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Tartrazine

Tartrazine Structure
CAS No.
1934-21-0
Chemical Name:
Tartrazine
Synonyms
CI 19140;YELLOW 5;ACID YELLOW 23;E102;LAKE TARTRAZINE;Yellow 100;HYDRAZINE YELLOW;Tartrazine (E102);Tartrazine Yellow 5;Edible Lemon Yellow
CBNumber:
CB2219301
Molecular Formula:
C16H13N4NaO9S2
Molecular Weight:
492.41
MOL File:
1934-21-0.mol
MSDS File:
SDS
Modify Date:
2024/6/21 13:10:12

Tartrazine Properties

Melting point 300 °C
Boiling point 909.54℃[at 101 325 Pa]
Density 2.121[at 20℃]
vapor pressure 0Pa at 25℃
storage temp. room temp
solubility DMSO (Sparingly, Heated), Water (Slightly)
Colour Index 19140
form Powder
color Orange
Water Solubility 260 g/L (30 ºC)
Sensitive Hygroscopic
Merck 14,9072
BRN 69850
Stability Stable. Hygroscopic. Incompatible with strong oxidizing agents.
Biological Applications Treating hepatitis,periodontal disease,psoriasis
LogP -1.572 at 20℃
EPA Substance Registry System Tartrazine (1934-21-0)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08
Signal word  Danger
Hazard statements  H317-H334
Precautionary statements  P261-P272-P280-P284-P302+P352+P333+P313+P363-P304+P340+P342+P311-P501-P280g-P304+P340-P342+P311a-P501a
Hazard Codes  Xn
Risk Statements  42/43
Safety Statements  22-36/37-45-24/25
WGK Germany  1
RTECS  UQ6400000
TSCA  Yes
HS Code  32129000
Toxicity LD50 oral in mouse: 12750mg/kg
NFPA 704
1
1 0

Tartrazine price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) T0388 Tartrazine Dye content ≥85?% 1934-21-0 100G ₹4150 2022-06-14 Buy
Sigma-Aldrich(India) T0388 Tartrazine Dye content ≥85?% 1934-21-0 500G ₹12460 2022-06-14 Buy
Sigma-Aldrich(India) 03322 Tartrazine analytical standard 1934-21-0 25MG ₹3274.5 2022-06-14 Buy
ALFA India ALF-A17682-36 Tartrazine 1934-21-0 500g ₹12028 2022-05-26 Buy
ALFA India ALF-A17682-22 Tartrazine 1934-21-0 100g ₹2792 2022-05-26 Buy
Product number Packaging Price Buy
T0388 100G ₹4150 Buy
T0388 500G ₹12460 Buy
03322 25MG ₹3274.5 Buy
ALF-A17682-36 500g ₹12028 Buy
ALF-A17682-22 100g ₹2792 Buy

Tartrazine Chemical Properties,Uses,Production

Description

FD & C Yellow No. 5 is principally the trisodium salt of 4,5-dihydro-5-oxo-l-(4-sulfophenyl)-4-[4-sulfophenyl-azo]-lH- pyrazole-3-carboxylic acid.
The colorant is a yellow-orange powder that dissolves in water to give a solution golden yellow at neutrality and in acid. When dissolved in concentrated sulfuric acid, it yields an orange-yellow solution that turns yellow when diluted with water.
FD & C Yellow No. 5 is regularly used in desserts (e.g., dessert powders, puddings, custards, gelatin, ice cream), candy, preserves, beverages (including carbonated soda beverages and flavored drink powders), prepared meats, and canned and frozen vegetables. It is also used in pharmaceuticals and cosmetics.1 .

Chemical Properties

Deep yellow powder

Uses

Tartrazine is used as a dye for wool and silks; as colorant in food, drugs, and cosmetics. In biochemistry as an adsorption-elution indicator for chloride estimations. Tartrazine (otherwise known as E number E102, C.I. 19140, or FD&C Yellow 5) is a synthetic lemon yellow azo dye used as a food coloring. Tartrazine appears to cause the most allergic and intolerance reactions of all the azo dyes, particularly among as thmatics and those with an aspirin intolerance.

Preparation

Commonly known??Tartmzine ?. (a) 4-Aminobenzenesulfonic acid diazo, and 5-Oxo-1-(4-sulfophenyl)-4,5-dihydro-1H-pyrazole-3-carboxylic acid coupled; (b) 2 Moore 4-Aminobenzenesulfonic acid?and dioxide 5 diacid reaction

Definition

ChEBI: An organic sodium salt which is the trisodium salt of tartrazine acid. A synthetic lemon yellow azo dye used as a food colouring.

World Health Organization (WHO)

Tartrazine is widely used as a permitted colouring agent in food and pharmaceutical preparations. Its use has been associated with allergic reactions some of which have been severe. Several national drug regulatory authorities now require a warning on labels of products containing tartrazine and some manufacturers have voluntarily withdrawn this compound from their products.

General Description

Tartrazine is a synthetic azo dye, commonly found in drugs, food products and cosmetics. It can be synthesized by the reaction of sulfanilic acid with 3-carboxy-l-(4-sulfophenyl)-5-pyrazolone.

Hazard

An allergen.

Toxicology

This coloring agent is 5-hydroxy-1-p-sulfophenyl-4-(p-sulfophenylazo)- pyrazol-3-carboxylic acid, trisodium salt. It is a yellow powder and has been used as food coloring additive since 1916. Tartrazine is known as the least toxic coloring agent among synthetic coloring chemicals. The median acute oral lethal dose of tartrazine in mice is 12.17 g/kg. Beagle dogs received tartrazine as 2% of the diet for two years without adverse effects, with the possible exception of pyloric gastritis in one dog. Tumor incidence was unchanged relative to controls, in rats receiving tartrazine at 1.5% of the diet for 64 weeks, and in rats administered this dye at 5.0% of the diet for two years.
Human sensitivity to tartrazine has been reported with some frequency and has been estimated to occur in 1/10,000 persons. Anaphylactic shock, potentially life-threatening, has been reported but symptoms more commonly cited are urticaria (hives), asthma, and purpura (blue or purple spots on the skin or mucous membrane).

Safety Profile

Low toxicity by ingestion. Mutation data reported. When heated to decomposition it emits very toxic fumes of NOx, SOx, and Na2O.

Global( 676)Suppliers
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