Pepsin
- CAS No.
- 9001-75-6
- Chemical Name:
- Pepsin
- Synonyms
- PEPSIN 1:3000;Pepsine;Pepsin A;BOVINEPEPSINB;BOVINEPEPSINA;IMMOBILIZED PEPSIN;PEPSIN CRYSTALLINE;pepsin from porcine gastric mucosa;Pepsin;Pepsase
- CBNumber:
- CB3134128
- Molecular Formula:
- n.a.
- Molecular Weight:
- 0
- MOL File:
- Mol file
- Modify Date:
- 2024/4/28 15:15:04
| alpha | D26 -64.5° (water pH 4.6) |
|---|---|
| Density | 1.287 g/cm3 |
| storage temp. | -20°C |
| solubility | 10 mM HCl: soluble1.0mg/mL, clear to faintly turbid, colorless |
| form | powder |
| color | slightly beige |
| Odor | Odorless |
| Water Solubility | Soluble in water and dilute aqueous buffers |
| Sensitive | Hygroscopic |
| Merck | 13,7225 |
| Stability | Stable. Incompatible with strong bases, alkalies, metallic salts, alcohols. |
| CAS DataBase Reference | 9001-75-6 |
| EPA Substance Registry System | Pepsin A (9001-75-6) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS08 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H334 | |||||||||
| Precautionary statements | P261-P284-P304+P340-P342+P311-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 36/37/38-42-42/43 | |||||||||
| Safety Statements | 22-24-26-36/37-36-45 | |||||||||
| WGK Germany | 1 | |||||||||
| RTECS | SC6132000 | |||||||||
| F | 3-10 | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 35079090 | |||||||||
| NFPA 704 |
|
Pepsin price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich(India) | V900497 | Pepsin from porcine gastric mucosa Vetec?, reagent grade | 9001-75-6 | 100G | ₹6870.9 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | V900497 | Pepsin from porcine gastric mucosa Vetec?, reagent grade | 9001-75-6 | 500G | ₹26562.3 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SRE0001 | Pepsin from porcine gastric mucosa Suitable for manufacturing of diagnostic kits and reagents, lyophilized powder, ≥3200?units/mg protein | 9001-75-6 | 5G | ₹66766.5 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SRE0001 | Pepsin from porcine gastric mucosa Suitable for manufacturing of diagnostic kits and reagents, lyophilized powder, ≥3200?units/mg protein | 9001-75-6 | 10G | ₹115573.2 | 2022-06-14 | Buy |
| Sigma-Aldrich(India) | SRE0001 | Pepsin from porcine gastric mucosa Suitable for manufacturing of diagnostic kits and reagents, lyophilized powder, ≥3200?units/mg protein | 9001-75-6 | 100G | ₹936673.5 | 2022-06-14 | Buy |
Pepsin Chemical Properties,Uses,Production
Chemical Properties
Pepsin is a white or pale yellow powder extracted from the gastric mucosa of pigs, sheep or cattle. Soluble in water, the aqueous solution is acidic. Isoelectric point pH=1. Insoluble in ethanol, chloroform, ether. It is non-toxic and has a special smell of meat; it is hygroscopic. The dry enzyme is relatively stable and will not be inactivated when heated to 1000C for 10min. Its aqueous solution is heated to above 700C or above pH6.2 and begins to inactivate, and when pH>8, it is irreversibly inactivated. It is relatively stable in strong acid solution, and the optimum pH is 1.5-2. Its digestibility is strongest when it contains 0.2% to 0.4% hydrochloric acid (pH 1.6 to 1.8), so it is often used in combination with dilute hydrochloric acid.
Uses
Pepsin is an enzyme that is secreted in the digestive track of mammals. It works to break down proteins into smaller peptides which can readily be absorbed by the small intestine.
Definition
pepsin is an enzyme that catalysesthe breakdown of proteins topolypeptides in the vertebrate stomach.It is secreted as an inactive precursor,pepsinogen.
Preparation
Pepsin is a stomach enzyme that serves to digest proteins found in ingested food. Production method of pepsin: using porcine gastric mucosa as raw material, after extraction with phosphate buffer solution, use DEAE-cellulose column chromatography, and after acidification, use Sephadex C-25 and Sephadex G-25 column chromatography again to refine the product.
General Description
Pepsin powder is prepared from the gastric mucosa of pigs, cattle or sheep.
Purification Methods
Pepsin is re-chromatographed on a column of Amberlite CG-50 using a pH gradient prior to use. Crystallise it from EtOH. [Richmond et al. Biochim Biophys Acta 29 453 1958, Huang & Tang, J Biol Chem 244 1085 1969, 245 2189 1970.]
Pepsin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| Anthem Biosciences Pvt Ltd | +91-8066724000 +91-9900044575 | Karnataka, India | 38 | 58 | Inquiry |
| Meteoric Biopharmaceuticals Pvt. Ltd. | +91-8511121361 +91-8511121361 | Mumbai, India | 71 | 58 | Inquiry |
| Excellent Biotechnologies | +91-8904857846 +91-8032550712 | Karnataka, India | 14 | 58 | Inquiry |
| Enzyme BioScience pvt Ltd | +91-9722913685 +91-8690076795 | Gujarat, India | 25 | 58 | Inquiry |
| Apollo ingredients Pvt Ltd | +91-7219888886 | Maharashtra, India | 31 | 58 | Inquiry |
| Ann Organic India Private Limited | +91-8445757524 +91-8445757524 | Uttar Pradesh, India | 6 | 58 | Inquiry |
| Symbio Generrics (I) Pvt Ltd | +91-8121318328 +91-9099033709 | Karnataka, India | 22 | 58 | Inquiry |
| Beloorbayir Biotech Ltd | +91-8792661159 +91-8867683718 | Karnataka, India | 25 | 58 | Inquiry |
| Merck Ltd | +91-2262109800 +91-2262109000 | Maharashtra, India | 272 | 58 | Inquiry |
| Fido Pharma | +91-9876274767 +91-9167231289 | Haryana, India | 23 | 58 | Inquiry |
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