Sulfanilic acid
- CAS No.
- 121-57-3
- Chemical Name:
- Sulfanilic acid
- Synonyms
- SULPHANILIC ACID;4-AMINOBENZENESULFONIC ACID;sulfanilic;P-AMINOBENZENESULFONIC ACID;4-aminobenzenesulfonate;SULFANILLIC ACID;Sulphanillic Acid;ANILINE-4-SULFONIC ACID;SULFANILIC ACID ANHYD PWD;4-AMINOBENZENESULPHONIC ACID
- CBNumber:
- CB1489237
- Molecular Formula:
- C6H7NO3S
- Molecular Weight:
- 173.19
- MOL File:
- 121-57-3.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/12/18 14:07:02
Melting point | >300 °C(lit.) |
---|---|
Boiling point | 288 ℃ |
Density | 1.485 |
vapor pressure | 0Pa at 25℃ |
refractive index | 1.5500 (estimate) |
storage temp. | Store below +30°C. |
solubility | 10g/l |
pka | 3.24(at 25℃) |
form | solid |
color | White to Off-White |
PH | 2.5 (10g/l, H2O, 20℃) |
Water Solubility | 0.1 g/100 mL (20 ºC) |
Merck | 14,8926 |
BRN | 908765 |
Stability | Stable. Incompatible with strong oxidizing agents. |
InChIKey | HVBSAKJJOYLTQU-UHFFFAOYSA-N |
LogP | -2.3 at 25℃ |
CAS DataBase Reference | 121-57-3(CAS DataBase Reference) |
NIST Chemistry Reference | Benzenesulfonic acid, 4-amino-(121-57-3) |
EPA Substance Registry System | Sulfanilic acid (121-57-3) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H317-H319 | |||||||||
Precautionary statements | P261-P264-P272-P280-P302+P352-P305+P351+P338 | |||||||||
Hazard Codes | C,Xi | |||||||||
Risk Statements | 36/38-43-34 | |||||||||
Safety Statements | 26-36/37/39-45-37-24-36/37 | |||||||||
RIDADR | UN 2790 8/PG 3 | |||||||||
WGK Germany | 1 | |||||||||
RTECS | WP3895500 | |||||||||
Autoignition Temperature | >400 °C | |||||||||
TSCA | Yes | |||||||||
HS Code | 29214210 | |||||||||
Hazardous Substances Data | 121-57-3(Hazardous Substances Data) | |||||||||
Toxicity | LD50 orally in Rabbit: 12300 mg/kg | |||||||||
NFPA 704 |
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Sulfanilic acid price More Price(26)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich(India) | 86090 | Sulfanilic acid puriss. p.a., ≥99.0% (T) | 121-57-3 | 5G | ₹3799.58 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 86090 | Sulfanilic acid puriss. p.a., ≥99.0% (T) | 121-57-3 | 100G | ₹5813.03 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | PHR1419 | Sulfanilic Acid Pharmaceutical Secondary Standard; Certified Reference Material | 121-57-3 | 500MG | ₹8281.13 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 86090 | Sulfanilic acid puriss. p.a., ≥99.0% (T) | 121-57-3 | 500G | ₹16497.3 | 2022-06-14 | Buy |
Sigma-Aldrich(India) | 8.22338 | Sulfanilic acid for synthesis | 121-57-3 | 1KG | ₹4280 | 2022-06-14 | Buy |
Sulfanilic acid Chemical Properties,Uses,Production
Description
Sulfanilic acid (4-amino benzene sulfonic acid ) is an off-white crystalline solid which finds application in quantitative analysis of nitrate and nitrite ions. The solid acid exists as a zwitterion, and has an unusually high melting point.
Chemical Properties
greyish-white crystals or powder
Uses
Sulfanilic Acid (Sulfadimethoxine EP Impurity D) is a toxic metabolite of Tartrazine (T007700). Used as Ehrlich’s reagent, for detecting of nitrites. Antibacterial.
Application
As the compound readily form diazo compounds, it is used to make dyes and sulpha drugs . This property is also used for the quantitative analysis of nitrate and nitrite ions by diazonium coupling reaction with N-(1-Naphthyl) ethylene diamine , resulting in an azo dye, and the concentration of nitrate or nitrite ions were deduced from the color intensity of the resulting red solution by colorimetry.
It is also used as a standard in combustion analysis.
Definition
ChEBI: An aminobenzenesulfonic acid that is aniline sulfonated at the para-position.
General Description
White powder with faint purple tinge. Grayish-white flat crystals. Becomes anhydrous at around 212°F. Low toxicity (used medicinally).
Air & Water Reactions
Insoluble in water.
Reactivity Profile
Sulfanilic acid is an amino acid. Reacts weakly with both acids and bases.
Fire Hazard
Flash point data for Sulfanilic acid are not available, however Sulfanilic acid is probably combustible.
Purification Methods
Crystallise the acid (as dihydrate) from boiling water. Dry it at 105o for 2-3hours, then over 90% H2SO4 in a vacuum desiccator. The S-benzylisothiuronium salt has m 187o (from aqueous EtOH). [Beilstein 14 IV 2655.]
Sulfanilic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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