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2-Amino-2-phenylacetic acid

2-Amino-2-phenylacetic acid Structure
CAS No.
2835-06-5
Chemical Name:
2-Amino-2-phenylacetic acid
Synonyms
2-Phenylglycine;α-phenylglycine;DL-ALPHA-PHENYLGLYCINE;H-DL-PHG-OH;DL-PHENYLGLYCINE;DL-2-PHENYLGLYCINE;DL-α-Phenylglycine;2-Amino-2-phenyL;DL-A-PHENYLGLYCINE;RARECHEM AK ML 0501
CBNumber:
CB1420201
Molecular Formula:
C8H9NO2
Molecular Weight:
151.17
MOL File:
2835-06-5.mol
MSDS File:
SDS
Modify Date:
2023/8/15 17:37:19

2-Amino-2-phenylacetic acid Properties

Melting point 290 °C (subl.)(lit.)
alpha [α]D20-0.5~+0.5゜ (c=5, dil. HCl)
Boiling point 273.17°C (rough estimate)
Density 1.2023 (rough estimate)
refractive index 1.5810 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
solubility almost transparency in Sodium hydroxide solution
pka 1.94±0.10(Predicted)
form Crystalline Powder
color White to off-white
Water Solubility 115g/L(100 ºC)
Merck 14,7291
BRN 3197862
InChIKey ZGUNAGUHMKGQNY-UHFFFAOYSA-N
CAS DataBase Reference 2835-06-5(CAS DataBase Reference)
NIST Chemistry Reference Benzeneacetic acid, «alpha»-amino-, (.+/-.)-(2835-06-5)
EPA Substance Registry System 2-Phenylglycine (2835-06-5)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  F,C
Risk Statements  11-34
Safety Statements  24/25-45-36/37/39-26-16
WGK Germany  3
TSCA  Yes
HS Code  29224999
NFPA 704
1
2 0

2-Amino-2-phenylacetic acid price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) P25507 2-Phenylglycine 95% 2835-06-5 100G ₹4622.28 2022-06-14 Buy
TCI Chemicals (India) P0326 DL-2-Phenylglycine 2835-06-5 25G ₹1600 2022-05-26 Buy
TCI Chemicals (India) P0326 DL-2-Phenylglycine 2835-06-5 500G ₹10200 2022-05-26 Buy
ottokemi P 1668 DL-Phenyl glycine , GR 99%+ 2835-06-5 25gm ₹1908 2022-05-26 Buy
ottokemi P 1668 DL-Phenyl glycine , GR 99%+ 2835-06-5 100gm ₹4302 2022-05-26 Buy
Product number Packaging Price Buy
P25507 100G ₹4622.28 Buy
P0326 25G ₹1600 Buy
P0326 500G ₹10200 Buy
P 1668 25gm ₹1908 Buy
P 1668 100gm ₹4302 Buy

2-Amino-2-phenylacetic acid Chemical Properties,Uses,Production

Description

2-Amino-2-phenylacetic acid is a natural compound that has been identified as a selective inhibitor of cyclooxygenase 2 (COX-2), and it exhibits antiinflammatory activity. It has been shown to inhibit COX-2 at low concentrations and to be less potent than aspirin in inhibiting COX-1. It is also an amide, with a molecular weight of 296. In order to determine the structure of it, XRD data was collected from the monosodium salt form of the compound. The ester hydrochloride form was used for enzyme activity assays because it is more soluble in water than the free base form. The synthesis of 2-Amino-2-phenylacetic acid was achieved through a two step process involving amide formation and hydrolysis.

Chemical Properties

white amorphous powder

Uses

DL-α-Phenylglycine is used as a reagent in the synthesis of benzoquinone-amino acid conjugates which have antibacterial activity.

Definition

ChEBI: An amino acid with a structure in which a phenyl ring is bonded to the alpha-carbon of glycine.

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RARECHEM AK ML 0501 (.+/-.)-alpha-Phenylglycine (+/-)-benzeneaceticaci .alpha.-amino-,(+-)-Benzeneaceticacid -Aminobenzeneaceticacid Benzeneacetic acid, alpha-amino-, (± Benzeneaceticacid,-amino-,(+-)- PHENYLGLYCINE(D,L-) DL-A-AMINOPHENYLACETIC ACID CRYSTALLINE Benzeneacetic acid, alpha-amino- (9CI) Benzeneacetic acid, .alpha.-amino- (n)-à-aminophenylacetic acid 2-Amino-2-phenylacetic acid DL-a-Aminophenylglycine acid (±)-α-Aminophenylacetic acid, DL-α-Phenylglycine DL-α-Aminophenylacetic acid 2-Phenyl-DL-glycine rac-(R*)-Aminophenylacetic acid DL-alpha-Phenylglycine,99% DL-2-Phenylglycine (±)-α-Aminophenylacetic acid 2-Phenylglycine,(±)-α-Aminophenylacetic acid, DL-α-Phenylglycine DL-alpha-Phenylglycine, 99% 100GR (-)-1-phenylglycine DL-A-AMINOPHENYLACETIC ACID FOR SYNTHESI Benzeneaceticacid,a-aMino- Glycine, 2-phenyl-, DL- AMINO-PHENYL-ACETIC ACID (+/-)-ALPHA-AMINOPHENYLACETIC ACID 2-Phenylglycine 95% DL-A-AMINOPHENYLACETIC ACID DL-2-AMINOPHENYLACETIC ACID DL-A-PHENYLGLYCINE DL-ALPHA-PHENYLAMINOACETIC ACID DL-ALPHA-AMINOPHENYLACETIC ACID LABOTEST-BB LT00005726 H-DL-(PHENYL)GLY-OH Mezlocillin Impurity 6 2-Amino-2-phenyL Clopidogrel Impurity 28 DL-α-Phenylg151.16 lycine DL-2-Phenylglycine> 2-Amino-2-phenylacetic acid USP/EP/BP Chemical Reagent Bloom Tech 2-Amino-2-Phenylacetic Acid CAS?2835-06-5 DL-Phenyl glycine, GR 99%+ 2-Phenylglycine DL-2-PHENYLGLYCINE DL-ALPHA-PHENYLGLYCINE DL-PHENYLGLYCINE H-DL-PHG-OH α-phenylglycine DL-α-Phenylglycine 2-Phenylglycine,lactation,Endogenous Metabolite,inhibit,2Phenylglycine,breast,period,milk,Inhibitor,2 Phenylglycine Benzeneacetic acid, α-amino- (+/-)-Alpha-AMinophenylacetic Acid 2835-06-5 835-06-5 2383-06-5 2835-06-05