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Scopine

Scopine Structure
CAS No.
498-45-3
Chemical Name:
Scopine
Synonyms
SCOPINE;Scopine>SCOPINE, 97+%;6,7-Epoxytropine;Scopine USP/EP/BP;Scopine (6CI, 7CI);Atropine Impurity 2;Scopolamine alcohol;(2R,4S,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol;(1α,2β,4β,5α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7β-ol
CBNumber:
CB1397398
Molecular Formula:
C8H13NO2
Molecular Weight:
155.2
MOL File:
498-45-3.mol
MSDS File:
SDS
Modify Date:
2024/6/11 19:18:13

Scopine Properties

Melting point 73.0 to 77.0 °C
Boiling point 281.3±40.0 °C(Predicted)
Density 1.284±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Dichloromethane; Methanol
pka 14?+-.0.20(Predicted)
form Solid
color White
InChIKey FIMXSEMBHGTNKT-RZVDLVGDSA-N
CAS DataBase Reference 498-45-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

HS Code  29349990

Scopine Chemical Properties,Uses,Production

Chemical Properties

White to white crystal powder

Uses

Scopin is an Intermediate in the synthesis of Scopine Methobromide (Tiotropium EP Impurity G) (S199985), an impurity of Tiotropium (T444850), an muscarinic receptor antagonist and bronchodilator.

Scopine Preparation Products And Raw materials

Raw materials

Preparation Products

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SCOPINE (1alpha,2beta,4beta,5alpha,7beta)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02.4]nonan-7-ol SCOPINE, 97+% (1α,2β,4β,5α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7β-ol (1β,2α,4α,5β,7α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol (1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol 3-Oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol,9-Methyl-, (1a,2b,4b,5a,7b)- Atropine Impurity 2 Scopine> 6,7-Epoxytropine 3-Oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol, 9-methyl-, (1α,2β,4β,5α,7β)- (2R,4S,7s)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol Scopine USP/EP/BP rel-(1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7-ol (1α,2β,4β,5α)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.02,4]nonan-7β-ol Scopine (6CI, 7CI) Scopolamine alcohol 498-45-3 API intermediates Tiotropium Bromide Intermediates Inhibitors 498-45-3