1-Adamantanemethanol
- CAS No.
- 770-71-8
- Chemical Name:
- 1-Adamantanemethanol
- Synonyms
- AKOS BC-0668;1-amantadinol;Adamantanemethanol;1-Adamantlcarbinol;1-adamantanemethol;RARECHEM AQ TC 1004;CHEMBRDG-BB 4013930;1-ADAMANTYLMETHANOL;1-Adamantylcarbinol;1-ADAMANTANEMETHANOL
- CBNumber:
- CB1448137
- Molecular Formula:
- C11H18O
- Molecular Weight:
- 166.26
- MOL File:
- 770-71-8.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/8/21 22:41:43
| Melting point | 114-117 °C (lit.) |
|---|---|
| Boiling point | 234.5°C (rough estimate) |
| Density | 0.8802 (rough estimate) |
| refractive index | 1.5000 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| pka | 15.51±0.10(Predicted) |
| form | Crystalline Powder |
| color | White |
| Water Solubility | Insoluble in water. Solubility in methanol (almost transparency). |
| BRN | 1853339 |
| InChI | InChI=1S/C11H18O/c12-7-11-4-8-1-9(5-11)3-10(2-8)6-11/h8-10,12H,1-7H2 |
| InChIKey | MDVGOOIANLZFCP-UHFFFAOYSA-N |
| SMILES | C12(CO)CC3CC(CC(C3)C1)C2 |
| CAS DataBase Reference | 770-71-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P280-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-36-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29061900 | |||||||||
| NFPA 704 |
|
1-Adamantanemethanol price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemicals (India) | H0420 | 1-Adamantanemethanol min. 99.0 % | 770-71-8 | 1G | ₹2400 | 2022-05-26 | Buy |
| TCI Chemicals (India) | H0420 | 1-Adamantanemethanol min. 99.0 % | 770-71-8 | 5G | ₹3500 | 2022-05-26 | Buy |
| ALFA India | ALF-B23831-14 | 1-Adamantanemethanol, 98% | 770-71-8 | 25g | ₹8642 | 2022-05-26 | Buy |
| TCI Chemicals (India) | H0420 | 1-Adamantanemethanol min. 99.0 % | 770-71-8 | 25G | ₹12200 | 2022-05-26 | Buy |
| ALFA India | ALF-B23831-06 | 1-Adamantanemethanol, 98% | 770-71-8 | 5g | ₹3590 | 2022-05-26 | Buy |
1-Adamantanemethanol Chemical Properties,Uses,Production
Description
1-Adamantanemethanol acts as guest molecule and forms β-cyclodextrin complexes. It reacts with 3,4,5,6-tetrafluorophthalonitrile to yield 3,4,5,6-tetra-(1-adamantylmethoxy)phthalonitrile.
Chemical Properties
white crystalline powder
Uses
1-Adamantanemethanol was used in the synthesis of axially disubstituted silicon(IV) phthalocyanines. It is used as a reagent in the synthesis of adamantane and noradamantane based histone deacetylase (HDAC) inhibitors for the treatment of cancer. It is also used as a reagent in the synthesis of (1-adamantyl)methyl glycidyl ether, a versatile building block for living polymerization.
References
Gopalan, B., et al.: Bioorg. Med. Chem. Lett., 23, 2532 (2013);
Suzuki, T., et al.: J. Med. Chem., 55, 9562 (2012);
Moers, C., et al.: Macromol. Rapid Comm., 35, 1075 (2014)
Purification Methods
Dissolve the adamantane in Et2O, wash it with aqueous 0.1N NaOH and H2O, dry over CaCl2, evaporate and recrystallise the residue from aqueous MeOH. [Stetter et al. Chem Ber 92 1629 1959, Beilstein 6 IV 400.]
1-Adamantanemethanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| CHEMSWORTH | +91-261-2397244 | New Delhi, India | 6707 | 30 | Inquiry |
| A.J Chemicals | 91-9810153283 | New Delhi, India | 6124 | 58 | Inquiry |
| TCI Chemicals (India) Pvt. Ltd. | 1800 425 7889 | New Delhi, India | 6778 | 58 | Inquiry |
| Alfa Aesar | 1 800 209 7001 | Maharashtra, India | 6913 | 58 | Inquiry |
| SynZeal Research Pvt Ltd | +1 226-802-2078 | Gujarat, India | 6522 | 58 | Inquiry |
| Pharmaffiliates Analytics and Synthetics P. Ltd | +91-172-5066494 | Haryana, India | 6773 | 58 | Inquiry |
| Reax Chemicals | 08048372701Ext 416 | Hyderabad, India | 4223 | 58 | Inquiry |
| Pharma Affiliates | 172-5066494 | Haryana, India | 6761 | 58 | Inquiry |
| Biopharmacule Speciality Chemicals P Ltd (India) | +91 40 6462 1866 | Hyderabad, India | 526 | 58 | Inquiry |
| Baba Fine Chemicals (BFC) | 91-9810180065 | Uttar Pradesh, India | 15 | 58 | Inquiry |