AC-IETD-AFC

CAS No.: 211990-57-7

Chemical Name:: AC-IETD-AFC

Synonyms: AC-IETD-AFC;AC-ILE-GLU-THR-ASP-AFC;Caspase 8 Substrate 1f;CGUOWXRXLQXOKO-FCQBACSVSA-N;M.W. 729.66 C31H38F3N5O12;CASPASE-8 FLUOROGENIC SUBSTRATE;CASPASE 8 SUBSTRATE 1F, FLUOROGENIC;GRANZYME B SUBSTRATE I, COLORIMETRIC;AC-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN;N-ACETYL-ILE-GLU-THR-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN)

CBNumber:: CB1395556

Molecular Formula:: C31H38F3N5O12

Molecular Weight:: 729.65

MOL File:: 211990-57-7.mol

Modify Date:: 2024/7/2 8:55:00

Request For Quotation

AC-IETD-AFC Properties

Boiling point	1113.8±65.0 °C(Predicted)
Density	1.437±0.06 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO
pka	4.09±0.10(Predicted)
form	Lyophilized powder
color	White to off-white

AC-IETD-AFC Chemical Properties,Uses,Production

Uses

N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-(trifluoromethyl)coumarin is a fluorogenic substrate for caspases -6, -8, and -10. The IETD sequence is based on the procaspase-3 cleavage site. Residues 172-175 of procaspase-3 are cleaved during apoptosis to produce the p12 subunit and a p20 peptide that is further cleaved to form the p17 subunit of mature caspase 3.

AC-IETD-AFC Preparation Products And Raw materials

Raw materials

Preparation Products

AC-IETD-AFC Suppliers

Global( 75)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
career henan chemical co	+86-0371-86658258 +8613203830695	China	29826	58	Inquiry
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	China	10522	58	Inquiry
DONBOO AMINO ACID COMPANY	+8613063595538	China	9365	58	Inquiry
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd	18014456767 18014456767	China	1349	58	Inquiry
Nanjing Yuanpeptide Biotech Co.，Ltd.	18168071971	China	2977	58	Inquiry
Nanjing Yushengkang Biotechnology Co., Ltd	13327808530	China	2179	58	Inquiry
Guangzhou Younan Technology Co., Ltd	020-020-82000279 18988968278	China	2493	58	Inquiry
Hangzhou Beiputai Biopharmaceutical Co., Ltd	0571-85350119 13305819357	China	3793	58	Inquiry
Shanghai Maclean Biochemical Technology Co., LTD	021-50706066 15221275939	China	29803	58	Inquiry
Wuxi Helen Biotechnology Co., Ltd.,	0510-85629785 18013409632	China	14092	58	Inquiry

Supplier	Advantage
career henan chemical co	58
Zhejiang J&C Biological Technology Co.,Limited	58
DONBOO AMINO ACID COMPANY	58
Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd	58
Nanjing Yuanpeptide Biotech Co.，Ltd.	58
Nanjing Yushengkang Biotechnology Co., Ltd	58
Guangzhou Younan Technology Co., Ltd	58
Hangzhou Beiputai Biopharmaceutical Co., Ltd	58
Shanghai Maclean Biochemical Technology Co., LTD	58
Wuxi Helen Biotechnology Co., Ltd.,	58

211990-57-7(AC-IETD-AFC)Related Search:

GRANZYME B AC-IETD-CHO AC-IETD-AFC

CASPASE 8 SUBSTRATE 1F, FLUOROGENIC CASPASE-8 FLUOROGENIC SUBSTRATE GRANZYME B SUBSTRATE I, COLORIMETRIC AC-IETD-AFC AC-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUORO-METHYLCOUMARIN AC-ILE-GLU-THR-ASP-AFC N-ACETYL-ILE-GLU-THR-ASP-(7-AMINO-4-TRIFLUOROMETHYLCOUMARIN) N-ACETYL-ILE-GLU-THR-ASP-7-AMINO-4-TRIFLUOROMETHYLCOUMARIN AFC M.W. 729.66 C31H38F3N5O12 N-Acetyl-L-isoleucyl-L-alpha-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-alpha-asparagine CGUOWXRXLQXOKO-FCQBACSVSA-N Caspase 8 Substrate 1f L-α-Asparagine, N-acetyl-L-isoleucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]- Ac-IETD-AFC (N-Acetyl-Ile-Glu-Thr-Asp-7-amino-4-Trifluoromethylcoumarin) 211990-57-7 Caspase/Related Products peptide Caspases/Apoptosis