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3-Ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one

3-Ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one Structure
CAS No.
7416-34-4
Chemical Name:
3-Ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one
Synonyms
C07230;EN-1733A;MOLINDONE;EOS-60951;Molintone;Molindonum;indol-4(5h)-one;MOLINDONE USP/EP/BP;3-Ethyl-2-Methyl-5-(Morpholin-4-ylMethyl)-1,5,6,7-;3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)indol-4(5H)-one
CBNumber:
CB1497074
Molecular Formula:
C16H24N2O2
Molecular Weight:
276.37
MOL File:
7416-34-4.mol
MSDS File:
SDS
Modify Date:
2023/5/4 17:34:41

3-Ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one Properties

Melting point 180-181°
Boiling point 462.9±45.0 °C(Predicted)
Density 1.140±0.06 g/cm3(Predicted)
solubility H2O: 19 mg/mL
form solid
pka pKa 6.9(H2O,t =25,I=0.2) (Uncertain)
color off-white
CAS DataBase Reference 7416-34-4(CAS DataBase Reference)
NIST Chemistry Reference Indol-4(5h)-one, 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-(7416-34-4)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  NM3325000

3-Ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one Chemical Properties,Uses,Production

Uses

Antipsychotic.

Side effects

Molindone hydrochloride, a tetrahydro-indolone derivative, is a neuroleptic agent that is structurally unrelated to any of the other marketed neuroleptics. Molindone is less potent than haloperidol at blocking D2 receptors; however, it nonetheless can produce extrapyramidal side effects.

Metabolism

Metabolism studies in humans show molindone to be rapidly absorbed and metabolized when given orally. There are 36 recognized metabolites, with less than 2 to 3% unmetabolized molindone being excreted in urine and feces. Clinical studies show that the antipsychotic effects of molindone last more than 24 hours, suggesting that one or more metabolites may contribute to its activity in vivo (62).

3-Ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one Preparation Products And Raw materials

Global( 41)Suppliers
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CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
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Shanghai Richem International Co., Ltd 86-21-31263688 China 227 51 Inquiry
MOLINDONE 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4h-indol-4-on 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4h-indol-4-one 3-Ethyl-2-methyl-6-(4-morpholinylmethyl)-1,5,6,7-tetrahydro-4H-indol-4-one 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-indol-4(5h)-on 3-Ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)indol-4(5H)-one EN-1733A indol-4(5h)-one C07230 3-Ethyl-2-Methyl-5-(Morpholin-4-ylMethyl)-1,5,6,7- 4H-Indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-Methyl-5-(4-MorpholinylMethyl)- 3-ethyl-2-methyl-5-(morpholinomethyl)-1,5,6,7-tetrahydro-4H-indol-4-one 3-Ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one EOS-60951 MOLINDONE USP/EP/BP 3-Ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one USP/EP/BP Molindonum Molintone 7416-34-4