calcium binding.
Purification Methods
Collagenase is purified by using N-ethylmaleimide to activate the enzyme, and wheat germ agglutinin-agarose affinity chromatography [Callaway et al. Biochemistry 25 4757 1986].
Collagenase Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Nitta Gelatin India Limited | 0484 2864400 | New Delhi, India | 3 | 58 | Inquiry |
K.D.Chem Pharma | 08048619612 | Ahmedabad, India | 5 | 58 | Inquiry |
Vcare Medicines | 08046035803 | Mumbai, India | 114 | 58 | Inquiry |
Choco Inc. | 08068970197Ext 812 | Delhi, India | 1 | 58 | Inquiry |
Kshipra Biotech Private Limited | +91 9754442044 | Madhya Pradesh, India | 32 | 58 | Inquiry |
Aladdin Scientific | +1-+1(833)-552-7181 | United States | 52927 | 58 | Inquiry |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | China | 12456 | 58 | Inquiry |
Hebei Yanxi Chemical Co., Ltd. | +86-17531190177; +8617531190177 | China | 5907 | 58 | Inquiry |
Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618740459177 | China | 1142 | 58 | Inquiry |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | China | 21669 | 55 | Inquiry |