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Sodium Phosphate, Dibasic

Sodium Phosphate, Dibasic Structure
CAS No.
7558-79-4
Chemical Name:
Sodium Phosphate, Dibasic
Synonyms
DISODIUM PHOSPHATE;DSP;DISODIUM HYDROGEN PHOSPHATE;DIBASIC SODIUM PHOSPHATE;DSPA;DISODIUM PHOSPHATE DIHYDRATE;BUFFER SOLUTION;Sodium phosphate dibasic anhydrous;SODIUM HYDROGENPHOSPHATE;SODIUM MONOHYDROGEN PHOSPHATE
CBNumber:
CB1242667
Molecular Formula:
Na2HPO4
Molecular Weight:
141.96
MOL File:
7558-79-4.mol
MSDS File:
SDS
Modify Date:
2024/8/6 17:20:39

Sodium Phosphate, Dibasic Properties

Melting point 243-245 °C
Density 1.064 g/mL at 20 °C
vapor density 4.9 (vs air)
vapor pressure 0Pa at 20℃
FEMA 2398 | DISODIUM PHOSPHATE
storage temp. Store at +5°C to +30°C.
solubility H2O: 0.5 M at 20 °C, clear, colorless
form powder
color White
PH 8.9-9.2 (25℃, 50g/L in water)
pka (1) 2.15, (2) 6.82, (3) 12.38 (at 25℃)
Odor odorless
Water Solubility >=10 g/100 mL at 20 ºC
Sensitive Hygroscopic
λmax λ: 260 nm Amax: 0.019
λ: 280 nm Amax: 0.016
Merck 14,8659
Stability Stable. Incompatible with strong acids. Hygroscopic.
InChIKey BNIILDVGGAEEIG-UHFFFAOYSA-L
LogP -2.15
CAS DataBase Reference 7558-79-4(CAS DataBase Reference)
EPA Substance Registry System Disodium phosphate (7558-79-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25
RIDADR  UN 3077 9 / PGIII
WGK Germany  3
RTECS  WC4500000
3
TSCA  Yes
HS Code  28352200
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
NFPA 704
0
1 1

Sodium Phosphate, Dibasic price More Price(81)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) S9763 Sodium phosphate dibasic ACS reagent, ≥99.0% 7558-79-4 100G ₹4763 2022-06-14 Buy
Sigma-Aldrich(India) S9763 Sodium phosphate dibasic ACS reagent, ≥99.0% 7558-79-4 500G ₹10132.2 2022-06-14 Buy
Sigma-Aldrich(India) S9763 Sodium phosphate dibasic ACS reagent, ≥99.0% 7558-79-4 1KG ₹20599.98 2022-06-14 Buy
Sigma-Aldrich(India) S9763 Sodium phosphate dibasic ACS reagent, ≥99.0% 7558-79-4 2.5KG ₹26477.95 2022-06-14 Buy
Sigma-Aldrich(India) S9763 Sodium phosphate dibasic ACS reagent, ≥99.0% 7558-79-4 12KG ₹40626.23 2022-06-14 Buy
Product number Packaging Price Buy
S9763 100G ₹4763 Buy
S9763 500G ₹10132.2 Buy
S9763 1KG ₹20599.98 Buy
S9763 2.5KG ₹26477.95 Buy
S9763 12KG ₹40626.23 Buy

Sodium Phosphate, Dibasic Chemical Properties,Uses,Production

Description

Sodium phosphate dibasic is highly hygroscopic and water soluble. Useful in conjunction with Sodium Phosphate, Monobasic in the preparation of biological buffers. It is commonly used in biological assay buffers. Sodium is required for nerve and muscle functioning. Sodium Phosphate Dibasic can be used as a dietary supplement and as a nutrient. Sodium hydrogen phosphate is used in food and water treatment in conjunction with trisodium phosphate.In foods, it is used to adjust pH. In water treatment, It retards calcium scale formation. It is also found in some detergents and cleaning agents. This product is known to be Used in many applications including the purification of antibodies. It is used as a saline laxative to treat constipation or to clean the bowel before a colonoscopy.

Chemical Properties

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water; 874 SODIUM PHOSPHATE, DIBASIC insoluble in alcohol. The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C. The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C. The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C. All the hydrates are soluble in water and insoluble in alcohol.

Physical properties

The anhydrous compound is white crystalline powder; hygroscopic; density 1.70 g/cm3; converts to sodium pyrophosphate at 240°C; soluble in water;insoluble in alcohol.
The dihydrate is a crystalline powder or granular solid; density 2.066 g/cm3 at 15°C; loses water of crystallization at 92.5°C.
The heptahydrate is a powdered or granular crystalline solid; density 1.679 g/cm3; loses five molecules of water at 48°C.
The dodecahydrate is made up of translucent crystals or granules; density 1.524 g/cm3; readily loses five water molecules on exposure to air at ambient temperature; melts at 35°C when the salt contains all water of crystallization; loses all water at 100°C.
All the hydrates are soluble in water and insoluble in alcohol.

Occurrence

Disodium phosphate is anhydrous or contains two molecules of water of hydration

Uses

Sodium Phosphate, Dibasic is used as a laboratory reagent and a buffer in chemical analysis. Other uses are in manufacturing ceramics, detergents, and enamels; as a mordant in dyeing; for fireproofing paper and wood; for weighting and printing silk; in the treatment of boiler water; as a sequestrant in food; as a dietary supplement; in soldering enamels; and in fertilizers. It is used therapeutically as a cathartic.

Preparation

Dibasic sodium phosphate is prepared by treating phosphoric acid with a slight excess of sodium carbonate. The solution is boiled to expel carbon dioxide. Upon cooling dodecahydrate crystallizes out. Heating dodecahydrate at 100°C forms the anhydrous salt.
H3PO4 + Na2CO3 → Na2HPO4 + CO2 + H2O
Dibasic sodium phosphate also is prepared by reacting dibasic calcium phosphate with sodium carbonate. The product calcium carbonate precipitates leaving dibasic sodium salt in the solution. The solution on cooling yields crystals of hydrated product.
CaHPO4 + Na2CO3 → CaCO3 + Na2HPO4

General Description

Sodium phosphate dibasic in combination with sodium phosphate monobasic is used in the preparation of oral sodium phosphate solution (OSPS), which is a purgative used for bowel cleansing before colonoscopy.

Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal, subcutaneous, and intramuscular routes. Mildly toxic by ingestion. A skin and eye irritant. When heated to decomposition it emits toxic fumes of POx and Na2O. See also PHOSPHATES.

Purification Methods

Crystallise the salt twice from warm water, by cooling. Dry in air, then in an oven overnight at 130o. It should be dried before use as it is slightly hygroscopic. It forms di-, hepta-and deca-hydrates.

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